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Journal Abstract Search

796 related items for PubMed ID: 11298456

  • 1. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.
    Falck J, Mailand N, Syljuåsen RG, Bartek J, Lukas J.
    Nature; 2001 Apr 12; 410(6830):842-7. PubMed ID: 11298456
    [Abstract] [Full Text] [Related]

  • 2. Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.
    Sørensen CS, Syljuåsen RG, Falck J, Schroeder T, Rönnstrand L, Khanna KK, Zhou BB, Bartek J, Lukas J.
    Cancer Cell; 2003 Mar 12; 3(3):247-58. PubMed ID: 12676583
    [Abstract] [Full Text] [Related]

  • 3. The mismatch repair system is required for S-phase checkpoint activation.
    Brown KD, Rathi A, Kamath R, Beardsley DI, Zhan Q, Mannino JL, Baskaran R.
    Nat Genet; 2003 Jan 12; 33(1):80-4. PubMed ID: 12447371
    [Abstract] [Full Text] [Related]

  • 4. Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase.
    Jin J, Ang XL, Ye X, Livingstone M, Harper JW.
    J Biol Chem; 2008 Jul 11; 283(28):19322-8. PubMed ID: 18480045
    [Abstract] [Full Text] [Related]

  • 5. Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.
    Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK.
    J Biol Chem; 2003 Apr 25; 278(17):14806-11. PubMed ID: 12588868
    [Abstract] [Full Text] [Related]

  • 6. The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways.
    Falck J, Petrini JH, Williams BR, Lukas J, Bartek J.
    Nat Genet; 2002 Mar 25; 30(3):290-4. PubMed ID: 11850621
    [Abstract] [Full Text] [Related]

  • 7. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway.
    Chaturvedi P, Eng WK, Zhu Y, Mattern MR, Mishra R, Hurle MR, Zhang X, Annan RS, Lu Q, Faucette LF, Scott GF, Li X, Carr SA, Johnson RK, Winkler JD, Zhou BB.
    Oncogene; 1999 Jul 15; 18(28):4047-54. PubMed ID: 10435585
    [Abstract] [Full Text] [Related]

  • 8. DNA damage-induced degradation of Cdc25A does not lead to inhibition of Cdk2 activity in mouse embryonic stem cells.
    Koledova Z, Kafkova LR, Krämer A, Divoky V.
    Stem Cells; 2010 Mar 31; 28(3):450-61. PubMed ID: 20104581
    [Abstract] [Full Text] [Related]

  • 9. ATM regulates ATR chromatin loading in response to DNA double-strand breaks.
    Cuadrado M, Martinez-Pastor B, Murga M, Toledo LI, Gutierrez-Martinez P, Lopez E, Fernandez-Capetillo O.
    J Exp Med; 2006 Feb 20; 203(2):297-303. PubMed ID: 16461339
    [Abstract] [Full Text] [Related]

  • 10. Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity.
    Zhou BB, Chaturvedi P, Spring K, Scott SP, Johanson RA, Mishra R, Mattern MR, Winkler JD, Khanna KK.
    J Biol Chem; 2000 Apr 07; 275(14):10342-8. PubMed ID: 10744722
    [Abstract] [Full Text] [Related]

  • 11. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.
    Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.
    J Cell Sci; 2005 Apr 15; 118(Pt 8):1629-39. PubMed ID: 15784679
    [Abstract] [Full Text] [Related]

  • 12. Cell cycle. Checking two steps.
    Kastan MB.
    Nature; 2001 Apr 12; 410(6830):766-7. PubMed ID: 11298430
    [No Abstract] [Full Text] [Related]

  • 13. Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage.
    Bahassi el M, Myer DL, McKenney RJ, Hennigan RF, Stambrook PJ.
    Mutat Res; 2006 Apr 11; 596(1-2):166-76. PubMed ID: 16481012
    [Abstract] [Full Text] [Related]

  • 14. Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells.
    Agarwal C, Tyagi A, Agarwal R.
    Mol Cancer Ther; 2006 Dec 11; 5(12):3294-302. PubMed ID: 17172433
    [Abstract] [Full Text] [Related]

  • 15. Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1.
    Krause DR, Jonnalagadda JC, Gatei MH, Sillje HH, Zhou BB, Nigg EA, Khanna K.
    Oncogene; 2003 Sep 04; 22(38):5927-37. PubMed ID: 12955071
    [Abstract] [Full Text] [Related]

  • 16. SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.
    Jin J, Shirogane T, Xu L, Nalepa G, Qin J, Elledge SJ, Harper JW.
    Genes Dev; 2003 Dec 15; 17(24):3062-74. PubMed ID: 14681206
    [Abstract] [Full Text] [Related]

  • 17. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.
    Ouyang G, Yao L, Ruan K, Song G, Mao Y, Bao S.
    Cell Biol Int; 2009 Dec 15; 33(12):1237-44. PubMed ID: 19732843
    [Abstract] [Full Text] [Related]

  • 18. Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation.
    Ahn JY, Schwarz JK, Piwnica-Worms H, Canman CE.
    Cancer Res; 2000 Nov 01; 60(21):5934-6. PubMed ID: 11085506
    [Abstract] [Full Text] [Related]

  • 19. Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro.
    Matsuoka S, Rotman G, Ogawa A, Shiloh Y, Tamai K, Elledge SJ.
    Proc Natl Acad Sci U S A; 2000 Sep 12; 97(19):10389-94. PubMed ID: 10973490
    [Abstract] [Full Text] [Related]

  • 20. Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways.
    Gaul L, Mandl-Weber S, Baumann P, Emmerich B, Schmidmaier R.
    J Cancer Res Clin Oncol; 2008 Feb 12; 134(2):245-53. PubMed ID: 17653574
    [Abstract] [Full Text] [Related]

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