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Journal Abstract Search


124 related items for PubMed ID: 11248688

  • 1. Drug transport by reconstituted P-glycoprotein in proteoliposomes. Effect of substrates and modulators, and dependence on bilayer phase state.
    Lu P, Liu R, Sharom FJ.
    Eur J Biochem; 2001 Mar; 268(6):1687-97. PubMed ID: 11248688
    [Abstract] [Full Text] [Related]

  • 2. Lipid bilayer properties control membrane partitioning, binding, and transport of p-glycoprotein substrates.
    Clay AT, Sharom FJ.
    Biochemistry; 2013 Jan 15; 52(2):343-54. PubMed ID: 23268645
    [Abstract] [Full Text] [Related]

  • 3. The mechanism of ATP-dependent multidrug transport by P-glycoprotein.
    Shapiro AB, Ling V.
    Acta Physiol Scand Suppl; 1998 Aug 15; 643():227-34. PubMed ID: 9789565
    [Abstract] [Full Text] [Related]

  • 4. The reconstituted P-glycoprotein multidrug transporter is a flippase for glucosylceramide and other simple glycosphingolipids.
    Eckford PD, Sharom FJ.
    Biochem J; 2005 Jul 15; 389(Pt 2):517-26. PubMed ID: 15799713
    [Abstract] [Full Text] [Related]

  • 5. Transition state P-glycoprotein binds drugs and modulators with unchanged affinity, suggesting a concerted transport mechanism.
    Qu Q, Chu JW, Sharom FJ.
    Biochemistry; 2003 Feb 11; 42(5):1345-53. PubMed ID: 12564938
    [Abstract] [Full Text] [Related]

  • 6. Interaction of the P-glycoprotein multidrug efflux pump with cholesterol: effects on ATPase activity, drug binding and transport.
    Eckford PD, Sharom FJ.
    Biochemistry; 2008 Dec 23; 47(51):13686-98. PubMed ID: 19049391
    [Abstract] [Full Text] [Related]

  • 7. The membrane lipid environment modulates drug interactions with the P-glycoprotein multidrug transporter.
    Romsicki Y, Sharom FJ.
    Biochemistry; 1999 May 25; 38(21):6887-96. PubMed ID: 10346910
    [Abstract] [Full Text] [Related]

  • 8. Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter.
    Romsicki Y, Sharom FJ.
    Biochemistry; 2001 Jun 12; 40(23):6937-47. PubMed ID: 11389609
    [Abstract] [Full Text] [Related]

  • 9. Interaction of insecticides with mammalian P-glycoprotein and their effect on its transport function.
    Sreeramulu K, Liu R, Sharom FJ.
    Biochim Biophys Acta; 2007 Jul 12; 1768(7):1750-7. PubMed ID: 17490606
    [Abstract] [Full Text] [Related]

  • 10. Reconstitution and functional studies of hamster P-glycoprotein in giant liposomes.
    Park S, Majd S.
    PLoS One; 2018 Jul 12; 13(6):e0199279. PubMed ID: 29912971
    [Abstract] [Full Text] [Related]

  • 11. Characterization of multidrug resistance P-glycoprotein transport function with an organotechnetium cation.
    Piwnica-Worms D, Rao VV, Kronauge JF, Croop JM.
    Biochemistry; 1995 Sep 26; 34(38):12210-20. PubMed ID: 7547962
    [Abstract] [Full Text] [Related]

  • 12. Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state.
    Ramachandra M, Ambudkar SV, Chen D, Hrycyna CA, Dey S, Gottesman MM, Pastan I.
    Biochemistry; 1998 Apr 07; 37(14):5010-9. PubMed ID: 9538020
    [Abstract] [Full Text] [Related]

  • 13. ATP occlusion by P-glycoprotein as a surrogate measure for drug coupling.
    Tombline G, Holt JJ, Gannon MK, Donnelly DJ, Wetzel B, Sawada GA, Raub TJ, Detty MR.
    Biochemistry; 2008 Mar 11; 47(10):3294-307. PubMed ID: 18275155
    [Abstract] [Full Text] [Related]

  • 14. Modulator-induced interference in functional cross talk between the substrate and the ATP sites of human P-glycoprotein.
    Maki N, Moitra K, Silver C, Ghosh P, Chattopadhyay A, Dey S.
    Biochemistry; 2006 Feb 28; 45(8):2739-51. PubMed ID: 16489767
    [Abstract] [Full Text] [Related]

  • 15. Stimulation of P-glycoprotein ATPase by analogues of tetramethylrosamine: coupling of drug binding at the "R" site to the ATP hydrolysis transition state.
    Tombline G, Donnelly DJ, Holt JJ, You Y, Ye M, Gannon MK, Nygren CL, Detty MR.
    Biochemistry; 2006 Jul 04; 45(26):8034-47. PubMed ID: 16800628
    [Abstract] [Full Text] [Related]

  • 16. Synthetic hydrophobic peptides are substrates for P-glycoprotein and stimulate drug transport.
    Sharom FJ, Yu X, DiDiodato G, Chu JW.
    Biochem J; 1996 Dec 01; 320 ( Pt 2)(Pt 2):421-8. PubMed ID: 8973548
    [Abstract] [Full Text] [Related]

  • 17. Catalytic mechanism of P-glycoprotein.
    Senior AE.
    Acta Physiol Scand Suppl; 1998 Aug 01; 643():213-8. PubMed ID: 9789563
    [Abstract] [Full Text] [Related]

  • 18. The ATPase and ATP-binding functions of P-glycoprotein--modulation by interaction with defined phospholipids.
    Romsicki Y, Sharom FJ.
    Eur J Biochem; 1998 Aug 15; 256(1):170-8. PubMed ID: 9746361
    [Abstract] [Full Text] [Related]

  • 19. Interaction of P-glycoprotein with defined phospholipid bilayers: a differential scanning calorimetric study.
    Romsicki Y, Sharom FJ.
    Biochemistry; 1997 Aug 12; 36(32):9807-15. PubMed ID: 9245413
    [Abstract] [Full Text] [Related]

  • 20. P-glycoprotein (ABCB1) interacts directly with lipid-based anti-cancer drugs and platelet-activating factors.
    Eckford PD, Sharom FJ.
    Biochem Cell Biol; 2006 Dec 12; 84(6):1022-33. PubMed ID: 17215888
    [Abstract] [Full Text] [Related]


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