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Journal Abstract Search

133 related items for PubMed ID: 11206458

  • 1. Diastereoselective synthesis, activity and chiral stability of cyclic alkoxyketone inhibitors of cathepsin K.
    Fenwick AE, Gribble AD, Ife RJ, Stevens N, Witherington J.
    Bioorg Med Chem Lett; 2001 Jan 22; 11(2):199-202. PubMed ID: 11206458
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  • 2. Solid-phase synthesis of cyclic alkoxyketones, inhibitors of the cysteine protease cathepsin K.
    Fenwick AE, Garnier B, Gribble AD, Ife RJ, Rawlings AD, Witherington J.
    Bioorg Med Chem Lett; 2001 Jan 22; 11(2):195-8. PubMed ID: 11206457
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  • 5. Benzodioxocin-3-ones and N-acyl-3-amino-3-buten-2-ones: novel classes of cathepsin K cysteine protease inhibitors.
    Yamashita DS, Xie R, Lin H, Wang B, Shi SD, Quinn CJ, Hemling ME, Hissong C, Tomaszek TA, Veber DF.
    J Pept Res; 2004 Mar 22; 63(3):265-9. PubMed ID: 15049838
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  • 7. Novel, potent P2-P3 pyrrolidine derivatives of ketoamide-based cathepsin K inhibitors.
    Barrett DG, Catalano JG, Deaton DN, Hassell AM, Long ST, Miller AB, Miller LR, Ray JA, Samano V, Shewchuk LM, Wells-Knecht KJ, Willard DH, Wright LL.
    Bioorg Med Chem Lett; 2006 Mar 15; 16(6):1735-9. PubMed ID: 16376075
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  • 8. Discovery and parallel synthesis of a new class of cathepsin K inhibitors.
    Smith RA, Bhargava A, Browe C, Chen J, Dumas J, Hatoum-Mokdad H, Romero R.
    Bioorg Med Chem Lett; 2001 Nov 19; 11(22):2951-4. PubMed ID: 11677133
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  • 9. Solid-phase synthesis of a combinatorial array of 1,3-bis(acylamino)-2-butanones, inhibitors of the cysteine proteases cathepsins K and L.
    Yamashita DS, Dong X, Oh HJ, Brook CS, Tomaszek TA, Szewczuk L, Tew DG, Veber DF.
    J Comb Chem; 1999 Nov 19; 1(3):207-15. PubMed ID: 10746010
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  • 10. P2-P3 conformationally constrained ketoamide-based inhibitors of cathepsin K.
    Barrett DG, Boncek VM, Catalano JG, Deaton DN, Hassell AM, Jurgensen CH, Long ST, McFadyen RB, Miller AB, Miller LR, Payne JA, Ray JA, Samano V, Shewchuk LM, Tavares FX, Wells-Knecht KJ, Willard DH, Wright LL, Zhou HQ.
    Bioorg Med Chem Lett; 2005 Aug 01; 15(15):3540-6. PubMed ID: 15982880
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  • 11. Arylamine based cathepsin K inhibitors: investigating P3 heterocyclic substituents.
    Shinozuka T, Shimada K, Matsui S, Yamane T, Ama M, Fukuda T, Taki M, Takeda Y, Otsuka E, Yamato M, Naito S.
    Bioorg Med Chem; 2006 Oct 15; 14(20):6807-19. PubMed ID: 16829073
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  • 13. Design and synthesis of diaminopyrrolidinone inhibitors of human osteoclast cathepsin K.
    Duffy KJ, Ridgers LH, DesJarlais RL, Tomaszek TA, Bossard MJ, Thompson SK, Keenan RM, Veber DF.
    Bioorg Med Chem Lett; 1999 Jul 19; 9(14):1907-10. PubMed ID: 10450951
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  • 14. 3,4-disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P3 elements for potency and selectivity.
    Setti EL, Davis D, Janc JW, Jeffery DA, Cheung H, Yu W.
    Bioorg Med Chem Lett; 2005 Mar 01; 15(5):1529-34. PubMed ID: 15713422
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  • 16. 4-Aminophenoxyacetic acids as a novel class of reversible cathepsin K inhibitors.
    Shinozuka T, Shimada K, Matsui S, Yamane T, Ama M, Fukuda T, Taki M, Naito S.
    Bioorg Med Chem Lett; 2006 Mar 15; 16(6):1502-5. PubMed ID: 16380250
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  • 17. Cyclic ketone inhibitors of the cysteine protease cathepsin K.
    Marquis RW, Ru Y, Zeng J, Trout RE, LoCastro SM, Gribble AD, Witherington J, Fenwick AE, Garnier B, Tomaszek T, Tew D, Hemling ME, Quinn CJ, Smith WW, Zhao B, McQueney MS, Janson CA, D'Alessio K, Veber DF.
    J Med Chem; 2001 Mar 01; 44(5):725-36. PubMed ID: 11262083
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  • 18. Potent dipeptidylketone inhibitors of the cysteine protease cathepsin K.
    Marquis RW, Ru Y, Yamashita DS, Oh HJ, Yen J, Thompson SK, Carr TJ, Levy MA, Tomaszek TA, Ijames CF, Smith WW, Zhao B, Janson CA, Abdel-Meguid SS, D'Alessio KJ, McQueney MS, Veber DF.
    Bioorg Med Chem; 1999 Apr 01; 7(4):581-8. PubMed ID: 10353637
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  • 19. Novel and potent cyclic cyanamide-based cathepsin K inhibitors.
    Deaton DN, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Tavares FX, Willard DH, Wright LL.
    Bioorg Med Chem Lett; 2005 Apr 01; 15(7):1815-9. PubMed ID: 15780613
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  • 20. Arylaminoethyl amides as inhibitors of the cysteine protease cathepsin K-investigating P1' substituents.
    Altmann E, Green J, Tintelnot-Blomley M.
    Bioorg Med Chem Lett; 2003 Jun 16; 13(12):1997-2001. PubMed ID: 12781182
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