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863 related items for PubMed ID: 11221844

  • 1. Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): caspase-8 is required for TRAIL-induced apoptosis.
    Seol DW, Li J, Seol MH, Park SY, Talanian RV, Billiar TR.
    Cancer Res; 2001 Feb 01; 61(3):1138-43. PubMed ID: 11221844
    [Abstract] [Full Text] [Related]

  • 2. The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.
    Ozoren N, Kim K, Burns TF, Dicker DT, Moscioni AD, El-Deiry WS.
    Cancer Res; 2000 Nov 15; 60(22):6259-65. PubMed ID: 11103780
    [Abstract] [Full Text] [Related]

  • 3. Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways.
    Suliman A, Lam A, Datta R, Srivastava RK.
    Oncogene; 2001 Apr 19; 20(17):2122-33. PubMed ID: 11360196
    [Abstract] [Full Text] [Related]

  • 4. The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway.
    Liu B, Fan Z.
    Oncogene; 2001 Jun 21; 20(28):3726-34. PubMed ID: 11439335
    [Abstract] [Full Text] [Related]

  • 5. Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand.
    Mitsiades N, Poulaki V, Tseleni-Balafouta S, Koutras DA, Stamenkovic I.
    Cancer Res; 2000 Aug 01; 60(15):4122-9. PubMed ID: 10945619
    [Abstract] [Full Text] [Related]

  • 6. Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells.
    Izeradjene K, Douglas L, Delaney A, Houghton JA.
    Clin Cancer Res; 2004 Oct 01; 10(19):6650-60. PubMed ID: 15475455
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  • 9. Casein kinase I attenuates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by regulating the recruitment of fas-associated death domain and procaspase-8 to the death-inducing signaling complex.
    Izeradjene K, Douglas L, Delaney AB, Houghton JA.
    Cancer Res; 2004 Nov 01; 64(21):8036-44. PubMed ID: 15520213
    [Abstract] [Full Text] [Related]

  • 10. FADD deficiency sensitises Jurkat T cells to TNF-alpha-dependent necrosis during activation-induced cell death.
    Lawrence CP, Chow SC.
    FEBS Lett; 2005 Nov 21; 579(28):6465-72. PubMed ID: 16289096
    [Abstract] [Full Text] [Related]

  • 11. Reconstitution of caspase-8 sensitizes JB6 cells to TRAIL.
    Kim IK, Chung CW, Woo HN, Hong GS, Nagata S, Jung YK.
    Biochem Biophys Res Commun; 2000 Oct 22; 277(2):311-6. PubMed ID: 11032723
    [Abstract] [Full Text] [Related]

  • 12. Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2- or Bcl-xL-overexpressing chemotherapy-resistant tumor cells.
    Walczak H, Bouchon A, Stahl H, Krammer PH.
    Cancer Res; 2000 Jun 01; 60(11):3051-7. PubMed ID: 10850456
    [Abstract] [Full Text] [Related]

  • 13. Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionizing radiation in leukemic cells.
    Gong B, Almasan A.
    Cancer Res; 2000 Oct 15; 60(20):5754-60. PubMed ID: 11059770
    [Abstract] [Full Text] [Related]

  • 14. Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis.
    Kim JY, Kim YH, Chang I, Kim S, Pak YK, Oh BH, Yagita H, Jung YK, Oh YJ, Lee MS.
    Oncogene; 2002 May 09; 21(20):3139-48. PubMed ID: 12082629
    [Abstract] [Full Text] [Related]

  • 15. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria.
    Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P.
    Cancer Res; 2001 Oct 01; 61(19):7339-48. PubMed ID: 11585775
    [Abstract] [Full Text] [Related]

  • 16. Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling.
    Chen X, Kandasamy K, Srivastava RK.
    Cancer Res; 2003 Mar 01; 63(5):1059-66. PubMed ID: 12615723
    [Abstract] [Full Text] [Related]

  • 17. E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation.
    Shao R, Lee DF, Wen Y, Ding Y, Xia W, Ping B, Yagita H, Spohn B, Hung MC.
    Mol Cancer Res; 2005 Apr 01; 3(4):219-26. PubMed ID: 15831675
    [Abstract] [Full Text] [Related]

  • 18. IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC.
    Ramaswamy M, Efimova EV, Martinez O, Mulherkar NU, Singh SP, Prabhakar BS.
    Oncogene; 2004 Aug 12; 23(36):6083-94. PubMed ID: 15208670
    [Abstract] [Full Text] [Related]

  • 19. Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
    Ozören N, El-Deiry WS.
    Neoplasia; 2002 Aug 12; 4(6):551-7. PubMed ID: 12407450
    [Abstract] [Full Text] [Related]

  • 20. Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis factor-related apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential.
    Hotta T, Suzuki H, Nagai S, Yamamoto K, Imakiire A, Takada E, Itoh M, Mizuguchi J.
    J Orthop Res; 2003 Sep 12; 21(5):949-57. PubMed ID: 12919886
    [Abstract] [Full Text] [Related]


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