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137 related items for PubMed ID: 11300728

  • 1. Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice.
    Eckert A, Schindowski K, Leutner S, Luckhaus C, Touchet N, Czech C, Müller WE.
    Neurobiol Dis; 2001 Apr; 8(2):331-42. PubMed ID: 11300728
    [Abstract] [Full Text] [Related]

  • 2. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.
    J Neurosci Res; 2002 Aug 15; 69(4):530-9. PubMed ID: 12210846
    [Abstract] [Full Text] [Related]

  • 3. Abnormal intracellular trafficking of high affinity nerve growth factor receptor, Trk, in stable transfectants expressing presenilin 1 protein.
    Hamano T, Mutoh T, Tabira T, Araki W, Kuriyama M, Mihara T, Yano S, Yamamoto H.
    Brain Res Mol Brain Res; 2005 Jun 13; 137(1-2):70-6. PubMed ID: 15950763
    [Abstract] [Full Text] [Related]

  • 4. Regional brain metabolism with cytochrome c oxidase histochemistry in a PS1/A246E mouse model of autosomal dominant Alzheimer's disease: correlations with behavior and oxidative stress.
    Strazielle C, Jazi R, Verdier Y, Qian S, Lalonde R.
    Neurochem Int; 2009 Dec 13; 55(8):806-14. PubMed ID: 19682525
    [Abstract] [Full Text] [Related]

  • 5. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease.
    Mohmmad Abdul H, Sultana R, Keller JN, St Clair DK, Markesbery WR, Butterfield DA.
    J Neurochem; 2006 Mar 13; 96(5):1322-35. PubMed ID: 16478525
    [Abstract] [Full Text] [Related]

  • 6. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M.
    Nat Cell Biol; 1999 Dec 13; 1(8):479-85. PubMed ID: 10587643
    [Abstract] [Full Text] [Related]

  • 7. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.
    Wen PH, Hof PR, Chen X, Gluck K, Austin G, Younkin SG, Younkin LH, DeGasperi R, Gama Sosa MA, Robakis NK, Haroutunian V, Elder GA.
    Exp Neurol; 2004 Aug 13; 188(2):224-37. PubMed ID: 15246822
    [Abstract] [Full Text] [Related]

  • 8. APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.
    Jankowsky JL, Slunt HH, Gonzales V, Jenkins NA, Copeland NG, Borchelt DR.
    Neurobiol Aging; 2004 Aug 13; 25(7):885-92. PubMed ID: 15212842
    [Abstract] [Full Text] [Related]

  • 9. Functional phenotype in transgenic mice expressing mutant human presenilin-1.
    Barrow PA, Empson RM, Gladwell SJ, Anderson CM, Killick R, Yu X, Jefferys JG, Duff K.
    Neurobiol Dis; 2000 Apr 13; 7(2):119-26. PubMed ID: 10783295
    [Abstract] [Full Text] [Related]

  • 10. Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease.
    Smith IF, Hitt B, Green KN, Oddo S, LaFerla FM.
    J Neurochem; 2005 Sep 13; 94(6):1711-8. PubMed ID: 16156741
    [Abstract] [Full Text] [Related]

  • 11. Presenilin-1-deficient neurons are nitric oxide-dependently killed by hydrogen peroxide in vitro.
    Nakajima M, Shirasawa T.
    Neuroscience; 2004 Sep 13; 125(3):563-8. PubMed ID: 15099670
    [Abstract] [Full Text] [Related]

  • 12. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S, Counts SE, Ma SY, Dadko E, Gordon MN, Morgan D, Mufson EJ.
    Exp Neurol; 2001 Aug 13; 170(2):227-43. PubMed ID: 11476589
    [Abstract] [Full Text] [Related]

  • 13. Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis.
    Zhang Z, Hartmann H, Do VM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Sommer B, van de Wetering M, Clevers H, Saftig P, De Strooper B, He X, Yankner BA.
    Nature; 1998 Oct 15; 395(6703):698-702. PubMed ID: 9790190
    [Abstract] [Full Text] [Related]

  • 14. Altered cell cycle-related gene expression in brain and lymphocytes from a transgenic mouse model of Alzheimer's disease [amyloid precursor protein/presenilin 1 (PS1)].
    Esteras N, Bartolomé F, Alquézar C, Antequera D, Muñoz Ú, Carro E, Martín-Requero Á.
    Eur J Neurosci; 2012 Sep 15; 36(5):2609-18. PubMed ID: 22702220
    [Abstract] [Full Text] [Related]

  • 15. Decreased Abeta secretion by cells expressing familial Alzheimer's disease-linked mutant presenilin 1.
    Shimojo M, Sahara N, Murayama M, Ichinose H, Takashima A.
    Neurosci Res; 2007 Mar 15; 57(3):446-53. PubMed ID: 17210196
    [Abstract] [Full Text] [Related]

  • 16. Interaction of presenilins with FKBP38 promotes apoptosis by reducing mitochondrial Bcl-2.
    Wang HQ, Nakaya Y, Du Z, Yamane T, Shirane M, Kudo T, Takeda M, Takebayashi K, Noda Y, Nakayama KI, Nishimura M.
    Hum Mol Genet; 2005 Jul 01; 14(13):1889-902. PubMed ID: 15905180
    [Abstract] [Full Text] [Related]

  • 17. mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease.
    Lafay-Chebassier C, Paccalin M, Page G, Barc-Pain S, Perault-Pochat MC, Gil R, Pradier L, Hugon J.
    J Neurochem; 2005 Jul 01; 94(1):215-25. PubMed ID: 15953364
    [Abstract] [Full Text] [Related]

  • 18. Cell cycle-driven neuronal apoptosis specifically linked to amyloid peptide Abeta1-42 exposure is not exacerbated in a mouse model of presenilin-1 familial Alzheimer's disease.
    Malik B, Currais A, Soriano S.
    J Neurochem; 2008 Jul 01; 106(2):912-6. PubMed ID: 18466334
    [Abstract] [Full Text] [Related]

  • 19. Object recognition memory and cholinergic parameters in mice expressing human presenilin 1 transgenes.
    Vaucher E, Fluit P, Chishti MA, Westaway D, Mount HT, Kar S.
    Exp Neurol; 2002 Jun 01; 175(2):398-406. PubMed ID: 12061869
    [Abstract] [Full Text] [Related]

  • 20. Reelin-immunoreactivity in the hippocampal formation of 9-month-old wildtype mouse: effects of APP/PS1 genotype and ovariectomy.
    Miettinen R, Riedel A, Kalesnykas G, Kettunen HP, Puoliväli J, Soininen H, Arendt T.
    J Chem Neuroanat; 2005 Oct 01; 30(2-3):105-18. PubMed ID: 16081247
    [Abstract] [Full Text] [Related]


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