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Journal Abstract Search

118 related items for PubMed ID: 11248150

  • 1. Short-Term (13-week) toxicity study of 5-bromo-6-methoxy-5,6-dihydro-3'-azidothymidine-5'-(p-bromophenyl) methoxyalaninyl phosphate (WHI-07), a novel anti-HIV and contraceptive agent, in B6C3F1 mice.
    D'Cruz OJ, Uckun FM.
    Toxicol Sci; 2001 Apr; 60(2):373-8. PubMed ID: 11248150
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  • 5. Evaluation of subchronic (13 weeks) and reproductive toxicity potential of intravaginal gel-microemulsion formulation of a dual-function phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-05) in B(6)C(3)F(1) mice.
    D'Cruz OJ, Waurzyniak B, Yiv SH, Uckun FM.
    Contraception; 2000 Jan; 61(1):69-76. PubMed ID: 10745072
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  • 6. Developmental toxicology studies of WHI-07, a novel nucleoside analogue-based dual-function microbicide, administered intravaginally to rabbits.
    D'Cruz OJ, Erbeck D, Uckun FM.
    Toxicol Pathol; 2003 Jan; 31(6):698-708. PubMed ID: 14585739
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  • 7. Preclinical evaluation of a dual-acting microbicidal prodrug WHI-07 in combination with vanadocene dithiocarbamate in the female reproductive tract of rabbit, pig, and cat.
    D'Cruz OJ, Uckun FM.
    Toxicol Pathol; 2007 Dec; 35(7):910-27. PubMed ID: 18098038
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  • 8. Pre-clinical safety evaluation of novel nucleoside analogue-based dual-function microbicides (WHI-05 and WHI-07).
    D'Cruz OJ, Uckun FM.
    J Antimicrob Chemother; 2002 Dec; 50(6):793-803. PubMed ID: 12460996
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  • 11. WHI-05, a novel bromo-methoxy substituted phenyl phosphate derivative of zidovudine, is a dual-action spermicide with potent anti-HIV activity.
    D'Cruz OJ, Zhu Z, Yiv SH, Chen CL, Waurzyniak B, Uckun FM.
    Contraception; 1999 May; 59(5):319-31. PubMed ID: 10494486
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  • 12. Evaluation of local tolerance of the antiretroviral spermicide (WHI-07)-loaded gel-microemulsion in the porcine female reproductive tract.
    D'Cruz OJ, Uckun FM.
    J Appl Toxicol; 2008 Apr; 28(3):303-14. PubMed ID: 17624922
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  • 13. Synthesis, characterization and preclinical formulation of a dual-action phenyl phosphate derivative of bromo-methoxy zidovudine (compound WHI-07) with potent anti-HIV and spermicidal activities.
    D'Cruz OJ, Shih MJ, Yiv SH, Chen CL, Uckun FM.
    Mol Hum Reprod; 1999 May; 5(5):421-32. PubMed ID: 10338365
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  • 15. Aryl phosphate derivatives of bromo-methoxy-azidothymidine are dual-function spermicides with potent anti-human immunodeficiency virus.
    D'Cruz OJ, Venkatachalam TK, Zhu Z, Shih MJ, Uckun FM.
    Biol Reprod; 1998 Sep; 59(3):503-15. PubMed ID: 9716547
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  • 16. Subchronic (13-week) toxicity studies of intravaginal administration of spermicidal vanadocene acetylacetonato monotriflate in mice.
    D'Cruz OJ, Waurzyniak B, Uckun FM.
    Toxicology; 2002 Jan 15; 170(1-2):31-43. PubMed ID: 11750081
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  • 17. Antiretroviral spermicide WHI-07 prevents vaginal and rectal transmission of feline immunodeficiency virus in domestic cats.
    D'Cruz OJ, Waurzyniak B, Uckun FM.
    Antimicrob Agents Chemother; 2004 Apr 15; 48(4):1082-8. PubMed ID: 15047505
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  • 19. Subchronic (13-week) toxicity studies of intravaginal administration of spermicidal vanadocene dithiocarbamate in mice.
    D'Cruz OJ, Waurzyniak B, Uckun FM.
    Contraception; 2001 Sep 15; 64(3):177-85. PubMed ID: 11704098
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  • 20. Thymidine kinase-independent intracellular delivery of bioactive nucleotides by aryl phosphate derivatives of bromo-methoxy zidovudine (compounds WHI-05 and WHI-07) in normal human female genital tract epithelial cells and sperm.
    D'Cruz OJ, Venkatachalam TK, Uckun FM.
    Biol Reprod; 2001 Jan 15; 64(1):51-9. PubMed ID: 11133658
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