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424 related items for PubMed ID: 11198926

  • 1. Oligonucleotide sequence-specific inhibition of gene expression, tumor growth inhibition, and modulation of cAMP signaling by an RNA-DNA hybrid antisense targeted to protein kinase A RIalpha subunit.
    Nesterova M, Cho-Chung YS.
    Antisense Nucleic Acid Drug Dev; 2000 Dec; 10(6):423-33. PubMed ID: 11198926
    [Abstract] [Full Text] [Related]

  • 2. Compensatory stabilization of RIIbeta protein, cell cycle deregulation, and growth arrest in colon and prostate carcinoma cells by antisense-directed down-regulation of protein kinase A RIalpha protein.
    Nesterova M, Noguchi K, Park YG, Lee YN, Cho-Chung YS.
    Clin Cancer Res; 2000 Sep; 6(9):3434-41. PubMed ID: 10999726
    [Abstract] [Full Text] [Related]

  • 3. Antisense protein kinase A RIalpha inhibits 7,12-dimethylbenz(a)anthracene-induction of mammary cancer: blockade at the initial phase of carcinogenesis.
    Nesterova MV, Cho-Chung YS.
    Clin Cancer Res; 2004 Jul 01; 10(13):4568-77. PubMed ID: 15240549
    [Abstract] [Full Text] [Related]

  • 4. Chemoprevention with protein kinase A RIalpha antisense in DMBA-mammary carcinogenesis.
    Nesterova MV, Cho-Chung YS.
    Ann N Y Acad Sci; 2005 Nov 01; 1058():255-64. PubMed ID: 16394142
    [Abstract] [Full Text] [Related]

  • 5. Antisense protein kinase A RIalpha acts synergistically with hydroxycamptothecin to inhibit growth and induce apoptosis in human cancer cells: molecular basis for combinatorial therapy.
    Cho YS, Cho-Chung YS.
    Clin Cancer Res; 2003 Mar 01; 9(3):1171-8. PubMed ID: 12631623
    [Abstract] [Full Text] [Related]

  • 6. Protein kinase A RIalpha antisense inhibition of PC3M prostate cancer cell growth: Bcl-2 hyperphosphorylation, Bax up-regulation, and Bad-hypophosphorylation.
    Cho YS, Kim MK, Tan L, Srivastava R, Agrawal S, Cho-Chung YS.
    Clin Cancer Res; 2002 Feb 01; 8(2):607-14. PubMed ID: 11839683
    [Abstract] [Full Text] [Related]

  • 7. Nuclear translocation of the catalytic subunit of protein kinase A induced by an antisense oligonucleotide directed against the RIalpha regulatory subunit.
    Neary CL, Cho-Chung YS.
    Oncogene; 2001 Nov 29; 20(55):8019-24. PubMed ID: 11753685
    [Abstract] [Full Text] [Related]

  • 8. CpG immunomer DNA enhances antisense protein kinase A RIalpha inhibition of multidrug-resistant colon carcinoma growth in nude mice: molecular basis for combinatorial therapy.
    Nesterova MV, Johnson NR, Stewart T, Abrams S, Cho-Chung YS.
    Clin Cancer Res; 2005 Aug 15; 11(16):5950-5. PubMed ID: 16115938
    [Abstract] [Full Text] [Related]

  • 9. Combined blockade of protein kinase A and bcl-2 by antisense strategy induces apoptosis and inhibits tumor growth and angiogenesis.
    Tortora G, Caputo R, Damiano V, Bianco R, Fontanini G, Cuccato S, De Placido S, Bianco AR, Ciardiello F.
    Clin Cancer Res; 2001 Aug 15; 7(8):2537-44. PubMed ID: 11489837
    [Abstract] [Full Text] [Related]

  • 10. Experimental gene therapy of human colon cancer.
    Bold RJ, Warren RE, Ishizuka J, Cho-Chung YS, Townsend CM, Thompson JC.
    Surgery; 1994 Aug 15; 116(2):189-95; discussion 195-6. PubMed ID: 8047985
    [Abstract] [Full Text] [Related]

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  • 13. Antitumor activity and pharmacokinetics of a mixed-backbone antisense oligonucleotide targeted to the RIalpha subunit of protein kinase A after oral administration.
    Wang H, Cai Q, Zeng X, Yu D, Agrawal S, Zhang R.
    Proc Natl Acad Sci U S A; 1999 Nov 23; 96(24):13989-94. PubMed ID: 10570186
    [Abstract] [Full Text] [Related]

  • 14. Isozymes of cyclic AMP-dependent protein kinases (PKA) in human lymphoid cell lines: levels of endogenous cAMP influence levels of PKA subunits and growth in lymphoid cell lines.
    Skålhegg BS, Johansen AK, Levy FO, Andersson KB, Aandahl EM, Blomhoff HK, Hansson V, Taskén K.
    J Cell Physiol; 1998 Oct 23; 177(1):85-93. PubMed ID: 9731748
    [Abstract] [Full Text] [Related]

  • 15. Patterns of cyclic AMP-dependent protein kinase gene expression during ontogeny of the murine palate.
    Greene RM, Lloyd MR, Uberti M, Nugent P, Pisano MM.
    J Cell Physiol; 1995 Jun 23; 163(3):431-40. PubMed ID: 7775586
    [Abstract] [Full Text] [Related]

  • 16. Activated protein kinase A is required for differentiation-dependent transcription of the decidual prolactin gene in human endometrial stromal cells.
    Telgmann R, Maronde E, Taskén K, Gellersen B.
    Endocrinology; 1997 Mar 23; 138(3):929-37. PubMed ID: 9048592
    [Abstract] [Full Text] [Related]

  • 17. An antisense oligodeoxynucleotide that depletes RI alpha subunit of cyclic AMP-dependent protein kinase induces growth inhibition in human cancer cells.
    Yokozaki H, Budillon A, Tortora G, Meissner S, Beaucage SL, Miki K, Cho-Chung YS.
    Cancer Res; 1993 Feb 15; 53(4):868-72. PubMed ID: 8428367
    [Abstract] [Full Text] [Related]

  • 18. Antisense DNA-targeting protein kinase A-RIA subunit: a novel approach to cancer treatment.
    Cho-Chung YS, Nesterova M, Pepe S, Lee GR, Noguchi K, Srivastava RK, Srivastava AR, Alper O, Park YG, Lee YN.
    Front Biosci; 1999 Dec 01; 4():D898-907. PubMed ID: 10577386
    [Abstract] [Full Text] [Related]

  • 19. Type II protein kinase A up-regulation is sufficient to induce growth inhibition in SK-N-SH human neuroblastoma cells.
    Kim SN, Lee GR, Hwang ES, Lee JH, Park SD, Cho-Chung YS, Hong SH.
    Biochem Biophys Res Commun; 1997 Mar 17; 232(2):469-73. PubMed ID: 9125203
    [Abstract] [Full Text] [Related]

  • 20. Ala99ser mutation in RI alpha regulatory subunit of protein kinase A causes reduced kinase activation by cAMP and arrest of hormone-dependent breast cancer cell growth.
    Lee GR, Kim SN, Noguchi K, Park SD, Hong SH, Cho-Chung YS.
    Mol Cell Biochem; 1999 May 17; 195(1-2):77-86. PubMed ID: 10395071
    [Abstract] [Full Text] [Related]


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