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Journal Abstract Search

203 related items for PubMed ID: 11304695

  • 1. Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways.
    Damia G, Silvestri S, Carrassa L, Filiberti L, Faircloth GT, Liberi G, Foiani M, D'Incalci M.
    Int J Cancer; 2001 May 15; 92(4):583-8. PubMed ID: 11304695
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  • 2. The inefficiency of incisions of ecteinascidin 743-DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair-dependent toxicities of this antitumor agent.
    Zewail-Foote M, Li VS, Kohn H, Bearss D, Guzman M, Hurley LH.
    Chem Biol; 2001 Nov 15; 8(11):1033-49. PubMed ID: 11731295
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  • 3. Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action.
    Erba E, Bergamaschi D, Bassano L, Damia G, Ronzoni S, Faircloth GT, D'Incalci M.
    Eur J Cancer; 2001 Jan 15; 37(1):97-105. PubMed ID: 11165136
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  • 4. Unique features of the mode of action of ET-743.
    D'Incalci M, Erba E, Damia G, Galliera E, Carrassa L, Marchini S, Mantovani R, Tognon G, Fruscio R, Jimeno J, Faircloth GT.
    Oncologist; 2002 Jan 15; 7(3):210-6. PubMed ID: 12065793
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  • 5. Role of homologous recombination in trabectedin-induced DNA damage.
    Tavecchio M, Simone M, Erba E, Chiolo I, Liberi G, Foiani M, D'Incalci M, Damia G.
    Eur J Cancer; 2008 Mar 15; 44(4):609-18. PubMed ID: 18243687
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  • 6. Poisoning of human DNA topoisomerase I by ecteinascidin 743, an anticancer drug that selectively alkylates DNA in the minor groove.
    Takebayashi Y, Pourquier P, Yoshida A, Kohlhagen G, Pommier Y.
    Proc Natl Acad Sci U S A; 1999 Jun 22; 96(13):7196-201. PubMed ID: 10377391
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  • 7. Ecteinascidin 743 induces protein-linked DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression.
    Takebayashi Y, Goldwasser F, Urasaki Y, Kohlhagen G, Pommier Y.
    Clin Cancer Res; 2001 Jan 22; 7(1):185-91. PubMed ID: 11205907
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  • 8. Preclinical and clinical results with the natural marine product ET-743.
    D'Incalci M, Jimeno J.
    Expert Opin Investig Drugs; 2003 Nov 22; 12(11):1843-53. PubMed ID: 14585059
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  • 12. Overcoming multidrug drug resistance in P-glycoprotein/MDR1-overexpressing cell lines by ecteinascidin 743.
    Kanzaki A, Takebayashi Y, Ren XQ, Miyashita H, Mori S, Akiyama S, Pommier Y.
    Mol Cancer Ther; 2002 Dec 22; 1(14):1327-34. PubMed ID: 12516966
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  • 15. Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743.
    Minuzzo M, Marchini S, Broggini M, Faircloth G, D'Incalci M, Mantovani R.
    Proc Natl Acad Sci U S A; 2000 Jun 06; 97(12):6780-4. PubMed ID: 10841573
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  • 16. Ecteinascidin 743: a novel anticancer drug with a unique mechanism of action.
    Aune GJ, Furuta T, Pommier Y.
    Anticancer Drugs; 2002 Jul 06; 13(6):545-55. PubMed ID: 12172500
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  • 17. In vitro antitumor activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients.
    Izbicka E, Lawrence R, Raymond E, Eckhardt G, Faircloth G, Jimeno J, Clark G, Von Hoff DD.
    Ann Oncol; 1998 Sep 06; 9(9):981-7. PubMed ID: 9818072
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  • 19. The unique biological features of the marine product Yondelis (ET-743, trabectedin) are shared by its analog ET-637, which lacks the C ring.
    Erba E, Cavallaro E, Damia G, Mantovani R, Di Silvio A, Di Francesco AM, Riccardi R, Cuevas C, Faircloth GT, D'Incalci M.
    Oncol Res; 2004 Sep 06; 14(11-12):579-87. PubMed ID: 15666999
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