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391 related items for PubMed ID: 11278771

  • 1. Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway.
    Gupta S, Stravitz RT, Dent P, Hylemon PB.
    J Biol Chem; 2001 May 11; 276(19):15816-22. PubMed ID: 11278771
    [Abstract] [Full Text] [Related]

  • 2. Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids.
    Chen W, Owsley E, Yang Y, Stroup D, Chiang JY.
    J Lipid Res; 2001 Sep 11; 42(9):1402-12. PubMed ID: 11518759
    [Abstract] [Full Text] [Related]

  • 3. Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation.
    Gupta S, Natarajan R, Payne SG, Studer EJ, Spiegel S, Dent P, Hylemon PB.
    J Biol Chem; 2004 Feb 13; 279(7):5821-8. PubMed ID: 14660582
    [Abstract] [Full Text] [Related]

  • 4. The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors.
    De Fabiani E, Mitro N, Anzulovich AC, Pinelli A, Galli G, Crestani M.
    J Biol Chem; 2001 Aug 17; 276(33):30708-16. PubMed ID: 11402042
    [Abstract] [Full Text] [Related]

  • 5. Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells.
    Li T, Jahan A, Chiang JY.
    Hepatology; 2006 Jun 17; 43(6):1202-10. PubMed ID: 16729332
    [Abstract] [Full Text] [Related]

  • 6. A GAPDH-mediated trans-nitrosylation pathway is required for feedback inhibition of bile salt synthesis in rat liver.
    Rodríguez-Ortigosa CM, Celay J, Olivas I, Juanarena N, Arcelus S, Uriarte I, Marín JJ, Avila MA, Medina JF, Prieto J.
    Gastroenterology; 2014 Nov 17; 147(5):1084-93. PubMed ID: 25066374
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  • 7. Mechanisms for increased expression of cholesterol 7alpha-hydroxylase (Cyp7a1) in lactating rats.
    Wooton-Kee CR, Coy DJ, Athippozhy AT, Zhao T, Jones BR, Vore M.
    Hepatology; 2010 Jan 17; 51(1):277-85. PubMed ID: 19957370
    [Abstract] [Full Text] [Related]

  • 8. Suppression of cholesterol 7alpha-hydroxylase transcription and bile acid synthesis by an alpha1-antitrypsin peptide via interaction with alpha1-fetoprotein transcription factor.
    Gerbod-Giannone MC, Del Castillo-Olivares A, Janciauskiene S, Gil G, Hylemon PB.
    J Biol Chem; 2002 Nov 08; 277(45):42973-80. PubMed ID: 12223476
    [Abstract] [Full Text] [Related]

  • 9. Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids.
    Bramlett KS, Yao S, Burris TP.
    Mol Genet Metab; 2000 Dec 08; 71(4):609-15. PubMed ID: 11136553
    [Abstract] [Full Text] [Related]

  • 10. On the mechanism of bile acid inhibition of rat sterol 12alpha-hydroxylase gene (CYP8B1) transcription: roles of alpha-fetoprotein transcription factor and hepatocyte nuclear factor 4alpha.
    Yang Y, Zhang M, Eggertsen G, Chiang JY.
    Biochim Biophys Acta; 2002 Jun 13; 1583(1):63-73. PubMed ID: 12069850
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  • 12. Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene.
    Jahan A, Chiang JY.
    Am J Physiol Gastrointest Liver Physiol; 2005 Apr 13; 288(4):G685-95. PubMed ID: 15550563
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  • 14. Transcriptional regulation of heme oxygenase-1 gene expression by MAP kinases of the JNK and p38 pathways in primary cultures of rat hepatocytes.
    Kietzmann T, Samoylenko A, Immenschuh S.
    J Biol Chem; 2003 May 16; 278(20):17927-36. PubMed ID: 12637567
    [Abstract] [Full Text] [Related]

  • 15. Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis.
    Song KH, Chiang JY.
    Hepatology; 2006 Jan 16; 43(1):117-25. PubMed ID: 16323215
    [Abstract] [Full Text] [Related]

  • 16. Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms.
    Cai SY, He H, Nguyen T, Mennone A, Boyer JL.
    J Lipid Res; 2010 Aug 16; 51(8):2265-74. PubMed ID: 20338915
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  • 19. Transcriptional regulation of cholesterol 7 alpha-hydroxylase mRNA by conjugated bile acids in primary cultures of rat hepatocytes.
    Stravitz RT, Hylemon PB, Heuman DM, Hagey LR, Schteingart CD, Ton-Nu HT, Hofmann AF, Vlahcevic ZR.
    J Biol Chem; 1993 Jul 05; 268(19):13987-93. PubMed ID: 8314765
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