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179 related items for PubMed ID: 11222388

  • 1. The antiangiogenic protein kinase inhibitors SU5416 and SU6668 inhibit the SCF receptor (c-kit) in a human myeloid leukemia cell line and in acute myeloid leukemia blasts.
    Smolich BD, Yuen HA, West KA, Giles FJ, Albitar M, Cherrington JM.
    Blood; 2001 Mar 01; 97(5):1413-21. PubMed ID: 11222388
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  • 2. The protein tyrosine kinase inhibitor SU5614 inhibits VEGF-induced endothelial cell sprouting and induces growth arrest and apoptosis by inhibition of c-kit in AML cells.
    Spiekermann K, Faber F, Voswinckel R, Hiddemann W.
    Exp Hematol; 2002 Jul 01; 30(7):767-73. PubMed ID: 12135675
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  • 3. Effects of SU5416, a small molecule tyrosine kinase receptor inhibitor, on FLT3 expression and phosphorylation in patients with refractory acute myeloid leukemia.
    O'Farrell AM, Yuen HA, Smolich B, Hannah AL, Louie SG, Hong W, Stopeck AT, Silverman LR, Lancet JE, Karp JE, Albitar M, Cherrington JM, Giles FJ.
    Leuk Res; 2004 Jul 01; 28(7):679-89. PubMed ID: 15158089
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  • 6. Downregulation of VEGF-A, STAT5 and AKT in acute myeloid leukemia blasts of patients treated with SU5416.
    Loges S, Tinnefeld H, Metzner A, Jücker M, Butzal M, Bruweleit M, Fischer U, Draab E, Schuch G, O'-Farrel AM, Hossfeld DK, Bokemeyer C, Fiedler W.
    Leuk Lymphoma; 2006 Dec 01; 47(12):2601-9. PubMed ID: 17169805
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  • 12. Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells.
    Faderl S, Pal A, Bornmann W, Albitar M, Maxwell D, Van Q, Peng Z, Harris D, Liu Z, Hazan-Halevy I, Kantarjian HM, Estrov Z.
    Cancer Res; 2009 May 01; 69(9):3910-7. PubMed ID: 19383925
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  • 14. Inhibition of vascular endothelial growth factor-associated tyrosine kinase activity with SU5416 blocks sprouting in the microvascular endothelial cell spheroid model of angiogenesis.
    Haspel HC, Scicli GM, McMahon G, Scicli AG.
    Microvasc Res; 2002 May 01; 63(3):304-15. PubMed ID: 11969307
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  • 15. The angiogenesis inhibitor SU5416 has long-lasting effects on vascular endothelial growth factor receptor phosphorylation and function.
    Mendel DB, Schreck RE, West DC, Li G, Strawn LM, Tanciongco SS, Vasile S, Shawver LK, Cherrington JM.
    Clin Cancer Res; 2000 Dec 01; 6(12):4848-58. PubMed ID: 11156244
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  • 16. Antiangiogenic effect by SU5416 is partly attributable to inhibition of Flt-1 receptor signaling.
    Itokawa T, Nokihara H, Nishioka Y, Sone S, Iwamoto Y, Yamada Y, Cherrington J, McMahon G, Shibuya M, Kuwano M, Ono M.
    Mol Cancer Ther; 2002 Mar 01; 1(5):295-302. PubMed ID: 12489845
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  • 18. SU6668 inhibits Flk-1/KDR and PDGFRbeta in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice.
    Laird AD, Christensen JG, Li G, Carver J, Smith K, Xin X, Moss KG, Louie SG, Mendel DB, Cherrington JM.
    FASEB J; 2002 May 01; 16(7):681-90. PubMed ID: 11978732
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