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Journal Abstract Search


436 related items for PubMed ID: 11287661

  • 1. An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen.
    Chan K, Han XD, Kan YW.
    Proc Natl Acad Sci U S A; 2001 Apr 10; 98(8):4611-6. PubMed ID: 11287661
    [Abstract] [Full Text] [Related]

  • 2. High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes.
    Enomoto A, Itoh K, Nagayoshi E, Haruta J, Kimura T, O'Connor T, Harada T, Yamamoto M.
    Toxicol Sci; 2001 Jan 10; 59(1):169-77. PubMed ID: 11134556
    [Abstract] [Full Text] [Related]

  • 3. Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2.
    Aleksunes LM, Slitt AL, Maher JM, Augustine LM, Goedken MJ, Chan JY, Cherrington NJ, Klaassen CD, Manautou JE.
    Toxicol Appl Pharmacol; 2008 Jan 01; 226(1):74-83. PubMed ID: 17935745
    [Abstract] [Full Text] [Related]

  • 4. Upregulation of Nrf2-related cytoprotective genes expression by acetaminophen-induced acute hepatotoxicity in mice and the protective role of betaine.
    Khodayar MJ, Kalantari H, Khorsandi L, Rashno M, Zeidooni L.
    Hum Exp Toxicol; 2020 Jul 01; 39(7):948-959. PubMed ID: 32081044
    [Abstract] [Full Text] [Related]

  • 5. Corilagin alleviates acetaminophen-induced hepatotoxicity via enhancing the AMPK/GSK3β-Nrf2 signaling pathway.
    Lv H, Hong L, Tian Y, Yin C, Zhu C, Feng H.
    Cell Commun Signal; 2019 Jan 10; 17(1):2. PubMed ID: 30630510
    [Abstract] [Full Text] [Related]

  • 6. Hepatoprotective Activity of Yellow Chinese Chive against Acetaminophen-Induced Acute Liver Injury via Nrf2 Signaling Pathway.
    Kawakami K, Moritani C, Hatanaka T, Suzaki E, Tsuboi S.
    J Nutr Sci Vitaminol (Tokyo); 2020 Jan 10; 66(4):357-363. PubMed ID: 32863309
    [Abstract] [Full Text] [Related]

  • 7. Protection afforded by pre- or post-treatment with 4-phenylbutyrate against liver injury induced by acetaminophen overdose in mice.
    Shimizu D, Ishitsuka Y, Miyata K, Tomishima Y, Kondo Y, Irikura M, Iwawaki T, Oike Y, Irie T.
    Pharmacol Res; 2014 Sep 10; 87():26-41. PubMed ID: 24951965
    [Abstract] [Full Text] [Related]

  • 8. Is nuclear factor erythroid 2-related factor 2 responsible for sex differences in susceptibility to acetaminophen-induced hepatotoxicity in mice?
    Rohrer PR, Rudraiah S, Goedken MJ, Manautou JE.
    Drug Metab Dispos; 2014 Oct 10; 42(10):1663-74. PubMed ID: 25092713
    [Abstract] [Full Text] [Related]

  • 9. Allyl methyl trisulfide protected against acetaminophen (paracetamol)-induced hepatotoxicity by suppressing CYP2E1 and activating Nrf2 in mouse liver.
    Zhao HJ, Li MJ, Zhang MP, Wei MK, Shen LP, Jiang M, Zeng T.
    Food Funct; 2019 Apr 01; 10(4):2244-2253. PubMed ID: 30958500
    [Abstract] [Full Text] [Related]

  • 10. Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice.
    Randle LE, Goldring CE, Benson CA, Metcalfe PN, Kitteringham NR, Park BK, Williams DP.
    Toxicology; 2008 Jan 20; 243(3):249-60. PubMed ID: 18078705
    [Abstract] [Full Text] [Related]

  • 11. Distinct roles of NF-kappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity.
    Dambach DM, Durham SK, Laskin JD, Laskin DL.
    Toxicol Appl Pharmacol; 2006 Mar 01; 211(2):157-65. PubMed ID: 16081117
    [Abstract] [Full Text] [Related]

  • 12. Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
    Ning C, Gao X, Wang C, Kong Y, Liu Z, Sun H, Sun P, Huo X, Ma X, Meng Q, Liu K.
    Regul Toxicol Pharmacol; 2018 Oct 01; 98():58-68. PubMed ID: 30030101
    [Abstract] [Full Text] [Related]

  • 13. Carbon monoxide releasing molecule A-1 attenuates acetaminophen-mediated hepatotoxicity and improves survival of mice by induction of Nrf2 and related genes.
    Upadhyay KK, Jadeja RN, Thadani JM, Joshi A, Vohra A, Mevada V, Patel R, Khurana S, Devkar RV.
    Toxicol Appl Pharmacol; 2018 Dec 01; 360():99-108. PubMed ID: 30273691
    [Abstract] [Full Text] [Related]

  • 14. Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway.
    Jiang YM, Wang Y, Tan HS, Yu T, Fan XM, Chen P, Zeng H, Huang M, Bi HC.
    Acta Pharmacol Sin; 2016 Mar 01; 37(3):382-9. PubMed ID: 26806302
    [Abstract] [Full Text] [Related]

  • 15. Nicotinic Acid against Acetaminophen-Induced Hepatotoxicity via Sirt1/Nrf2 Antioxidative Pathway in Mice.
    Hu D, Zhang L, Jiang R, Liao C, Xu J, Jiang S, Yang Y, Lin L, Huang J, Shen Y, Tang L, Li L.
    J Nutr Sci Vitaminol (Tokyo); 2021 Mar 01; 67(3):145-152. PubMed ID: 34193673
    [Abstract] [Full Text] [Related]

  • 16. N-acetylcysteine amide, a promising antidote for acetaminophen toxicity.
    Khayyat A, Tobwala S, Hart M, Ercal N.
    Toxicol Lett; 2016 Jan 22; 241():133-42. PubMed ID: 26602168
    [Abstract] [Full Text] [Related]

  • 17. Hepatic hypoxia-inducible factors inhibit PPARα expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity.
    Li D, Du Y, Yuan X, Han X, Dong Z, Chen X, Wu H, Zhang J, Xu L, Han C, Zhang M, Xia Q.
    Free Radic Biol Med; 2017 Sep 22; 110():102-116. PubMed ID: 28583670
    [Abstract] [Full Text] [Related]

  • 18. Tanshinone IIA protects against acetaminophen-induced hepatotoxicity via activating the Nrf2 pathway.
    Wang W, Guan C, Sun X, Zhao Z, Li J, Fu X, Qiu Y, Huang M, Jin J, Huang Z.
    Phytomedicine; 2016 Jun 01; 23(6):589-96. PubMed ID: 27161400
    [Abstract] [Full Text] [Related]

  • 19. Natural Polyphenol Chlorogenic Acid Protects Against Acetaminophen-Induced Hepatotoxicity by Activating ERK/Nrf2 Antioxidative Pathway.
    Wei M, Zheng Z, Shi L, Jin Y, Ji L.
    Toxicol Sci; 2018 Mar 01; 162(1):99-112. PubMed ID: 29136249
    [Abstract] [Full Text] [Related]

  • 20. Limonin ameliorates acetaminophen-induced hepatotoxicity by activating Nrf2 antioxidative pathway and inhibiting NF-κB inflammatory response via upregulating Sirt1.
    Yang R, Song C, Chen J, Zhou L, Jiang X, Cao X, Sun Y, Zhang Q.
    Phytomedicine; 2020 Apr 01; 69():153211. PubMed ID: 32259676
    [Abstract] [Full Text] [Related]


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