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Journal Abstract Search

1213 related items for PubMed ID: 11298070

  • 1. Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.
    Hyland R, Roe EG, Jones BC, Smith DA.
    Br J Clin Pharmacol; 2001 Mar; 51(3):239-48. PubMed ID: 11298070
    [Abstract] [Full Text] [Related]

  • 2. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K, von Moltke LL, Duan SX, Fleishaker JC, Shader RI, Greenblatt DJ.
    J Pharm Pharmacol; 1998 Mar; 50(3):265-74. PubMed ID: 9600717
    [Abstract] [Full Text] [Related]

  • 3. Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor.
    Tang C, Shou M, Mei Q, Rushmore TH, Rodrigues AD.
    J Pharmacol Exp Ther; 2000 May; 293(2):453-9. PubMed ID: 10773015
    [Abstract] [Full Text] [Related]

  • 4. Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid.
    Taguchi K, Konishi T, Nishikawa H, Kitamura S.
    Xenobiotica; 1999 Sep; 29(9):899-907. PubMed ID: 10548450
    [Abstract] [Full Text] [Related]

  • 5. Oxidation of cyclophosphamide to 4-hydroxycyclophosphamide and deschloroethylcyclophosphamide in human liver microsomes.
    Ren S, Yang JS, Kalhorn TF, Slattery JT.
    Cancer Res; 1997 Oct 01; 57(19):4229-35. PubMed ID: 9331082
    [Abstract] [Full Text] [Related]

  • 6. The role of CYP2C in the in vitro bioactivation of the contraceptive steroid desogestrel.
    Gentile DM, Verhoeven CH, Shimada T, Back DJ.
    J Pharmacol Exp Ther; 1998 Dec 01; 287(3):975-82. PubMed ID: 9864282
    [Abstract] [Full Text] [Related]

  • 7. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM, Murray M.
    J Pharmacol Exp Ther; 1997 Feb 01; 280(2):966-73. PubMed ID: 9023313
    [Abstract] [Full Text] [Related]

  • 8. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone.
    Baldwin SJ, Clarke SE, Chenery RJ.
    Br J Clin Pharmacol; 1999 Sep 01; 48(3):424-32. PubMed ID: 10510156
    [Abstract] [Full Text] [Related]

  • 9. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.
    Xenobiotica; 2000 Oct 01; 30(10):955-69. PubMed ID: 11315104
    [Abstract] [Full Text] [Related]

  • 10. Cytochrome P-450 enzymes and FMO3 contribute to the disposition of the antipsychotic drug perazine in vitro.
    Störmer E, Brockmöller J, Roots I, Schmider J.
    Psychopharmacology (Berl); 2000 Sep 01; 151(4):312-20. PubMed ID: 11026737
    [Abstract] [Full Text] [Related]

  • 11. In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
    Wen X, Wang JS, Kivistö KT, Neuvonen PJ, Backman JT.
    Br J Clin Pharmacol; 2001 Nov 01; 52(5):547-53. PubMed ID: 11736863
    [Abstract] [Full Text] [Related]

  • 12. Evidence for involvement of polymorphic CYP2C19 and 2C9 in the N-demethylation of sertraline in human liver microsomes.
    Xu ZH, Wang W, Zhao XJ, Huang SL, Zhu B, He N, Shu Y, Liu ZQ, Zhou HH.
    Br J Clin Pharmacol; 1999 Sep 01; 48(3):416-23. PubMed ID: 10510155
    [Abstract] [Full Text] [Related]

  • 13. Activation of phenacetin O-deethylase activity by alpha-naphthoflavone in human liver microsomes.
    Nakajima M, Kobayashi K, Oshima K, Shimada N, Tokudome S, Chiba K, Yokoi T.
    Xenobiotica; 1999 Sep 01; 29(9):885-98. PubMed ID: 10548449
    [Abstract] [Full Text] [Related]

  • 14. Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2.
    Ball SE, Ahern D, Scatina J, Kao J.
    Br J Clin Pharmacol; 1997 Jun 01; 43(6):619-26. PubMed ID: 9205822
    [Abstract] [Full Text] [Related]

  • 15. In vitro biotransformation of sildenafil (Viagra) in the male rat: the role of CYP2C11.
    Warrington JS, Von Moltke LL, Shader RI, Greenblatt DJ.
    Drug Metab Dispos; 2002 Jun 01; 30(6):655-7. PubMed ID: 12019191
    [Abstract] [Full Text] [Related]

  • 16. Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9.
    Wen X, Wang JS, Backman JT, Kivistö KT, Neuvonen PJ.
    Drug Metab Dispos; 2001 Nov 01; 29(11):1359-61. PubMed ID: 11602509
    [Abstract] [Full Text] [Related]

  • 17. In vitro metabolism of the calmodulin antagonist DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) by human liver microsomes: involvement of cytochromes p450 in atypical kinetics and potential drug interactions.
    Tachibana S, Fujimaki Y, Yokoyama H, Okazaki O, Sudo K.
    Drug Metab Dispos; 2005 Nov 01; 33(11):1628-36. PubMed ID: 16049129
    [Abstract] [Full Text] [Related]

  • 18. Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily.
    Rodrigues AD, Roberts EM, Mulford DJ, Yao Y, Ouellet D.
    Drug Metab Dispos; 1997 May 01; 25(5):623-30. PubMed ID: 9152603
    [Abstract] [Full Text] [Related]

  • 19. Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A.
    von Moltke LL, Greenblatt DJ, Grassi JM, Granda BW, Venkatakrishnan K, Schmider J, Harmatz JS, Shader RI.
    J Pharm Pharmacol; 1998 Sep 01; 50(9):997-1004. PubMed ID: 9811160
    [Abstract] [Full Text] [Related]

  • 20. Effects of propofol on human hepatic microsomal cytochrome P450 activities.
    McKillop D, Wild MJ, Butters CJ, Simcock C.
    Xenobiotica; 1998 Sep 01; 28(9):845-53. PubMed ID: 9764927
    [Abstract] [Full Text] [Related]

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