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333 related items for PubMed ID: 11295428

  • 1. New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey.
    Sandell J, Halldin C, Pike VW, Chou YH, Varnäs K, Hall H, Marchais S, Nowicki B, Wikström HV, Swahn CG, Farde L.
    Nucl Med Biol; 2001 Feb; 28(2):177-85. PubMed ID: 11295428
    [Abstract] [Full Text] [Related]

  • 2. Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635--explanation of high signal contrast in PET and an aid to biomathematical modelling.
    Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Farde L, Ginovart N, Luthra SK, Gunn RN, Bench CJ, Sargent PA, Grasby PM.
    Nucl Med Biol; 1998 Apr; 25(3):215-23. PubMed ID: 9620626
    [Abstract] [Full Text] [Related]

  • 3. [carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT1A receptors in vitro and in vivo.
    Pike VW, Halldin C, McCarron JA, Lundkvist C, Hirani E, Olsson H, Hume SP, Karlsson P, Osman S, Swahn CG, Hall H, Wikström H, Mensonidas M, Poole KG, Farde L.
    Eur J Nucl Med; 1998 Apr; 25(4):338-46. PubMed ID: 9553162
    [Abstract] [Full Text] [Related]

  • 4. The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain.
    Andrée B, Halldin C, Pike VW, Gunn RN, Olsson H, Farde L.
    J Nucl Med; 2002 Mar; 43(3):292-303. PubMed ID: 11884487
    [Abstract] [Full Text] [Related]

  • 5. The pyridinyl-6 position of WAY-100635 as a site for radiofluorination--effect on 5-HT1A receptor radioligand behavior in vivo.
    McCarron JA, Pike VW, Halldin C, Sandell J, Sóvágó J, Gulyas B, Cselényi Z, Wikström HV, Marchais-Oberwinkler S, Nowicki B, Dollé F, Farde L.
    Mol Imaging Biol; 2004 Mar; 6(1):17-26. PubMed ID: 15018825
    [Abstract] [Full Text] [Related]

  • 6. Characterization of the radioactive metabolites of the 5-HT1A receptor radioligand, [O-methyl-11C]WAY-100635, in monkey and human plasma by HPLC: comparison of the behaviour of an identified radioactive metabolite with parent radioligand in monkey using PET.
    Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Ginovart N, Luthra SK, Bench CJ, Grasby PM, Wikström H, Barf T, Cliffe IA, Fletcher A, Farde L.
    Nucl Med Biol; 1996 Jul; 23(5):627-34. PubMed ID: 8905828
    [Abstract] [Full Text] [Related]

  • 7. Quantitative analyses of carbonyl-carbon-11-WAY-100635 binding to central 5-hydroxytryptamine-1A receptors in man.
    Farde L, Ito H, Swahn CG, Pike VW, Halldin C.
    J Nucl Med; 1998 Nov; 39(11):1965-71. PubMed ID: 9829590
    [Abstract] [Full Text] [Related]

  • 8. Two C-methyl derivatives of [11C]WAY-100635--effects of an amido alpha-methyl group on metabolism and brain 5-HT1A receptor radioligand behavior in monkey.
    McCarron JA, Marchais-Oberwinkler S, Pike VW, Tarkiainen J, Halldin C, Sóvagó J, Gulyas B, Wikström HV, Farde L.
    Mol Imaging Biol; 2005 Nov; 7(3):209-19. PubMed ID: 15912425
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biologic evaluation of a novel serotonin 5-HT1A receptor radioligand, 18F-labeled mefway, in rodents and imaging by PET in a nonhuman primate.
    Saigal N, Pichika R, Easwaramoorthy B, Collins D, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J.
    J Nucl Med; 2006 Oct; 47(10):1697-706. PubMed ID: 17015907
    [Abstract] [Full Text] [Related]

  • 10. In vivo characterization of p-[(18)F]MPPF, a fluoro analog of WAY-100635 for visualization of 5-HT(1a) receptors.
    Ginovart N, Hassoun W, Le Bars D, Weissmann D, Leviel V.
    Synapse; 2000 Mar 01; 35(3):192-200. PubMed ID: 10657026
    [Abstract] [Full Text] [Related]

  • 11. Imaging 5-HT1A receptors with positron emission tomography: initial human studies with [11C]CPC-222.
    Houle S, Wilson AA, Inaba T, Fisher N, DaSilva JN.
    Nucl Med Commun; 1997 Dec 01; 18(12):1130-4. PubMed ID: 9481759
    [Abstract] [Full Text] [Related]

  • 12. Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635.
    Hall H, Lundkvist C, Halldin C, Farde L, Pike VW, McCarron JA, Fletcher A, Cliffe IA, Barf T, Wikström H, Sedvall G.
    Brain Res; 1997 Jan 16; 745(1-2):96-108. PubMed ID: 9037397
    [Abstract] [Full Text] [Related]

  • 13. N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists.
    Marchais-Oberwinkler S, Nowicki B, Pike VW, Halldin C, Sandell J, Chou YH, Gulyas B, Brennum LT, Farde L, Wikström HV.
    Bioorg Med Chem; 2005 Feb 01; 13(3):883-93. PubMed ID: 15653354
    [Abstract] [Full Text] [Related]

  • 14. PET-examination and metabolite evaluation in monkey of [(11)C]NAD-299, a radioligand for visualisation of the 5-HT(1A) receptor.
    Sandell J, Halldin C, Chou YH, Swahn CG, Thorberg SO, Farde L.
    Nucl Med Biol; 2002 Jan 01; 29(1):39-45. PubMed ID: 11786274
    [Abstract] [Full Text] [Related]

  • 15. Tissue distribution, autoradiography, and metabolism of 4-(2'-methoxyphenyl)-1-[2' -[N-2"-pyridinyl)-p-[(18)F]fluorobenzamido]ethyl]piperazine (p-[(18)F]MPPF), a new serotonin 5-HT(1A) antagonist for positron emission tomography: An In vivo study in rats.
    Plenevaux A, Weissmann D, Aerts J, Lemaire C, Brihaye C, Degueldre C, Le Bars D, Comar D, Pujol J, Luxen A.
    J Neurochem; 2000 Aug 01; 75(2):803-11. PubMed ID: 10899958
    [Abstract] [Full Text] [Related]

  • 16. Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11 C]WAY-100635.
    Pike VW, McCarron JA, Lammertsma AA, Osman S, Hume SP, Sargent PA, Bench CJ, Cliffe IA, Fletcher A, Grasby PM.
    Eur J Pharmacol; 1996 Apr 22; 301(1-3):R5-7. PubMed ID: 8773468
    [Abstract] [Full Text] [Related]

  • 17. In vivo binding of [123I]4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl)- p-iodobenzamido-]ethyl-piperazine, p-MPPI, to 5-HT1A receptors in rat brain.
    Kung MP, Zhuang ZP, Frederick D, Kung HF.
    Synapse; 1994 Dec 22; 18(4):359-66. PubMed ID: 7886629
    [Abstract] [Full Text] [Related]

  • 18. Quantification of 5-HT(1A) receptors in human brain using p-MPPF kinetic modelling and PET.
    Sanabria-Bohórquez SM, Biver F, Damhaut P, Wikler D, Veraart C, Goldman S.
    Eur J Nucl Med Mol Imaging; 2002 Jan 22; 29(1):76-81. PubMed ID: 11807610
    [Abstract] [Full Text] [Related]

  • 19. Effects of aging on 5-HT(1A) receptors and their functional response to 5-HT(1a) agonist in the living brain: PET study with [carbonyl-(11)C]WAY-100635 in conscious monkeys.
    Tsukada H, Kakiuchi T, Nishiyama S, Ohba H, Harada N.
    Synapse; 2001 Dec 15; 42(4):242-51. PubMed ID: 11746722
    [Abstract] [Full Text] [Related]

  • 20. Radiosynthesis and in vivo evaluation of novel radioligands for PET imaging of cerebral 5-HT7 receptors.
    Hansen HD, Herth MM, Ettrup A, Andersen VL, Lehel S, Dyssegaard A, Kristensen JL, Knudsen GM.
    J Nucl Med; 2014 Apr 15; 55(4):640-6. PubMed ID: 24566002
    [Abstract] [Full Text] [Related]

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