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176 related items for PubMed ID: 11306693

  • 1. Disparate role of Na(+) channel D2-S6 residues in batrachotoxin and local anesthetic action.
    Wang SY, Barile M, Wang GK.
    Mol Pharmacol; 2001 May; 59(5):1100-7. PubMed ID: 11306693
    [Abstract] [Full Text] [Related]

  • 2. Residues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities.
    Wang SY, Nau C, Wang GK.
    Biophys J; 2000 Sep; 79(3):1379-87. PubMed ID: 10969000
    [Abstract] [Full Text] [Related]

  • 3. Batrachotoxin-resistant Na+ channels derived from point mutations in transmembrane segment D4-S6.
    Wang SY, Wang GK.
    Biophys J; 1999 Jun; 76(6):3141-9. PubMed ID: 10354438
    [Abstract] [Full Text] [Related]

  • 4. A phenylalanine residue at segment D3-S6 in Nav1.4 voltage-gated Na(+) channels is critical for pyrethroid action.
    Wang SY, Barile M, Wang GK.
    Mol Pharmacol; 2001 Sep; 60(3):620-8. PubMed ID: 11502895
    [Abstract] [Full Text] [Related]

  • 5. Point mutations at N434 in D1-S6 of mu1 Na(+) channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers.
    Nau C, Wang SY, Strichartz GR, Wang GK.
    Mol Pharmacol; 1999 Aug; 56(2):404-13. PubMed ID: 10419561
    [Abstract] [Full Text] [Related]

  • 6. Serine-401 as a batrachotoxin- and local anesthetic-sensing residue in the human cardiac Na+ channel.
    Wang SY, Tikhonov DB, Zhorov BS, Mitchell J, Wang GK.
    Pflugers Arch; 2007 May; 454(2):277-87. PubMed ID: 17205354
    [Abstract] [Full Text] [Related]

  • 7. Local anesthetic block of batrachotoxin-resistant muscle Na+ channels.
    Wang GK, Quan C, Wang SY.
    Mol Pharmacol; 1998 Aug; 54(2):389-96. PubMed ID: 9687581
    [Abstract] [Full Text] [Related]

  • 8. Point mutations in segment I-S6 render voltage-gated Na+ channels resistant to batrachotoxin.
    Wang SY, Wang GK.
    Proc Natl Acad Sci U S A; 1998 Mar 03; 95(5):2653-8. PubMed ID: 9482942
    [Abstract] [Full Text] [Related]

  • 9. How batrachotoxin modifies the sodium channel permeation pathway: computer modeling and site-directed mutagenesis.
    Wang SY, Mitchell J, Tikhonov DB, Zhorov BS, Wang GK.
    Mol Pharmacol; 2006 Mar 03; 69(3):788-95. PubMed ID: 16354762
    [Abstract] [Full Text] [Related]

  • 10. Point mutations at L1280 in Nav1.4 channel D3-S6 modulate binding affinity and stereoselectivity of bupivacaine enantiomers.
    Nau C, Wang SY, Wang GK.
    Mol Pharmacol; 2003 Jun 03; 63(6):1398-406. PubMed ID: 12761351
    [Abstract] [Full Text] [Related]

  • 11. Altered stereoselectivity of cocaine and bupivacaine isomers in normal and batrachotoxin-modified Na+ channels.
    Wang GK, Wang SY.
    J Gen Physiol; 1992 Dec 03; 100(6):1003-20. PubMed ID: 1336539
    [Abstract] [Full Text] [Related]

  • 12. Single rat muscle Na+ channel mutation confers batrachotoxin autoresistance found in poison-dart frog Phyllobates terribilis.
    Wang SY, Wang GK.
    Proc Natl Acad Sci U S A; 2017 Sep 26; 114(39):10491-10496. PubMed ID: 28874544
    [Abstract] [Full Text] [Related]

  • 13. Modification of wild-type and batrachotoxin-resistant muscle mu1 Na+ channels by veratridine.
    Wang GK, Quan C, Seaver M, Wang SY.
    Pflugers Arch; 2000 Apr 26; 439(6):705-13. PubMed ID: 10784344
    [Abstract] [Full Text] [Related]

  • 14. Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics.
    Wright SN, Wang SY, Wang GK.
    Mol Pharmacol; 1998 Oct 26; 54(4):733-9. PubMed ID: 9765517
    [Abstract] [Full Text] [Related]

  • 15. Interactions of local anesthetics with voltage-gated Na+ channels.
    Nau C, Wang GK.
    J Membr Biol; 2004 Sep 01; 201(1):1-8. PubMed ID: 15635807
    [Abstract] [Full Text] [Related]

  • 16. Irreversible block of cardiac mutant Na+ channels by batrachotoxin.
    Wang SY, Tikhonov DB, Mitchell J, Zhorov BS, Wang GK.
    Channels (Austin); 2007 Sep 01; 1(3):179-88. PubMed ID: 18690024
    [Abstract] [Full Text] [Related]

  • 17. Time-dependent block and resurgent tail currents induced by mouse beta4(154-167) peptide in cardiac Na+ channels.
    Wang GK, Edrich T, Wang SY.
    J Gen Physiol; 2006 Mar 01; 127(3):277-89. PubMed ID: 16505148
    [Abstract] [Full Text] [Related]

  • 18. Block of human heart hH1 sodium channels by the enantiomers of bupivacaine.
    Nau C, Wang SY, Strichartz GR, Wang GK.
    Anesthesiology; 2000 Oct 01; 93(4):1022-33. PubMed ID: 11020758
    [Abstract] [Full Text] [Related]

  • 19. State-dependent block of voltage-gated Na+ channels by amitriptyline via the local anesthetic receptor and its implication for neuropathic pain.
    Wang GK, Russell C, Wang SY.
    Pain; 2004 Jul 01; 110(1-2):166-74. PubMed ID: 15275764
    [Abstract] [Full Text] [Related]

  • 20. Point-mutations related to the loss of batrachotoxin binding abolish the grayanotoxin effect in Na(+) channel isoforms.
    Ishii H, Kinoshita E, Kimura T, Yakehiro M, Yamaoka K, Imoto K, Mori Y, Seyama I.
    Jpn J Physiol; 1999 Oct 01; 49(5):457-61. PubMed ID: 10603430
    [Abstract] [Full Text] [Related]

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