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Journal Abstract Search

414 related items for PubMed ID: 11196150

  • 1. Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro.
    End DW, Smets G, Todd AV, Applegate TL, Fuery CJ, Angibaud P, Venet M, Sanz G, Poignet H, Skrzat S, Devine A, Wouters W, Bowden C.
    Cancer Res; 2001 Jan 01; 61(1):131-7. PubMed ID: 11196150
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  • 2. Preclinical antitumor activity and pharmacodynamic studies with the farnesyl protein transferase inhibitor R115777 in human breast cancer.
    Kelland LR, Smith V, Valenti M, Patterson L, Clarke PA, Detre S, End D, Howes AJ, Dowsett M, Workman P, Johnston SR.
    Clin Cancer Res; 2001 Nov 01; 7(11):3544-50. PubMed ID: 11705875
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  • 3. Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
    Lobell RB, Omer CA, Abrams MT, Bhimnathwala HG, Brucker MJ, Buser CA, Davide JP, deSolms SJ, Dinsmore CJ, Ellis-Hutchings MS, Kral AM, Liu D, Lumma WC, Machotka SV, Rands E, Williams TM, Graham SL, Hartman GD, Oliff AI, Heimbrook DC, Kohl NE.
    Cancer Res; 2001 Dec 15; 61(24):8758-68. PubMed ID: 11751396
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  • 4. Farnesyl protein transferase inhibitor ZARNESTRA R115777 - history of a discovery.
    Venet M, End D, Angibaud P.
    Curr Top Med Chem; 2003 Dec 15; 3(10):1095-102. PubMed ID: 12769710
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  • 5. Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice.
    Liu M, Bryant MS, Chen J, Lee S, Yaremko B, Li Z, Dell J, Lipari P, Malkowski M, Prioli N, Rossman RR, Korfmacher WA, Nomeir AA, Lin CC, Mallams AK, Doll RJ, Catino JJ, Girijavallabhan VM, Kirschmeier P, Bishop WR.
    Cancer Chemother Pharmacol; 1999 Dec 15; 43(1):50-8. PubMed ID: 9923541
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  • 6. Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells.
    Le Gouill S, Pellat-Deceunynck C, Harousseau JL, Rapp MJ, Robillard N, Bataille R, Amiot M.
    Leukemia; 2002 Sep 15; 16(9):1664-7. PubMed ID: 12200678
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  • 12. The farnesyltransferase inhibitor R115777 reduces hypoxia and matrix metalloproteinase 2 expression in human glioma xenograft.
    Delmas C, End D, Rochaix P, Favre G, Toulas C, Cohen-Jonathan E.
    Clin Cancer Res; 2003 Dec 01; 9(16 Pt 1):6062-8. PubMed ID: 14676133
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  • 13. Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines.
    Lerner EC, Zhang TT, Knowles DB, Qian Y, Hamilton AD, Sebti SM.
    Oncogene; 1997 Sep 01; 15(11):1283-8. PubMed ID: 9315095
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  • 17. Antitumor activity of ER-51785, a new peptidomimetic inhibitor of farnesyl transferase: synergistic effect in combination with paclitaxel.
    Nakamura K, Yamaguchi A, Namiki M, Ishihara H, Nagasu T, Kowalczyk JJ, Garcia AM, Lewis MD, Yoshimatsu K.
    Oncol Res; 2001 Sep 01; 12(11-12):477-84. PubMed ID: 11939411
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  • 19. The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways.
    Caraglia M, Marra M, Viscomi C, D'Alessandro AM, Budillon A, Meo G, Arra C, Barbieri A, Rapp UR, Baldi A, Tassone P, Venuta S, Abbruzzese A, Tagliaferri P.
    Int J Cancer; 2007 Nov 15; 121(10):2317-30. PubMed ID: 17657738
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  • 20. Inhibition of human tumor xenograft growth by treatment with the farnesyl transferase inhibitor B956.
    Nagasu T, Yoshimatsu K, Rowell C, Lewis MD, Garcia AM.
    Cancer Res; 1995 Nov 15; 55(22):5310-4. PubMed ID: 7585593
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