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Journal Abstract Search

178 related items for PubMed ID: 11327849

  • 1. Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam.
    Kuzin AP, Nukaga M, Nukaga Y, Hujer A, Bonomo RA, Knox JR.
    Biochemistry; 2001 Feb 13; 40(6):1861-6. PubMed ID: 11327849
    [Abstract] [Full Text] [Related]

  • 2. Inhibitor-resistant class A beta-lactamases: consequences of the Ser130-to-Gly mutation seen in Apo and tazobactam structures of the SHV-1 variant.
    Sun T, Bethel CR, Bonomo RA, Knox JR.
    Biochemistry; 2004 Nov 09; 43(44):14111-7. PubMed ID: 15518561
    [Abstract] [Full Text] [Related]

  • 3. Rational design of a beta-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 A crystal structure of wt SHV-1 complex with a penam sulfone.
    Padayatti PS, Sheri A, Totir MA, Helfand MS, Carey MP, Anderson VE, Carey PR, Bethel CR, Bonomo RA, Buynak JD, van den Akker F.
    J Am Chem Soc; 2006 Oct 11; 128(40):13235-42. PubMed ID: 17017804
    [Abstract] [Full Text] [Related]

  • 4. Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors.
    Helfand MS, Taracila MA, Totir MA, Bonomo RA, Buynak JD, van den Akker F, Carey PR.
    Biochemistry; 2007 Jul 24; 46(29):8689-99. PubMed ID: 17595114
    [Abstract] [Full Text] [Related]

  • 5. Different intermediate populations formed by tazobactam, sulbactam, and clavulanate reacting with SHV-1 beta-lactamases: Raman crystallographic evidence.
    Kalp M, Totir MA, Buynak JD, Carey PR.
    J Am Chem Soc; 2009 Feb 18; 131(6):2338-47. PubMed ID: 19161282
    [Abstract] [Full Text] [Related]

  • 6. High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase.
    Padayatti PS, Helfand MS, Totir MA, Carey MP, Carey PR, Bonomo RA, van den Akker F.
    J Biol Chem; 2005 Oct 14; 280(41):34900-7. PubMed ID: 16055923
    [Abstract] [Full Text] [Related]

  • 7. Penam sulfones and β-lactamase inhibition: SA2-13 and the importance of the C2 side chain length and composition.
    Rodkey EA, Winkler ML, Bethel CR, Pagadala SR, Buynak JD, Bonomo RA, van den Akker F.
    PLoS One; 2014 Oct 14; 9(1):e85892. PubMed ID: 24454944
    [Abstract] [Full Text] [Related]

  • 8. Effect of the inhibitor-resistant M69V substitution on the structures and populations of trans-enamine beta-lactamase intermediates.
    Totir MA, Padayatti PS, Helfand MS, Carey MP, Bonomo RA, Carey PR, van den Akker F.
    Biochemistry; 2006 Oct 03; 45(39):11895-904. PubMed ID: 17002290
    [Abstract] [Full Text] [Related]

  • 9. Tazobactam forms a stoichiometric trans-enamine intermediate in the E166A variant of SHV-1 beta-lactamase: 1.63 A crystal structure.
    Padayatti PS, Helfand MS, Totir MA, Carey MP, Hujer AM, Carey PR, Bonomo RA, van den Akker F.
    Biochemistry; 2004 Feb 03; 43(4):843-8. PubMed ID: 14744126
    [Abstract] [Full Text] [Related]

  • 10. Studies on penam sulfones. I. Synthesis and beta-lactamase inhibitory activity of 2 beta-alkoxycarbonyl penicillanic acid sulfones.
    Setti EL, Reddy NA, Phillips OA, Czajkowski DP, Atchison K, Atwal H, Micetich RG, Maiti SN, Kunugita C, Hyodo A.
    J Antibiot (Tokyo); 1996 Sep 03; 49(9):944-6. PubMed ID: 8931732
    [No Abstract] [Full Text] [Related]

  • 11. Crystal structures of the molecular class A β-lactamase TEM-171 and its complexes with tazobactam.
    Grigorenko VG, Petrova TE, Carolan C, Rubtsova MY, Uporov IV, Pereira J, Chojnowski G, Samygina VR, Lamzin VS, Egorov AM.
    Acta Crystallogr D Struct Biol; 2022 Jul 01; 78(Pt 7):825-834. PubMed ID: 35775982
    [Abstract] [Full Text] [Related]

  • 12. Tazobactam inactivation of SHV-1 and the inhibitor-resistant Ser130 -->Gly SHV-1 beta-lactamase: insights into the mechanism of inhibition.
    Pagan-Rodriguez D, Zhou X, Simmons R, Bethel CR, Hujer AM, Helfand MS, Jin Z, Guo B, Anderson VE, Ng LM, Bonomo RA.
    J Biol Chem; 2004 May 07; 279(19):19494-501. PubMed ID: 14757767
    [Abstract] [Full Text] [Related]

  • 13. Evaluation of inhibition of the carbenicillin-hydrolyzing beta-lactamase PSE-4 by the clinically used mechanism-based inhibitors.
    Therrien C, Kotra LP, Sanschagrin F, Mobashery S, Levesque RC.
    FEBS Lett; 2000 Mar 31; 470(3):285-92. PubMed ID: 10745083
    [Abstract] [Full Text] [Related]

  • 14. Sulbactam forms only minimal amounts of irreversible acrylate-enzyme with SHV-1 beta-lactamase.
    Totir MA, Helfand MS, Carey MP, Sheri A, Buynak JD, Bonomo RA, Carey PR.
    Biochemistry; 2007 Aug 07; 46(31):8980-7. PubMed ID: 17630699
    [Abstract] [Full Text] [Related]

  • 15. Crystal structures of KPC-2 β-lactamase in complex with 3-nitrophenyl boronic acid and the penam sulfone PSR-3-226.
    Ke W, Bethel CR, Papp-Wallace KM, Pagadala SR, Nottingham M, Fernandez D, Buynak JD, Bonomo RA, van den Akker F.
    Antimicrob Agents Chemother; 2012 May 07; 56(5):2713-8. PubMed ID: 22330909
    [Abstract] [Full Text] [Related]

  • 16. Novel insights into the mode of inhibition of class A SHV-1 beta-lactamases revealed by boronic acid transition state inhibitors.
    Ke W, Sampson JM, Ori C, Prati F, Drawz SM, Bethel CR, Bonomo RA, van den Akker F.
    Antimicrob Agents Chemother; 2011 Jan 07; 55(1):174-83. PubMed ID: 21041505
    [Abstract] [Full Text] [Related]

  • 17. Why tazobactam and sulbactam have different intermediates population with SHV-1 β-lactamase: a molecular dynamics study.
    Li R, Wang YT, Chen CL.
    J Mol Model; 2013 Jun 07; 19(6):2519-24. PubMed ID: 23455927
    [Abstract] [Full Text] [Related]

  • 18. Comparative activities of clavulanic acid, sulbactam, and tazobactam against clinically important beta-lactamases.
    Payne DJ, Cramp R, Winstanley DJ, Knowles DJ.
    Antimicrob Agents Chemother; 1994 Apr 07; 38(4):767-72. PubMed ID: 8031044
    [Abstract] [Full Text] [Related]

  • 19. Characterization of a PSE-4 mutant with different properties in relation to penicillanic acid sulfones: importance of residues 216 to 218 in class A beta-lactamases.
    Sabbagh Y, Thériault E, Sanschagrin F, Voyer N, Palzkill T, Levesque RC.
    Antimicrob Agents Chemother; 1998 Sep 07; 42(9):2319-25. PubMed ID: 9736556
    [Abstract] [Full Text] [Related]

  • 20. Following the reactions of mechanism-based inhibitors with beta-lactamase by Raman crystallography.
    Helfand MS, Totir MA, Carey MP, Hujer AM, Bonomo RA, Carey PR.
    Biochemistry; 2003 Nov 25; 42(46):13386-92. PubMed ID: 14621983
    [Abstract] [Full Text] [Related]

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