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112 related items for PubMed ID: 11196448

  • 1. Molecular modeling of the hamster adrenal P450C17.
    Mathieu AP, Auchus RJ, LeHoux JG.
    Endocr Res; 2000 Nov; 26(4):723-8. PubMed ID: 11196448
    [Abstract] [Full Text] [Related]

  • 2. Characterization of the adrenal cytochrome P450C17 in the hamster, a small animal model for the study of adrenal dehydroepiandrosterone biosynthesis.
    Cloutier M, Fleury A, Courtemanche J, Ducharme L, Mason JI, Lehoux JG.
    DNA Cell Biol; 1997 Mar; 16(3):357-68. PubMed ID: 9115645
    [Abstract] [Full Text] [Related]

  • 3. Comparison of the hamster and human adrenal P450c17 (17 alpha-hydroxylase/17,20-lyase) using site-directed mutagenesis and molecular modeling.
    Mathieu AP, Auchus RJ, LeHoux JG.
    J Steroid Biochem Mol Biol; 2002 Jan; 80(1):99-107. PubMed ID: 11867269
    [Abstract] [Full Text] [Related]

  • 4. Comparison of the 17 alpha-hydroxylase/C17,20-lyase activities of porcine, guinea pig and bovine P450c17 using purified recombinant fusion proteins containing P450c17 linked to NADPH-P450 reductase.
    Shet MS, Fisher CW, Tremblay Y, Belanger A, Conley AJ, Mason JI, Estabrook RW.
    Drug Metab Rev; 2007 Jan; 39(2-3):289-307. PubMed ID: 17786622
    [Abstract] [Full Text] [Related]

  • 5. The molecular basis of isolated 17,20 lyase deficiency.
    Miller WL, Geller DH, Auchus RJ.
    Endocr Res; 1998 Jan; 24(3-4):817-25. PubMed ID: 9888582
    [Abstract] [Full Text] [Related]

  • 6. Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase.
    Swart P, Swart AC, Waterman MR, Estabrook RW, Mason JI.
    J Clin Endocrinol Metab; 1993 Jul; 77(1):98-102. PubMed ID: 8325965
    [Abstract] [Full Text] [Related]

  • 7. Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: contributions of serine106 and P450 reductase.
    Lin D, Black SM, Nagahama Y, Miller WL.
    Endocrinology; 1993 Jun; 132(6):2498-506. PubMed ID: 8504753
    [Abstract] [Full Text] [Related]

  • 8. Molecular modeling of human P450c17 (17alpha-hydroxylase/17,20-lyase): insights into reaction mechanisms and effects of mutations.
    Auchus RJ, Miller WL.
    Mol Endocrinol; 1999 Jul; 13(7):1169-82. PubMed ID: 10406467
    [Abstract] [Full Text] [Related]

  • 9. Studies of the human fetal adrenal gland--properties of 17alpha-hydroxylase and C17-C20 lyase in the biosynthesis of dehydroepiandrosterone from pregnenolone.
    Shibusawa H, Sano Y, Yoshida N, Okinaga S, Arai K.
    J Steroid Biochem; 1978 Nov; 9(11):1125-32. PubMed ID: 34065
    [No Abstract] [Full Text] [Related]

  • 10. Molecular dynamics of substrate complexes with hamster cytochrome P450c17 (CYP17): mechanistic approach to understanding substrate binding and activities.
    Mathieu AP, LeHoux JG, Auchus RJ.
    Biochim Biophys Acta; 2003 Feb 17; 1619(3):291-300. PubMed ID: 12573489
    [Abstract] [Full Text] [Related]

  • 11. Modulation of 17alpha-hydroxylase/17,20-lyase activity of guinea pig cytochrome P450c17 by site-directed mutagenesis.
    Beaudoin C, Lavallée B, Tremblay Y, Hum DW, Breton R, de Launoit Y, Bélanger A.
    DNA Cell Biol; 1998 Aug 17; 17(8):707-15. PubMed ID: 9726253
    [Abstract] [Full Text] [Related]

  • 12. Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species.
    Arlt W, Martens JW, Song M, Wang JT, Auchus RJ, Miller WL.
    Endocrinology; 2002 Dec 17; 143(12):4665-72. PubMed ID: 12446594
    [Abstract] [Full Text] [Related]

  • 13. Modeling and mutagenesis of the active site of human P450c17.
    Lin D, Zhang LH, Chiao E, Miller WL.
    Mol Endocrinol; 1994 Mar 17; 8(3):392-402. PubMed ID: 8015556
    [Abstract] [Full Text] [Related]

  • 14. Pitfalls in characterizing P450c17 mutations associated with isolated 17,20-lyase deficiency.
    Gupta MK, Geller DH, Auchus RJ.
    J Clin Endocrinol Metab; 2001 Sep 17; 86(9):4416-23. PubMed ID: 11549685
    [Abstract] [Full Text] [Related]

  • 15. Immunohistochemical localization and biological activity of the steroidogenic enzyme cytochrome P450 17alpha-hydroxylase/C17, 20-lyase (P450C17) in the frog brain and pituitary.
    Do Rego JL, Tremblay Y, Luu-The V, Repetto E, Castel H, Vallarino M, Bélanger A, Pelletier G, Vaudry H.
    J Neurochem; 2007 Jan 17; 100(1):251-68. PubMed ID: 17076760
    [Abstract] [Full Text] [Related]

  • 16. Quantitative changes in ovarian 17 alpha-hydroxylase/C17,20-lyase and aromatase activities during the estrous cycle of the hamster.
    Johnson DC.
    Proc Soc Exp Biol Med; 1987 Jan 17; 184(1):14-8. PubMed ID: 3491994
    [Abstract] [Full Text] [Related]

  • 17. Conversion of pregnenolone to DHEA by human 17alpha-hydroxylase/17, 20-lyase (P450c17). Evidence that DHEA is produced from the released intermediate, 17alpha-hydroxypregnenolone.
    Soucy P, Luu-The V.
    Eur J Biochem; 2000 Jun 17; 267(11):3243-7. PubMed ID: 10824109
    [Abstract] [Full Text] [Related]

  • 18. Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues.
    Chung BC, Picado-Leonard J, Haniu M, Bienkowski M, Hall PF, Shively JE, Miller WL.
    Proc Natl Acad Sci U S A; 1987 Jan 17; 84(2):407-11. PubMed ID: 3025870
    [Abstract] [Full Text] [Related]

  • 19. Biochemical differences between rat and human cytochrome P450c17 support the different steroidogenic needs of these two species.
    Brock BJ, Waterman MR.
    Biochemistry; 1999 Feb 02; 38(5):1598-606. PubMed ID: 9931027
    [Abstract] [Full Text] [Related]

  • 20. Ontogeny of the adrenal gland in the spiny mouse, with particular reference to production of the steroids cortisol and dehydroepiandrosterone.
    Quinn TA, Ratnayake U, Dickinson H, Nguyen TH, McIntosh M, Castillo-Melendez M, Conley AJ, Walker DW.
    Endocrinology; 2013 Mar 02; 154(3):1190-201. PubMed ID: 23354096
    [Abstract] [Full Text] [Related]


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