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Journal Abstract Search


270 related items for PubMed ID: 11325826

  • 1. Active Ras induces heterodimerization of cRaf and BRaf.
    Weber CK, Slupsky JR, Kalmes HA, Rapp UR.
    Cancer Res; 2001 May 01; 61(9):3595-8. PubMed ID: 11325826
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers.
    Peng SB, Henry JR, Kaufman MD, Lu WP, Smith BD, Vogeti S, Rutkoski TJ, Wise S, Chun L, Zhang Y, Van Horn RD, Yin T, Zhang X, Yadav V, Chen SH, Gong X, Ma X, Webster Y, Buchanan S, Mochalkin I, Huber L, Kays L, Donoho GP, Walgren J, McCann D, Patel P, Conti I, Plowman GD, Starling JJ, Flynn DL.
    Cancer Cell; 2015 Sep 14; 28(3):384-98. PubMed ID: 26343583
    [Abstract] [Full Text] [Related]

  • 3. Ras mediates radioresistance through both phosphatidylinositol 3-kinase-dependent and Raf-dependent but mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-independent signaling pathways.
    Grana TM, Rusyn EV, Zhou H, Sartor CI, Cox AD.
    Cancer Res; 2002 Jul 15; 62(14):4142-50. PubMed ID: 12124353
    [Abstract] [Full Text] [Related]

  • 4. Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization.
    Garnett MJ, Rana S, Paterson H, Barford D, Marais R.
    Mol Cell; 2005 Dec 22; 20(6):963-9. PubMed ID: 16364920
    [Abstract] [Full Text] [Related]

  • 5. The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking phospho-Ser-621 in the C terminus of CRAF.
    Yuan J, Ng WH, Yap J, Chia B, Huang X, Wang M, Hu J.
    J Biol Chem; 2018 Sep 14; 293(37):14276-14284. PubMed ID: 30030377
    [Abstract] [Full Text] [Related]

  • 6. In vitro inhibition of Ras-Raf association by short peptides.
    Barnard D, Sun H, Baker L, Marshall MS.
    Biochem Biophys Res Commun; 1998 Jun 09; 247(1):176-80. PubMed ID: 9636675
    [Abstract] [Full Text] [Related]

  • 7. Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1.
    Sasaki A, Taketomi T, Kato R, Saeki K, Nonami A, Sasaki M, Kuriyama M, Saito N, Shibuya M, Yoshimura A.
    Nat Cell Biol; 2003 May 09; 5(5):427-32. PubMed ID: 12717443
    [Abstract] [Full Text] [Related]

  • 8. Raf and RhoA cooperate to transform intestinal epithelial cells and induce growth resistance to transforming growth factor beta.
    Du J, Jiang B, Coffey RJ, Barnard J.
    Mol Cancer Res; 2004 Apr 09; 2(4):233-41. PubMed ID: 15140945
    [Abstract] [Full Text] [Related]

  • 9. Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors.
    Chatelle CV, Hövermann D, Müller A, Wagner HJ, Weber W, Radziwill G.
    Sci Rep; 2016 Mar 30; 6():23713. PubMed ID: 27025703
    [Abstract] [Full Text] [Related]

  • 10. Modulation of phospholipase D by Ras proteins mediated by its effectors Ral-GDS, PI3K and Raf-1.
    Lucas L, Penalva V, Ramírez de Molina A, Del Peso L, Lacal JC.
    Int J Oncol; 2002 Sep 30; 21(3):477-85. PubMed ID: 12168089
    [Abstract] [Full Text] [Related]

  • 11. Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.
    Heidorn SJ, Milagre C, Whittaker S, Nourry A, Niculescu-Duvas I, Dhomen N, Hussain J, Reis-Filho JS, Springer CJ, Pritchard C, Marais R.
    Cell; 2010 Jan 22; 140(2):209-21. PubMed ID: 20141835
    [Abstract] [Full Text] [Related]

  • 12. ARAF acts as a scaffold to stabilize BRAF:CRAF heterodimers.
    Rebocho AP, Marais R.
    Oncogene; 2013 Jun 27; 32(26):3207-12. PubMed ID: 22926515
    [Abstract] [Full Text] [Related]

  • 13. Raf inhibitors target ras spatiotemporal dynamics.
    Cho KJ, Kasai RS, Park JH, Chigurupati S, Heidorn SJ, van der Hoeven D, Plowman SJ, Kusumi A, Marais R, Hancock JF.
    Curr Biol; 2012 Jun 05; 22(11):945-55. PubMed ID: 22560614
    [Abstract] [Full Text] [Related]

  • 14. Flagellin and lipopolysaccharide stimulate the MEK-ERK signaling pathway in chicken heterophils through differential activation of the small GTPases, Ras and Rap1.
    Kogut MH, Genovese KJ, He H.
    Mol Immunol; 2007 Mar 05; 44(7):1729-36. PubMed ID: 17045653
    [Abstract] [Full Text] [Related]

  • 15. Opposite role of Ras in tumor necrosis factor-alpha-induced cell cycle regulation: competition for Raf kinase.
    Park SJ, Kim YY, Lim JY, Seo GJ, Kim J, Park SI, Park BJ.
    Biochem Biophys Res Commun; 2001 Oct 12; 287(5):1140-7. PubMed ID: 11587542
    [Abstract] [Full Text] [Related]

  • 16. Analyses of the oncogenic BRAFD594G variant reveal a kinase-independent function of BRAF in activating MAPK signaling.
    Cope NJ, Novak B, Liu Z, Cavallo M, Gunderwala AY, Connolly M, Wang Z.
    J Biol Chem; 2020 Feb 21; 295(8):2407-2420. PubMed ID: 31929109
    [Abstract] [Full Text] [Related]

  • 17. Three distinct regions of cRaf kinase domain interact with membrane.
    Prakash P, Hancock JF, Gorfe AA.
    Sci Rep; 2019 Feb 14; 9(1):2057. PubMed ID: 30765804
    [Abstract] [Full Text] [Related]

  • 18. Calmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signaling.
    Villalonga P, López-Alcalá C, Bosch M, Chiloeches A, Rocamora N, Gil J, Marais R, Marshall CJ, Bachs O, Agell N.
    Mol Cell Biol; 2001 Nov 14; 21(21):7345-54. PubMed ID: 11585916
    [Abstract] [Full Text] [Related]

  • 19. Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF.
    Hu J, Yu H, Kornev AP, Zhao J, Filbert EL, Taylor SS, Shaw AS.
    Proc Natl Acad Sci U S A; 2011 Apr 12; 108(15):6067-72. PubMed ID: 21441104
    [Abstract] [Full Text] [Related]

  • 20. Registered report: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.
    Bhargava A, Anant M, Mack H, Reproducibility Project: Cancer Biology, Reproducibility Project Cancer Biology.
    Elife; 2016 Feb 17; 5():. PubMed ID: 26885666
    [Abstract] [Full Text] [Related]


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