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146 related items for PubMed ID: 11181042

  • 1. FTY720, a novel immunosuppressive agent, induces apoptosis in human glioma cells.
    Sonoda Y, Yamamoto D, Sakurai S, Hasegawa M, Aizu-Yokota E, Momoi T, Kasahara T.
    Biochem Biophys Res Commun; 2001 Feb 23; 281(2):282-8. PubMed ID: 11181042
    [Abstract] [Full Text] [Related]

  • 2. Mutated focal adhesion kinase induces apoptosis in a human glioma cell line, T98G.
    Sakurai S, Sonoda Y, Koguchi E, Shinoura N, Hamada H, Kasahara T.
    Biochem Biophys Res Commun; 2002 Apr 26; 293(1):174-81. PubMed ID: 12054581
    [Abstract] [Full Text] [Related]

  • 3. Induction of apoptosis in human bladder cancer cells in vitro and in vivo caused by FTY720 treatment.
    Azuma H, Takahara S, Horie S, Muto S, Otsuki Y, Katsuoka Y.
    J Urol; 2003 Jun 26; 169(6):2372-7. PubMed ID: 12771800
    [Abstract] [Full Text] [Related]

  • 4. FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation.
    Lee TK, Man K, Ho JW, Sun CK, Ng KT, Wang XH, Wong YC, Ng IO, Xu R, Fan ST.
    Carcinogenesis; 2004 Dec 26; 25(12):2397-405. PubMed ID: 15297371
    [Abstract] [Full Text] [Related]

  • 5. Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway.
    Matsuda S, Minowa A, Suzuki S, Koyasu S.
    J Immunol; 1999 Mar 15; 162(6):3321-6. PubMed ID: 10092785
    [Abstract] [Full Text] [Related]

  • 6. A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells.
    Matsuoka Y, Nagahara Y, Ikekita M, Shinomiya T.
    Br J Pharmacol; 2003 Apr 15; 138(7):1303-12. PubMed ID: 12711631
    [Abstract] [Full Text] [Related]

  • 7. Anticarcinogenic effect of FTY720 in human prostate carcinoma DU145 cells: modulation of mitogenic signaling, FAK, cell-cycle entry and apoptosis.
    Permpongkosol S, Wang JD, Takahara S, Matsumiya K, Nonomura N, Nishimura K, Tsujimura A, Kongkanand A, Okuyama A.
    Int J Cancer; 2002 Mar 10; 98(2):167-72. PubMed ID: 11857403
    [Abstract] [Full Text] [Related]

  • 8. Butyrate-treated colonic Caco-2 cells exhibit defective integrin-mediated signaling together with increased apoptosis and differentiation.
    Lévy P, Robin H, Bertrand F, Kornprobst M, Capeau J.
    J Cell Physiol; 2003 Dec 10; 197(3):336-47. PubMed ID: 14566963
    [Abstract] [Full Text] [Related]

  • 9. FTY720 induces apoptosis in multiple myeloma cells and overcomes drug resistance.
    Yasui H, Hideshima T, Raje N, Roccaro AM, Shiraishi N, Kumar S, Hamasaki M, Ishitsuka K, Tai YT, Podar K, Catley L, Mitsiades CS, Richardson PG, Albert R, Brinkmann V, Chauhan D, Anderson KC.
    Cancer Res; 2005 Aug 15; 65(16):7478-84. PubMed ID: 16103102
    [Abstract] [Full Text] [Related]

  • 10. Distinct pathways of apoptosis triggered by FTY720, etoposide, and anti-Fas antibody in human T-lymphoma cell line (Jurkat cells).
    Fujino M, Li XK, Kitazawa Y, Guo L, Kawasaki M, Funeshima N, Amano T, Suzuki S.
    J Pharmacol Exp Ther; 2002 Mar 15; 300(3):939-45. PubMed ID: 11861801
    [Abstract] [Full Text] [Related]

  • 11. Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60.
    Sonoda Y, Matsumoto Y, Funakoshi M, Yamamoto D, Hanks SK, Kasahara T.
    J Biol Chem; 2000 May 26; 275(21):16309-15. PubMed ID: 10821872
    [Abstract] [Full Text] [Related]

  • 12. Antiapoptotic action of focal adhesion kinase (FAK) against ionizing radiation.
    Kasahara T, Koguchi E, Funakoshi M, Aizu-Yokota E, Sonoda Y.
    Antioxid Redox Signal; 2002 Jun 26; 4(3):491-9. PubMed ID: 12215217
    [Abstract] [Full Text] [Related]

  • 13. FTY720 induced Bcl-associated and Fas-independent apoptosis in human renal cancer cells in vitro and significantly reduced in vivo tumor growth in mouse xenograft.
    Ubai T, Azuma H, Kotake Y, Inamoto T, Takahara K, Ito Y, Kiyama S, Sakamoto T, Horie S, Muto S, Takahara S, Otsuki Y, Katsuoka Y.
    Anticancer Res; 2007 Jun 26; 27(1A):75-88. PubMed ID: 17352219
    [Abstract] [Full Text] [Related]

  • 14. T cell selective apoptosis by a novel immunosuppressant, FTY720, is closely regulated with Bcl-2.
    Nagahara Y, Ikekita M, Shinomiya T.
    Br J Pharmacol; 2002 Dec 26; 137(7):953-62. PubMed ID: 12429567
    [Abstract] [Full Text] [Related]

  • 15. Staurosporine induces endothelial cell apoptosis via focal adhesion kinase dephosphorylation and focal adhesion disassembly independent of focal adhesion kinase proteolysis.
    Kabir J, Lobo M, Zachary I.
    Biochem J; 2002 Oct 01; 367(Pt 1):145-55. PubMed ID: 12084011
    [Abstract] [Full Text] [Related]

  • 16. Simultaneous inhibition of focal adhesion kinase and SRC enhances detachment and apoptosis in colon cancer cell lines.
    Golubovskaya VM, Gross S, Kaur AS, Wilson RI, Xu LH, Yang XH, Cance WG.
    Mol Cancer Res; 2003 Aug 01; 1(10):755-64. PubMed ID: 12939401
    [Abstract] [Full Text] [Related]

  • 17. FTY720, a synthetic compound from Isaria sinclairii, inhibits proliferation and induces apoptosis in pancreatic cancer cells.
    Shen Y, Cai M, Xia W, Liu J, Zhang Q, Xie H, Wang C, Wang X, Zheng S.
    Cancer Lett; 2007 Sep 08; 254(2):288-97. PubMed ID: 17462818
    [Abstract] [Full Text] [Related]

  • 18. Down-regulation of procaspase-8 expression by focal adhesion kinase protects HL-60 cells from TRAIL-induced apoptosis.
    Tamagiku Y, Sonoda Y, Kunisawa M, Ichikawa D, Murakami Y, Aizu-Yokota E, Kasahara T.
    Biochem Biophys Res Commun; 2004 Oct 15; 323(2):445-52. PubMed ID: 15369772
    [Abstract] [Full Text] [Related]

  • 19. IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.
    Fujiwara H, Yamakuni T, Ueno M, Ishizuka M, Shinkawa T, Isobe T, Ohizumi Y.
    J Pharmacol Exp Ther; 2004 Sep 15; 310(3):1288-95. PubMed ID: 15161934
    [Abstract] [Full Text] [Related]

  • 20. Immunomodulator FTY720 Induces eNOS-dependent arterial vasodilatation via the lysophospholipid receptor S1P3.
    Tölle M, Levkau B, Keul P, Brinkmann V, Giebing G, Schönfelder G, Schäfers M, von Wnuck Lipinski K, Jankowski J, Jankowski V, Chun J, Zidek W, Van der Giet M.
    Circ Res; 2005 Apr 29; 96(8):913-20. PubMed ID: 15802614
    [Abstract] [Full Text] [Related]

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