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423 related items for PubMed ID: 11229480

  • 1. Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptors.
    Ihn H, Yamane K, Kubo M, Tamaki K.
    Arthritis Rheum; 2001 Feb; 44(2):474-80. PubMed ID: 11229480
    [Abstract] [Full Text] [Related]

  • 2. An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma.
    Pannu J, Gore-Hyer E, Yamanaka M, Smith EA, Rubinchik S, Dong JY, Jablonska S, Blaszczyk M, Trojanowska M.
    Arthritis Rheum; 2004 May; 50(5):1566-77. PubMed ID: 15146427
    [Abstract] [Full Text] [Related]

  • 3. Involvement of alphavbeta5 integrin-mediated activation of latent transforming growth factor beta1 in autocrine transforming growth factor beta signaling in systemic sclerosis fibroblasts.
    Asano Y, Ihn H, Yamane K, Jinnin M, Mimura Y, Tamaki K.
    Arthritis Rheum; 2005 Sep; 52(9):2897-905. PubMed ID: 16142753
    [Abstract] [Full Text] [Related]

  • 4. Differential effects of the immunosuppressant FK-506 on human alpha2(I) collagen gene expression and transforming growth factor beta signaling in normal and scleroderma fibroblasts.
    Asano Y, Ihn H, Yamane K, Jinnin M, Mimura Y, Tamaki K.
    Arthritis Rheum; 2005 Apr; 52(4):1237-47. PubMed ID: 15818662
    [Abstract] [Full Text] [Related]

  • 5. Increased phosphorylation of transcription factor Sp1 in scleroderma fibroblasts: association with increased expression of the type I collagen gene.
    Ihn H, Tamaki K.
    Arthritis Rheum; 2000 Oct; 43(10):2240-7. PubMed ID: 11037883
    [Abstract] [Full Text] [Related]

  • 6. Basic fibroblast growth factor inhibits basal and transforming growth factor-beta induced collagen alpha 2(I) gene expression in scleroderma and normal fibroblasts.
    Ichiki Y, Smith EA, LeRoy EC, Trojanowska M.
    J Rheumatol; 1997 Jan; 24(1):90-5. PubMed ID: 9002017
    [Abstract] [Full Text] [Related]

  • 7. Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.
    Pannu J, Gardner H, Shearstone JR, Smith E, Trojanowska M.
    Arthritis Rheum; 2006 Sep; 54(9):3011-21. PubMed ID: 16947635
    [Abstract] [Full Text] [Related]

  • 8. Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor beta responses in skin fibroblasts.
    Mori Y, Ishida W, Bhattacharyya S, Li Y, Platanias LC, Varga J.
    Arthritis Rheum; 2004 Dec; 50(12):4008-21. PubMed ID: 15593186
    [Abstract] [Full Text] [Related]

  • 9. Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts.
    Mori Y, Chen SJ, Varga J.
    Arthritis Rheum; 2003 Jul; 48(7):1964-78. PubMed ID: 12847691
    [Abstract] [Full Text] [Related]

  • 10. Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts.
    Ihn H, Yamane K, Asano Y, Jinnin M, Tamaki K.
    Rheumatology (Oxford); 2006 Feb; 45(2):157-65. PubMed ID: 16319104
    [Abstract] [Full Text] [Related]

  • 11. Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta.
    Bhattacharyya S, Ghosh AK, Pannu J, Mori Y, Takagawa S, Chen G, Trojanowska M, Gilliam AC, Varga J.
    Arthritis Rheum; 2005 Apr; 52(4):1248-58. PubMed ID: 15818659
    [Abstract] [Full Text] [Related]

  • 12. Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors.
    Kawaguchi Y, Takagi K, Hara M, Fukasawa C, Sugiura T, Nishimagi E, Harigai M, Kamatani N.
    Arthritis Rheum; 2004 Jan; 50(1):216-26. PubMed ID: 14730619
    [Abstract] [Full Text] [Related]

  • 13. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma.
    Ghosh AK, Bhattacharyya S, Lakos G, Chen SJ, Mori Y, Varga J.
    Arthritis Rheum; 2004 Apr; 50(4):1305-18. PubMed ID: 15077315
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.
    Avouac J, Palumbo K, Tomcik M, Zerr P, Dees C, Horn A, Maurer B, Akhmetshina A, Beyer C, Sadowski A, Schneider H, Shiozawa S, Distler O, Schett G, Allanore Y, Distler JH.
    Arthritis Rheum; 2012 May; 64(5):1642-52. PubMed ID: 22139817
    [Abstract] [Full Text] [Related]

  • 15. MicroRNA-29, a key regulator of collagen expression in systemic sclerosis.
    Maurer B, Stanczyk J, Jüngel A, Akhmetshina A, Trenkmann M, Brock M, Kowal-Bielecka O, Gay RE, Michel BA, Distler JH, Gay S, Distler O.
    Arthritis Rheum; 2010 Jun; 62(6):1733-43. PubMed ID: 20201077
    [Abstract] [Full Text] [Related]

  • 16. Role of apoptosis and transforming growth factor beta1 in fibroblast selection and activation in systemic sclerosis.
    Jelaska A, Korn JH.
    Arthritis Rheum; 2000 Oct; 43(10):2230-9. PubMed ID: 11037882
    [Abstract] [Full Text] [Related]

  • 17. Collagen type I is not under autocrine control by transforming growth factor-beta 1 in normal and scleroderma fibroblasts.
    McWhirter A, Colosetti P, Rubin K, Miyazono K, Black C.
    Lab Invest; 1994 Dec; 71(6):885-94. PubMed ID: 7807970
    [Abstract] [Full Text] [Related]

  • 18. Expression of osteonectin, decorin, and transforming growth factor-beta 1 genes in fibroblasts cultured from patients with systemic sclerosis and morphea.
    Vuorio T, Kähäri VM, Black C, Vuorio E.
    J Rheumatol; 1991 Feb; 18(2):247-51. PubMed ID: 2023219
    [Abstract] [Full Text] [Related]

  • 19. Involvement of the constitutive complex formation of c-Ski/SnoN with Smads in the impaired negative feedback regulation of transforming growth factor beta signaling in scleroderma fibroblasts.
    Jinnin M, Ihn H, Mimura Y, Asano Y, Tamaki K.
    Arthritis Rheum; 2007 May; 56(5):1694-705. PubMed ID: 17469184
    [Abstract] [Full Text] [Related]

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