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203 related items for PubMed ID: 11318841

  • 1. Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53).
    Gloyn AL, Hashim Y, Ashcroft SJ, Ashfield R, Wiltshire S, Turner RC, UK Prospective Diabetes Study (UKPDS 53).
    Diabet Med; 2001 Mar; 18(3):206-12. PubMed ID: 11318841
    [Abstract] [Full Text] [Related]

  • 2. Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes.
    Gloyn AL, Weedon MN, Owen KR, Turner MJ, Knight BA, Hitman G, Walker M, Levy JC, Sampson M, Halford S, McCarthy MI, Hattersley AT, Frayling TM.
    Diabetes; 2003 Feb; 52(2):568-72. PubMed ID: 12540637
    [Abstract] [Full Text] [Related]

  • 3. Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region.
    Florez JC, Burtt N, de Bakker PI, Almgren P, Tuomi T, Holmkvist J, Gaudet D, Hudson TJ, Schaffner SF, Daly MJ, Hirschhorn JN, Groop L, Altshuler D.
    Diabetes; 2004 May; 53(5):1360-8. PubMed ID: 15111507
    [Abstract] [Full Text] [Related]

  • 4. Effective treatment with oral sulfonylureas in patients with diabetes due to sulfonylurea receptor 1 (SUR1) mutations.
    Rafiq M, Flanagan SE, Patch AM, Shields BM, Ellard S, Hattersley AT, Neonatal Diabetes International Collaborative Group.
    Diabetes Care; 2008 Feb; 31(2):204-9. PubMed ID: 18025408
    [Abstract] [Full Text] [Related]

  • 5. Common variants in the ATP-sensitive K+ channel genes KCNJ11 (Kir6.2) and ABCC8 (SUR1) in relation to glucose intolerance: population-based studies and meta-analyses.
    van Dam RM, Hoebee B, Seidell JC, Schaap MM, de Bruin TW, Feskens EJ.
    Diabet Med; 2005 May; 22(5):590-8. PubMed ID: 15842514
    [Abstract] [Full Text] [Related]

  • 6. Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro.
    Sakura H, Wat N, Horton V, Millns H, Turner RC, Ashcroft FM.
    Diabetologia; 1996 Oct; 39(10):1233-6. PubMed ID: 8897013
    [Abstract] [Full Text] [Related]

  • 7. Sulfonylurea receptor 1 gene variants are associated with gestational diabetes and type 2 diabetes but not with altered secretion of insulin.
    Rissanen J, Markkanen A, Kärkkäinen P, Pihlajamäki J, Kekäläinen P, Mykkänen L, Kuusisto J, Karhapää P, Niskanen L, Laakso M.
    Diabetes Care; 2000 Jan; 23(1):70-3. PubMed ID: 10857971
    [Abstract] [Full Text] [Related]

  • 8. Polymorphisms of the SUR1 (ABCC8) and Kir6.2 (KCNJ11) genes predict the conversion from impaired glucose tolerance to type 2 diabetes. The Finnish Diabetes Prevention Study.
    Laukkanen O, Pihlajamäki J, Lindström J, Eriksson J, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Uusitupa M, Laakso M, Finnish Diabetes Prevention Study Group.
    J Clin Endocrinol Metab; 2004 Dec; 89(12):6286-90. PubMed ID: 15579791
    [Abstract] [Full Text] [Related]

  • 9. Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene.
    Hansen T, Echwald SM, Hansen L, Møller AM, Almind K, Clausen JO, Urhammer SA, Inoue H, Ferrer J, Bryan J, Aguilar-Bryan L, Permutt MA, Pedersen O.
    Diabetes; 1998 Apr; 47(4):598-605. PubMed ID: 9568693
    [Abstract] [Full Text] [Related]

  • 10. Characterization of the mouse sulfonylurea receptor 1 promoter and its regulation.
    Hernández-Sánchez C, Ito Y, Ferrer J, Reitman M, LeRoith D.
    J Biol Chem; 1999 Jun 25; 274(26):18261-70. PubMed ID: 10373428
    [Abstract] [Full Text] [Related]

  • 11. Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM.
    Ohta Y, Tanizawa Y, Inoue H, Hosaka T, Ueda K, Matsutani A, Repunte VP, Yamada M, Kurachi Y, Bryan J, Aguilar-Bryan L, Permutt MA, Oka Y.
    Diabetes; 1998 Mar 25; 47(3):476-81. PubMed ID: 9519757
    [Abstract] [Full Text] [Related]

  • 12. Genetic variability of the SUR1 promoter in relation to beta-cell function and Type II diabetes mellitus.
    Hansen T, Ambye L, Grarup N, Hansen L, Echwald SM, Ferrer J, Pedersen O.
    Diabetologia; 2001 Oct 25; 44(10):1330-4. PubMed ID: 11692183
    [Abstract] [Full Text] [Related]

  • 13. Variants in the sulphonylurea receptor gene: association of the exon 16-3t variant with Type II diabetes mellitus in Dutch Caucasians.
    Hart LM, de Knijff P, Dekker JM, Stolk RP, Nijpels G, van der Does FE, Ruige JB, Grobbee DE, Heine RJ, Maassen JA.
    Diabetologia; 1999 May 25; 42(5):617-20. PubMed ID: 10333056
    [Abstract] [Full Text] [Related]

  • 14. Sequence variants in the pancreatic islet beta-cell inwardly rectifying K+ channel Kir6.2 (Bir) gene: identification and lack of role in Caucasian patients with NIDDM.
    Inoue H, Ferrer J, Warren-Perry M, Zhang Y, Millns H, Turner RC, Elbein SC, Hampe CL, Suarez BK, Inagaki N, Seino S, Permutt MA.
    Diabetes; 1997 Mar 25; 46(3):502-7. PubMed ID: 9032109
    [Abstract] [Full Text] [Related]

  • 15. Regulated expression of adenosine triphosphate-sensitive potassium channel subunits in pancreatic beta-cells.
    Moritz W, Leech CA, Ferrer J, Habener JF.
    Endocrinology; 2001 Jan 25; 142(1):129-38. PubMed ID: 11145575
    [Abstract] [Full Text] [Related]

  • 16. Coexpression of the type 2 diabetes susceptibility gene variants KCNJ11 E23K and ABCC8 S1369A alter the ATP and sulfonylurea sensitivities of the ATP-sensitive K(+) channel.
    Hamming KS, Soliman D, Matemisz LC, Niazi O, Lang Y, Gloyn AL, Light PE.
    Diabetes; 2009 Oct 25; 58(10):2419-24. PubMed ID: 19587354
    [Abstract] [Full Text] [Related]

  • 17. Sulfonylurea receptor -1 (SUR1): genetic and metabolic evidences for a role in the susceptibility to type 2 diabetes mellitus.
    Reis AF, Velho G.
    Diabetes Metab; 2002 Feb 25; 28(1):14-9. PubMed ID: 11938023
    [Abstract] [Full Text] [Related]

  • 18. Sulfonylurea receptor gene 16-3 polymorphism - association with sulfonylurea or insulin treatment in type 2 diabetic subjects.
    Zychma MJ, Gumprecht J, Strojek K, Grzeszczak W, Moczulski D, Trautsolt W, Karasek D.
    Med Sci Monit; 2002 Jul 25; 8(7):CR512-5. PubMed ID: 12118200
    [Abstract] [Full Text] [Related]

  • 19. Effects of single nucleotide polymorphisms in K(ATP) channel genes on type 2 diabetes in a Turkish population.
    Gonen MS, Arikoglu H, Erkoc Kaya D, Ozdemir H, Ipekci SH, Arslan A, Kayis SA, Gogebakan B.
    Arch Med Res; 2012 May 25; 43(4):317-23. PubMed ID: 22704848
    [Abstract] [Full Text] [Related]

  • 20. Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects.
    Yokoi N, Kanamori M, Horikawa Y, Takeda J, Sanke T, Furuta H, Nanjo K, Mori H, Kasuga M, Hara K, Kadowaki T, Tanizawa Y, Oka Y, Iwami Y, Ohgawara H, Yamada Y, Seino Y, Yano H, Cox NJ, Seino S.
    Diabetes; 2006 Aug 25; 55(8):2379-86. PubMed ID: 16873704
    [Abstract] [Full Text] [Related]

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