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306 related items for PubMed ID: 11259561

  • 1. General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility.
    Krasowski MD, Jenkins A, Flood P, Kung AY, Hopfinger AJ, Harrison NL.
    J Pharmacol Exp Ther; 2001 Apr; 297(1):338-51. PubMed ID: 11259561
    [Abstract] [Full Text] [Related]

  • 2. The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study.
    Pistis M, Belelli D, Peters JA, Lambert JJ.
    Br J Pharmacol; 1997 Dec; 122(8):1707-19. PubMed ID: 9422818
    [Abstract] [Full Text] [Related]

  • 3. Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol.
    Watt EE, Betts BA, Kotey FO, Humbert DJ, Griffith TN, Kelly EW, Veneskey KC, Gill N, Rowan KC, Jenkins A, Hall AC.
    Eur J Pharmacol; 2008 Aug 20; 590(1-3):120-6. PubMed ID: 18593637
    [Abstract] [Full Text] [Related]

  • 4. Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor.
    Hill-Venning C, Belelli D, Peters JA, Lambert JJ.
    Br J Pharmacol; 1997 Mar 20; 120(5):749-56. PubMed ID: 9138677
    [Abstract] [Full Text] [Related]

  • 5. Modulation of the GABAA receptor by propofol is independent of the gamma subunit.
    Jones MV, Harrison NL, Pritchett DB, Hales TG.
    J Pharmacol Exp Ther; 1995 Aug 20; 274(2):962-8. PubMed ID: 7636760
    [Abstract] [Full Text] [Related]

  • 6. The anesthetic-like effects of diverse compounds on wild-type and mutant gamma-aminobutyric acid type A and glycine receptors.
    Yang L, Sonner JM.
    Anesth Analg; 2008 Mar 20; 106(3):838-45, table of contents. PubMed ID: 18292428
    [Abstract] [Full Text] [Related]

  • 7. Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital.
    Sanna E, Garau F, Harris RA.
    Mol Pharmacol; 1995 Feb 20; 47(2):213-7. PubMed ID: 7870027
    [Abstract] [Full Text] [Related]

  • 8. General anesthetics potentiate gamma-aminobutyric acid actions on gamma-aminobutyric acidA receptors expressed by Xenopus oocytes: lack of involvement of intracellular calcium.
    Lin LH, Chen LL, Zirrolli JA, Harris RA.
    J Pharmacol Exp Ther; 1992 Nov 20; 263(2):569-78. PubMed ID: 1331405
    [Abstract] [Full Text] [Related]

  • 9. The non-anaesthetic propofol analogue 2,6-di-tert-butylphenol fails to modulate GABA(A) receptor function.
    Ahrens J, Leuwer M, de la Roche J, Foadi N, Krampfl K, Haeseler G.
    Pharmacology; 2009 Nov 20; 83(2):95-8. PubMed ID: 19065063
    [Abstract] [Full Text] [Related]

  • 10. Actions of the general anesthetic propofol on recombinant human GABAA receptors: influence of receptor subunits.
    Sanna E, Mascia MP, Klein RL, Whiting PJ, Biggio G, Harris RA.
    J Pharmacol Exp Ther; 1995 Jul 20; 274(1):353-60. PubMed ID: 7616420
    [Abstract] [Full Text] [Related]

  • 11. Enhancement of gamma-aminobutyric acidA receptor activity by alpha-chloralose.
    Garrett KM, Gan J.
    J Pharmacol Exp Ther; 1998 May 20; 285(2):680-6. PubMed ID: 9580613
    [Abstract] [Full Text] [Related]

  • 12. Potentiation of gamma-aminobutyric acid type A receptor-mediated chloride currents by novel halogenated compounds correlates with their abilities to induce general anesthesia.
    Mihic SJ, McQuilkin SJ, Eger EI, Ionescu P, Harris RA.
    Mol Pharmacol; 1994 Nov 20; 46(5):851-7. PubMed ID: 7969071
    [Abstract] [Full Text] [Related]

  • 13. Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
    Zeng CM, Manion BD, Benz A, Evers AS, Zorumski CF, Mennerick S, Covey DF.
    J Med Chem; 2005 Apr 21; 48(8):3051-9. PubMed ID: 15828844
    [Abstract] [Full Text] [Related]

  • 14. Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia.
    Lingamaneni R, Krasowski MD, Jenkins A, Truong T, Giunta AL, Blackbeer J, MacIver MB, Harrison NL, Hemmings HC.
    Anesthesiology; 2001 Jun 21; 94(6):1050-7. PubMed ID: 11465597
    [Abstract] [Full Text] [Related]

  • 15. A transmembrane residue influences the interaction of propofol with the strychnine-sensitive glycine alpha1 and alpha1beta receptor.
    Ahrens J, Leuwer M, Stachura S, Krampfl K, Belelli D, Lambert JJ, Haeseler G.
    Anesth Analg; 2008 Dec 21; 107(6):1875-83. PubMed ID: 19020133
    [Abstract] [Full Text] [Related]

  • 16. Defining the propofol binding site location on the GABAA receptor.
    Bali M, Akabas MH.
    Mol Pharmacol; 2004 Jan 21; 65(1):68-76. PubMed ID: 14722238
    [Abstract] [Full Text] [Related]

  • 17. Characterization of the electrophysiological and pharmacological effects of 4-iodo-2,6-diisopropylphenol, a propofol analogue devoid of sedative-anaesthetic properties.
    Sanna E, Motzo C, Usala M, Serra M, Dazzi L, Maciocco E, Trapani G, Latrofa A, Liso G, Biggio G.
    Br J Pharmacol; 1999 Mar 21; 126(6):1444-54. PubMed ID: 10217539
    [Abstract] [Full Text] [Related]

  • 18. A conserved tyrosine in the beta2 subunit M4 segment is a determinant of gamma-aminobutyric acid type A receptor sensitivity to propofol.
    Richardson JE, Garcia PS, O'Toole KK, Derry JM, Bell SV, Jenkins A.
    Anesthesiology; 2007 Sep 21; 107(3):412-8. PubMed ID: 17721243
    [Abstract] [Full Text] [Related]

  • 19. Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
    Mascia MP, Asproni B, Busonero F, Talani G, Maciocco E, Pau A, Cerri R, Sanna E, Biggio G.
    Eur J Pharmacol; 2005 Jun 15; 516(3):204-11. PubMed ID: 15967425
    [Abstract] [Full Text] [Related]

  • 20. Transmembrane residues define the action of isoflurane at the GABAA receptor alpha-3 subunit.
    Schofield CM, Harrison NL.
    Brain Res; 2005 Jan 25; 1032(1-2):30-5. PubMed ID: 15680938
    [Abstract] [Full Text] [Related]

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