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446 related items for PubMed ID: 11306706

  • 1. Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha.
    Hur E, Chang KY, Lee E, Lee SK, Park H.
    Mol Pharmacol; 2001 May; 59(5):1216-24. PubMed ID: 11306706
    [Abstract] [Full Text] [Related]

  • 2. p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.
    Richard DE, Berra E, Gothié E, Roux D, Pouysségur J.
    J Biol Chem; 1999 Nov 12; 274(46):32631-7. PubMed ID: 10551817
    [Abstract] [Full Text] [Related]

  • 3. Two transactivation domains of hypoxia-inducible factor-1alpha regulated by the MEK-1/p42/p44 MAPK pathway.
    Lee E, Yim S, Lee SK, Park H.
    Mol Cells; 2002 Aug 31; 14(1):9-15. PubMed ID: 12243358
    [Abstract] [Full Text] [Related]

  • 4. Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway.
    Yoo YG, Oh SH, Park ES, Cho H, Lee N, Park H, Kim DK, Yu DY, Seong JK, Lee MO.
    J Biol Chem; 2003 Oct 03; 278(40):39076-84. PubMed ID: 12855680
    [Abstract] [Full Text] [Related]

  • 5. Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy.
    Hofer T, Desbaillets I, Höpfl G, Gassmann M, Wenger RH.
    FASEB J; 2001 Dec 03; 15(14):2715-7. PubMed ID: 11606485
    [Abstract] [Full Text] [Related]

  • 6. HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation.
    Berra E, Richard DE, Gothié E, Pouysségur J.
    FEBS Lett; 2001 Feb 23; 491(1-2):85-90. PubMed ID: 11226425
    [Abstract] [Full Text] [Related]

  • 7. The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha.
    Sodhi A, Montaner S, Patel V, Zohar M, Bais C, Mesri EA, Gutkind JS.
    Cancer Res; 2000 Sep 01; 60(17):4873-80. PubMed ID: 10987301
    [Abstract] [Full Text] [Related]

  • 8. Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells.
    Tacchini L, Dansi P, Matteucci E, Desiderio MA.
    Carcinogenesis; 2001 Sep 01; 22(9):1363-71. PubMed ID: 11532856
    [Abstract] [Full Text] [Related]

  • 9. Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite.
    Duyndam MC, Hulscher ST, van der Wall E, Pinedo HM, Boven E.
    J Biol Chem; 2003 Feb 28; 278(9):6885-95. PubMed ID: 12482858
    [Abstract] [Full Text] [Related]

  • 10. Crosstalk of hypoxia-mediated signaling pathways in upregulating plasminogen activator inhibitor-1 expression in keloid fibroblasts.
    Zhang Q, Wu Y, Chau CH, Ann DK, Bertolami CN, Le AD.
    J Cell Physiol; 2004 Apr 28; 199(1):89-97. PubMed ID: 14978738
    [Abstract] [Full Text] [Related]

  • 11. ERK activation upon hypoxia: involvement in HIF-1 activation.
    Minet E, Arnould T, Michel G, Roland I, Mottet D, Raes M, Remacle J, Michiels C.
    FEBS Lett; 2000 Feb 18; 468(1):53-8. PubMed ID: 10683440
    [Abstract] [Full Text] [Related]

  • 12. VEGF production by primary human renal proximal tubular cells: requirement of HIF-1, PI3-kinase and MAPKK-1 signaling.
    Hellwig-Bürgel T, Stiehl DP, Katschinski DM, Marxsen J, Kreft B, Jelkmann W.
    Cell Physiol Biochem; 2005 Feb 18; 15(1-4):99-108. PubMed ID: 15665520
    [Abstract] [Full Text] [Related]

  • 13. Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1alpha/aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol.
    Hur E, Kim HH, Choi SM, Kim JH, Yim S, Kwon HJ, Choi Y, Kim DK, Lee MO, Park H.
    Mol Pharmacol; 2002 Nov 18; 62(5):975-82. PubMed ID: 12391259
    [Abstract] [Full Text] [Related]

  • 14. Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway.
    Kallio PJ, Wilson WJ, O'Brien S, Makino Y, Poellinger L.
    J Biol Chem; 1999 Mar 05; 274(10):6519-25. PubMed ID: 10037745
    [Abstract] [Full Text] [Related]

  • 15. Signaling angiogenesis via p42/p44 MAP kinase and hypoxia.
    Berra E, Milanini J, Richard DE, Le Gall M, Viñals F, Gothié E, Roux D, Pagès G, Pouysségur J.
    Biochem Pharmacol; 2000 Oct 15; 60(8):1171-8. PubMed ID: 11007955
    [Abstract] [Full Text] [Related]

  • 16. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C, Moore JW, Robertson N, Harris AL.
    Cancer Res; 2001 Oct 01; 61(19):7349-55. PubMed ID: 11585776
    [Abstract] [Full Text] [Related]

  • 17. AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells.
    Lee M, Hwang JT, Lee HJ, Jung SN, Kang I, Chi SG, Kim SS, Ha J.
    J Biol Chem; 2003 Oct 10; 278(41):39653-61. PubMed ID: 12900407
    [Abstract] [Full Text] [Related]

  • 18. Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1alpha.
    Yoo YG, Yeo MG, Kim DK, Park H, Lee MO.
    J Biol Chem; 2004 Dec 17; 279(51):53365-73. PubMed ID: 15385570
    [Abstract] [Full Text] [Related]

  • 19. Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.
    Hudson CC, Liu M, Chiang GG, Otterness DM, Loomis DC, Kaper F, Giaccia AJ, Abraham RT.
    Mol Cell Biol; 2002 Oct 17; 22(20):7004-14. PubMed ID: 12242281
    [Abstract] [Full Text] [Related]

  • 20. In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.
    Shi YH, Wang YX, Bingle L, Gong LH, Heng WJ, Li Y, Fang WG.
    J Pathol; 2005 Mar 17; 205(4):530-6. PubMed ID: 15714461
    [Abstract] [Full Text] [Related]

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