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Journal Abstract Search


210 related items for PubMed ID: 11265772

  • 1. Cytotoxicity of antiosteosarcoma recombinant immunotoxins composed of TP-3 Fv fragments and a truncated Pseudomonas exotoxin A.
    Onda M, Olafsen T, Tsutsumi Y, Bruland OS, Pastan I.
    J Immunother; 2001; 24(2):144-50. PubMed ID: 11265772
    [Abstract] [Full Text] [Related]

  • 2. Cytotoxicity of Antiosteosarcoma Recombinant Immunotoxins Composed of TP-3 Fv Fragments and a Truncated Pseudomonas Exotoxin A.
    Onda M, Olafsen T, Tsutsumi Y, Bruland ØS ØS, Pastan I.
    J Immunother (1991); 2001 Mar; 24(2):144-150. PubMed ID: 11449071
    [Abstract] [Full Text] [Related]

  • 3. Characterization of B1(Fv)PE38 and B1(dsFv)PE38: single-chain and disulfide-stabilized Fv immunotoxins with increased activity that cause complete remissions of established human carcinoma xenografts in nude mice.
    Benhar I, Pastan I.
    Clin Cancer Res; 1995 Sep; 1(9):1023-9. PubMed ID: 9816075
    [Abstract] [Full Text] [Related]

  • 4. In vitro and in vivo cytotoxic activities of recombinant immunotoxin 8H9(Fv)-PE38 against breast cancer, osteosarcoma, and neuroblastoma.
    Onda M, Wang QC, Guo HF, Cheung NK, Pastan I.
    Cancer Res; 2004 Feb 15; 64(4):1419-24. PubMed ID: 14973056
    [Abstract] [Full Text] [Related]

  • 5. Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3.
    Benhar I, Pastan I.
    J Biol Chem; 1995 Oct 06; 270(40):23373-80. PubMed ID: 7559495
    [Abstract] [Full Text] [Related]

  • 6. Administration of disulfide-stabilized Fv-immunotoxins B1(dsFv)-PE38 and B3(dsFv)-PE38 by continuous infusion increases their efficacy in curing large tumor xenografts in nude mice.
    Benhar I, Reiter Y, Pai LH, Pastan I.
    Int J Cancer; 1995 Jul 28; 62(3):351-5. PubMed ID: 7628878
    [Abstract] [Full Text] [Related]

  • 7. Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity.
    Onda M, Nagata S, Tsutsumi Y, Vincent JJ, Wang Q, Kreitman RJ, Lee B, Pastan I.
    Cancer Res; 2001 Jul 01; 61(13):5070-7. PubMed ID: 11431343
    [Abstract] [Full Text] [Related]

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  • 9. Recombinant single-chain and disulfide-stabilized Fv-immunotoxins that cause complete regression of a human colon cancer xenograft in nude mice.
    Reiter Y, Wright AF, Tonge DW, Pastan I.
    Int J Cancer; 1996 Jul 03; 67(1):113-23. PubMed ID: 8690511
    [Abstract] [Full Text] [Related]

  • 10. Cytotoxic and antitumor activity of a recombinant immunotoxin composed of disulfide-stabilized anti-Tac Fv fragment and truncated Pseudomonas exotoxin.
    Reiter Y, Kreitman RJ, Brinkmann U, Pastan I.
    Int J Cancer; 1994 Jul 01; 58(1):142-9. PubMed ID: 8014011
    [Abstract] [Full Text] [Related]

  • 11. A recombinant immunotoxin that is active on prostate cancer cells and that is composed of the Fv region of monoclonal antibody PR1 and a truncated form of Pseudomonas exotoxin.
    Brinkmann U, Gallo M, Brinkmann E, Kunwar S, Pastan I.
    Proc Natl Acad Sci U S A; 1993 Jan 15; 90(2):547-51. PubMed ID: 8421689
    [Abstract] [Full Text] [Related]

  • 12. Novel anti-CD30 recombinant immunotoxins containing disulfide-stabilized Fv fragments.
    Nagata S, Onda M, Numata Y, Santora K, Beers R, Kreitman RJ, Pastan I.
    Clin Cancer Res; 2002 Jul 15; 8(7):2345-55. PubMed ID: 12114439
    [Abstract] [Full Text] [Related]

  • 13. Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv.
    Reiter Y, Brinkmann U, Webber KO, Jung SH, Lee B, Pastan I.
    Protein Eng; 1994 May 15; 7(5):697-704. PubMed ID: 8073039
    [Abstract] [Full Text] [Related]

  • 14. Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys.
    Kreitman RJ, Wang QC, FitzGerald DJ, Pastan I.
    Int J Cancer; 1999 Mar 31; 81(1):148-55. PubMed ID: 10077166
    [Abstract] [Full Text] [Related]

  • 15. Recombinant immunotoxins containing the VH or VL domain of monoclonal antibody B3 fused to Pseudomonas exotoxin.
    Brinkmann U, Lee BK, Pastan I.
    J Immunol; 1993 Apr 01; 150(7):2774-82. PubMed ID: 8454854
    [Abstract] [Full Text] [Related]

  • 16. [Construction, expression and functional characterization of disulfide-stabilized anti-hepatocarcinoma single chain Fv fused with truncated Pseudomonas exotoxin].
    Zhao J, Sun ZW, Liu YF, Yu WY.
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2003 Nov 01; 19(6):585-7. PubMed ID: 15182657
    [Abstract] [Full Text] [Related]

  • 17. Bivalent disulfide-stabilized fragment variable immunotoxin directed against mesotheliomas and ovarian cancer.
    Bera TK, Williams-Gould J, Beers R, Chowdhury P, Pastan I.
    Mol Cancer Ther; 2001 Dec 01; 1(2):79-84. PubMed ID: 12467225
    [Abstract] [Full Text] [Related]

  • 18. Characterization of the B cell epitopes associated with a truncated form of Pseudomonas exotoxin (PE38) used to make immunotoxins for the treatment of cancer patients.
    Onda M, Nagata S, FitzGerald DJ, Beers R, Fisher RJ, Vincent JJ, Lee B, Nakamura M, Hwang J, Kreitman RJ, Hassan R, Pastan I.
    J Immunol; 2006 Dec 15; 177(12):8822-34. PubMed ID: 17142785
    [Abstract] [Full Text] [Related]

  • 19. A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.
    Weldon JE, Xiang L, Chertov O, Margulies I, Kreitman RJ, FitzGerald DJ, Pastan I.
    Blood; 2009 Apr 16; 113(16):3792-800. PubMed ID: 18988862
    [Abstract] [Full Text] [Related]

  • 20. Design of a modular immunotoxin connected by polyionic adapter peptides.
    Kleinschmidt M, Rudolph R, Lilie H.
    J Mol Biol; 2003 Mar 21; 327(2):445-52. PubMed ID: 12628249
    [Abstract] [Full Text] [Related]


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