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468 related items for PubMed ID: 11306609

  • 1. Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling.
    Gasparini L, Gouras GK, Wang R, Gross RS, Beal MF, Greengard P, Xu H.
    J Neurosci; 2001 Apr 15; 21(8):2561-70. PubMed ID: 11306609
    [Abstract] [Full Text] [Related]

  • 2. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
    Peng Y, Lee DY, Jiang L, Ma Z, Schachter SC, Lemere CA.
    Neuroscience; 2007 Dec 05; 150(2):386-95. PubMed ID: 17945434
    [Abstract] [Full Text] [Related]

  • 3. The secretion of amyloid beta-peptides is inhibited in the tacrine-treated human neuroblastoma cells.
    Lahiri DK, Farlow MR, Sambamurti K.
    Brain Res Mol Brain Res; 1998 Nov 20; 62(2):131-40. PubMed ID: 9813282
    [Abstract] [Full Text] [Related]

  • 4. Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons.
    Tong L, Balazs R, Thornton PL, Cotman CW.
    J Neurosci; 2004 Jul 28; 24(30):6799-809. PubMed ID: 15282285
    [Abstract] [Full Text] [Related]

  • 5. Control of amyloid-beta-peptide generation by subcellular trafficking of the beta-amyloid precursor protein and beta-secretase.
    Walter J.
    Neurodegener Dis; 2006 Jul 28; 3(4-5):247-54. PubMed ID: 17047364
    [Abstract] [Full Text] [Related]

  • 6. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology.
    Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM.
    FASEB J; 2005 Dec 28; 19(14):2081-2. PubMed ID: 16186174
    [Abstract] [Full Text] [Related]

  • 7. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.
    Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, Frosch MP, Eckman CB, Tanzi RE, Selkoe DJ, Guenette S.
    Proc Natl Acad Sci U S A; 2003 Apr 01; 100(7):4162-7. PubMed ID: 12634421
    [Abstract] [Full Text] [Related]

  • 8. Estrogen, beta-amyloid metabolism/trafficking, and Alzheimer's disease.
    Xu H, Wang R, Zhang YW, Zhang X.
    Ann N Y Acad Sci; 2006 Nov 01; 1089():324-42. PubMed ID: 17261779
    [Abstract] [Full Text] [Related]

  • 9. Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis.
    Greenfield JP, Leung LW, Cai D, Kaasik K, Gross RS, Rodriguez-Boulan E, Greengard P, Xu H.
    J Biol Chem; 2002 Apr 05; 277(14):12128-36. PubMed ID: 11823458
    [Abstract] [Full Text] [Related]

  • 10. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.
    Biochemistry; 1998 Nov 24; 37(47):16465-71. PubMed ID: 9843412
    [Abstract] [Full Text] [Related]

  • 11. O-GlcNAcylation of Amyloid-β Protein Precursor by Insulin Signaling Reduces Amyloid-β Production.
    Kwon OH, Cho YY, Kim TW, Chung S.
    J Alzheimers Dis; 2019 Nov 24; 69(4):1195-1211. PubMed ID: 31156159
    [Abstract] [Full Text] [Related]

  • 12. Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.
    Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB, Crews L, Moessler H, Masliah E.
    J Neurosci Res; 2006 May 15; 83(7):1252-61. PubMed ID: 16511867
    [Abstract] [Full Text] [Related]

  • 13. Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme.
    Vekrellis K, Ye Z, Qiu WQ, Walsh D, Hartley D, Chesneau V, Rosner MR, Selkoe DJ.
    J Neurosci; 2000 Mar 01; 20(5):1657-65. PubMed ID: 10684867
    [Abstract] [Full Text] [Related]

  • 14. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.
    Ho L, Qin W, Pompl PN, Xiang Z, Wang J, Zhao Z, Peng Y, Cambareri G, Rocher A, Mobbs CV, Hof PR, Pasinetti GM.
    FASEB J; 2004 May 01; 18(7):902-4. PubMed ID: 15033922
    [Abstract] [Full Text] [Related]

  • 15. The p38 mitogen-activated protein kinase signaling pathway is involved in regulating low-density lipoprotein receptor-related protein 1-mediated β-amyloid protein internalization in mouse brain.
    Ma KG, Lv J, Hu XD, Shi LL, Chang KW, Chen XL, Qian YH, Yang WN, Qu QM.
    Int J Biochem Cell Biol; 2016 Jul 01; 76():75-86. PubMed ID: 27163530
    [Abstract] [Full Text] [Related]

  • 16. Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons.
    Yang GZ, Yang M, Lim Y, Lu JJ, Wang TH, Qi JG, Zhong JH, Zhou XF.
    J Neurochem; 2012 Sep 01; 122(5):1010-22. PubMed ID: 22731248
    [Abstract] [Full Text] [Related]

  • 17. The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein.
    Petanceska SS, Gandy S.
    J Neurochem; 1999 Dec 01; 73(6):2316-20. PubMed ID: 10582589
    [Abstract] [Full Text] [Related]

  • 18. Presenilin-1 mutations associated with familial Alzheimer's disease do not disrupt protein transport from the endoplasmic reticulum to the Golgi apparatus.
    Tan Y, Hong J, Doan T, McConlogue L, Maltese WA.
    Biochim Biophys Acta; 1998 Jul 01; 1407(1):69-78. PubMed ID: 9639678
    [Abstract] [Full Text] [Related]

  • 19. Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer beta-amyloid peptides.
    Greenfield JP, Tsai J, Gouras GK, Hai B, Thinakaran G, Checler F, Sisodia SS, Greengard P, Xu H.
    Proc Natl Acad Sci U S A; 1999 Jan 19; 96(2):742-7. PubMed ID: 9892704
    [Abstract] [Full Text] [Related]

  • 20. O-GlcNAcylation promotes non-amyloidogenic processing of amyloid-β protein precursor via inhibition of endocytosis from the plasma membrane.
    Chun YS, Park Y, Oh HG, Kim TW, Yang HO, Park MK, Chung S.
    J Alzheimers Dis; 2015 Jan 19; 44(1):261-75. PubMed ID: 25208619
    [Abstract] [Full Text] [Related]

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