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Journal Abstract Search

186 related items for PubMed ID: 11323713

  • 1. Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis.
    Greasley SE, Horton P, Ramcharan J, Beardsley GP, Benkovic SJ, Wilson IA.
    Nat Struct Biol; 2001 May; 8(5):402-6. PubMed ID: 11323713
    [Abstract] [Full Text] [Related]

  • 2. Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor.
    Wolan DW, Cheong CG, Greasley SE, Wilson IA.
    Biochemistry; 2004 Feb 10; 43(5):1171-83. PubMed ID: 14756553
    [Abstract] [Full Text] [Related]

  • 3. Structural insights into the avian AICAR transformylase mechanism.
    Wolan DW, Greasley SE, Beardsley GP, Wilson IA.
    Biochemistry; 2002 Dec 31; 41(52):15505-13. PubMed ID: 12501179
    [Abstract] [Full Text] [Related]

  • 4. Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) from Staphylococcus lugdunensis.
    Verma P, Kar B, Varshney R, Roy P, Sharma AK.
    FEBS J; 2017 Dec 31; 284(24):4233-4261. PubMed ID: 29063699
    [Abstract] [Full Text] [Related]

  • 5. Catalytic mechanism of the cyclohydrolase activity of human aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase.
    Vergis JM, Beardsley GP.
    Biochemistry; 2004 Feb 10; 43(5):1184-92. PubMed ID: 14756554
    [Abstract] [Full Text] [Related]

  • 6. Structural analyses of a purine biosynthetic enzyme from Mycobacterium tuberculosis reveal a novel bound nucleotide.
    Le Nours J, Bulloch EM, Zhang Z, Greenwood DR, Middleditch MJ, Dickson JM, Baker EN.
    J Biol Chem; 2011 Nov 25; 286(47):40706-16. PubMed ID: 21956117
    [Abstract] [Full Text] [Related]

  • 7. Human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase. A bifunctional protein requiring dimerization for transformylase activity but not for cyclohydrolase activity.
    Vergis JM, Bulock KG, Fleming KG, Beardsley GP.
    J Biol Chem; 2001 Mar 16; 276(11):7727-33. PubMed ID: 11096114
    [Abstract] [Full Text] [Related]

  • 8. Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site.
    Wolan DW, Greasley SE, Wall MJ, Benkovic SJ, Wilson IA.
    Biochemistry; 2003 Sep 23; 42(37):10904-14. PubMed ID: 12974624
    [Abstract] [Full Text] [Related]

  • 9. Analysis of substrate binding in individual active sites of bifunctional human ATIC.
    Witkowska D, Cox HL, Hall TC, Wildsmith GC, Machin DC, Webb ME.
    Biochim Biophys Acta Proteins Proteom; 2018 Feb 23; 1866(2):254-263. PubMed ID: 29042184
    [Abstract] [Full Text] [Related]

  • 10. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates.
    Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA.
    J Biol Chem; 2004 Apr 23; 279(17):18034-45. PubMed ID: 14966129
    [Abstract] [Full Text] [Related]

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  • 12. Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) bifunctional enzyme from Candidatus Liberibacer asiaticus.
    Lonare S, Rode S, Verma P, Verma S, Kaur H, Alam MS, Wangmo P, Kumar P, Roy P, Sharma AK.
    Biochim Biophys Acta Proteins Proteom; 2024 Jul 01; 1872(4):141015. PubMed ID: 38615986
    [Abstract] [Full Text] [Related]

  • 13. A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase.
    Kang YN, Tran A, White RH, Ealick SE.
    Biochemistry; 2007 May 01; 46(17):5050-62. PubMed ID: 17407260
    [Abstract] [Full Text] [Related]

  • 14. Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution.
    Axelrod HL, McMullan D, Krishna SS, Miller MD, Elsliger MA, Abdubek P, Ambing E, Astakhova T, Carlton D, Chiu HJ, Clayton T, Duan L, Feuerhelm J, Grzechnik SK, Hale J, Han GW, Haugen J, Jaroszewski L, Jin KK, Klock HE, Knuth MW, Koesema E, Morse AT, Nigoghossian E, Okach L, Oommachen S, Paulsen J, Quijano K, Reyes R, Rife CL, van den Bedem H, Weekes D, White A, Wolf G, Xu Q, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA.
    Proteins; 2008 May 01; 71(2):1042-9. PubMed ID: 18260100
    [No Abstract] [Full Text] [Related]

  • 15. Crystallization and preliminary crystallographic investigations of avian 5-aminoimidazole-4-carboxamide ribonucleotide transformylase-inosine monophosphate cyclohydrolase expressed in Escherichia coli.
    Reyes VM, Greasley SE, Stura EA, Beardsley GP, Wilson IA.
    Acta Crystallogr D Biol Crystallogr; 2000 Aug 01; 56(Pt 8):1051-4. PubMed ID: 10944351
    [Abstract] [Full Text] [Related]

  • 16. X-ray crystal structure of glycinamide ribonucleotide synthetase from Escherichia coli.
    Wang W, Kappock TJ, Stubbe J, Ealick SE.
    Biochemistry; 1998 Nov 10; 37(45):15647-62. PubMed ID: 9843369
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  • 19. Radioassay of bifunctional 5-aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase by thin-layer chromatography.
    Szabados E, Christopherson RI.
    Anal Biochem; 1994 Sep 10; 221(2):401-4. PubMed ID: 7810885
    [Abstract] [Full Text] [Related]

  • 20. Virtual screening of human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase against the NCI diversity set by use of AutoDock to identify novel nonfolate inhibitors.
    Li C, Xu L, Wolan DW, Wilson IA, Olson AJ.
    J Med Chem; 2004 Dec 30; 47(27):6681-90. PubMed ID: 15615517
    [Abstract] [Full Text] [Related]

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