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Journal Abstract Search


269 related items for PubMed ID: 11309480

  • 1. The binding conformation of Taxol in beta-tubulin: a model based on electron crystallographic density.
    Snyder JP, Nettles JH, Cornett B, Downing KH, Nogales E.
    Proc Natl Acad Sci U S A; 2001 Apr 24; 98(9):5312-6. PubMed ID: 11309480
    [Abstract] [Full Text] [Related]

  • 2. The tubulin-bound conformation of paclitaxel: T-taxol vs "PTX-NY".
    Yang Y, Alcaraz AA, Snyder JP.
    J Nat Prod; 2009 Mar 27; 72(3):422-9. PubMed ID: 19267457
    [Abstract] [Full Text] [Related]

  • 3. The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography.
    Nettles JH, Li H, Cornett B, Krahn JM, Snyder JP, Downing KH.
    Science; 2004 Aug 06; 305(5685):866-9. PubMed ID: 15297674
    [Abstract] [Full Text] [Related]

  • 4. T-Taxol and the electron crystallographic density in beta-tubulin.
    Johnson SA, Alcaraz AA, Snyder JP.
    Org Lett; 2005 Dec 08; 7(25):5549-52. PubMed ID: 16320988
    [Abstract] [Full Text] [Related]

  • 5. Characterization of the Taxol binding site on the microtubule. Identification of Arg(282) in beta-tubulin as the site of photoincorporation of a 7-benzophenone analogue of Taxol.
    Rao S, He L, Chakravarty S, Ojima I, Orr GA, Horwitz SB.
    J Biol Chem; 1999 Dec 31; 274(53):37990-4. PubMed ID: 10608867
    [Abstract] [Full Text] [Related]

  • 6. The T-Taxol conformation.
    Alcaraz AA, Mehta AK, Johnson SA, Snyder JP.
    J Med Chem; 2006 Apr 20; 49(8):2478-88. PubMed ID: 16610791
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of a photoaffinity taxol analogue and its use in labeling tubulin.
    Dasgupta D, Park H, Harriman GC, Georg GI, Himes RH.
    J Med Chem; 1994 Sep 02; 37(18):2976-80. PubMed ID: 7915327
    [Abstract] [Full Text] [Related]

  • 8. Structure of tubulin at 6.5 A and location of the taxol-binding site.
    Nogales E, Wolf SG, Khan IA, Ludueña RF, Downing KH.
    Nature; 1995 Jun 01; 375(6530):424-7. PubMed ID: 7760939
    [Abstract] [Full Text] [Related]

  • 9. Structure-activity relationships of Taxol and Taxotere analogues.
    Guénard D, Guéritte-Voegelein F, Dubois J, Potier P.
    J Natl Cancer Inst Monogr; 1993 Jun 01; (15):79-82. PubMed ID: 7912533
    [Abstract] [Full Text] [Related]

  • 10. Structure-activity relationship of taxol inferring from docking taxol analogues to microtubule binding site.
    Xiang F, Yu J, Yin R, Ma Y, Yu L.
    Z Naturforsch C J Biosci; 2009 Jun 01; 64(7-8):551-6. PubMed ID: 19791508
    [Abstract] [Full Text] [Related]

  • 11. Use of the tubulin bound paclitaxel conformation for structure-based rational drug design.
    Geney R, Sun L, Pera P, Bernacki RJ, Xia S, Horwitz SB, Simmerling CL, Ojima I.
    Chem Biol; 2005 Mar 01; 12(3):339-48. PubMed ID: 15797218
    [Abstract] [Full Text] [Related]

  • 12. A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin.
    Xia S, Kenesky CS, Rucker PV, Smith AB, Orr GA, Horwitz SB.
    Biochemistry; 2006 Oct 03; 45(39):11762-75. PubMed ID: 17002277
    [Abstract] [Full Text] [Related]

  • 13. Photoaffinity labeling approach to map the Taxol-binding site on the microtubule.
    Orr GA, Rao S, Swindell CS, Kingston DG, Horwitz SB.
    Methods Enzymol; 1998 Oct 03; 298():238-52. PubMed ID: 9751886
    [No Abstract] [Full Text] [Related]

  • 14. Diastereomers of dibromo-7-epi-10-deacetylcephalomannine: crowded and cytotoxic taxanes exhibit halogen bonds.
    Jiang Y, Alcaraz AA, Chen JM, Kobayashi H, Lu YJ, Snyder JP.
    J Med Chem; 2006 Mar 23; 49(6):1891-9. PubMed ID: 16539375
    [Abstract] [Full Text] [Related]

  • 15. Much anticipated--the bioactive conformation of epothilone and its binding to tubulin.
    Heinz DW, Schubert WD, Höfle G.
    Angew Chem Int Ed Engl; 2005 Feb 18; 44(9):1298-301. PubMed ID: 15714588
    [No Abstract] [Full Text] [Related]

  • 16. The taxol pharmacophore and the T-taxol bridging principle.
    Kingston DG, Bane S, Snyder JP.
    Cell Cycle; 2005 Feb 18; 4(2):279-89. PubMed ID: 15611640
    [Abstract] [Full Text] [Related]

  • 17. Characterization of the taxol binding site on the microtubule. 2-(m-Azidobenzoyl)taxol photolabels a peptide (amino acids 217-231) of beta-tubulin.
    Rao S, Orr GA, Chaudhary AG, Kingston DG, Horwitz SB.
    J Biol Chem; 1995 Sep 01; 270(35):20235-8. PubMed ID: 7657589
    [Abstract] [Full Text] [Related]

  • 18. Refined structure of alpha beta-tubulin at 3.5 A resolution.
    Löwe J, Li H, Downing KH, Nogales E.
    J Mol Biol; 2001 Nov 09; 313(5):1045-57. PubMed ID: 11700061
    [Abstract] [Full Text] [Related]

  • 19. Structure of the alpha beta tubulin dimer by electron crystallography.
    Nogales E, Wolf SG, Downing KH.
    Nature; 1998 Jan 08; 391(6663):199-203. PubMed ID: 9428769
    [Abstract] [Full Text] [Related]

  • 20. Synthesis, biological evaluations, and tubulin binding poses of C-2alpha sulfur linked taxol analogues.
    Wang L, Alcaraz AA, Matesanz R, Yang CG, Barasoain I, Díaz JF, Li YZ, Snyder JP, Fang WS.
    Bioorg Med Chem Lett; 2007 Jun 01; 17(11):3191-4. PubMed ID: 17395465
    [Abstract] [Full Text] [Related]


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