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465 related items for PubMed ID: 11336554

  • 1. Evolution of AZT resistance in HIV-1: the 41-70 intermediate that is not observed in vivo has a replication defect.
    Jeeninga RE, Keulen W, Boucher C, Sanders RW, Berkhout B.
    Virology; 2001 May 10; 283(2):294-305. PubMed ID: 11336554
    [Abstract] [Full Text] [Related]

  • 2. Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.
    Boyer PL, Imamichi T, Sarafianos SG, Arnold E, Hughes SH.
    J Virol; 2004 Sep 10; 78(18):9987-97. PubMed ID: 15331732
    [Abstract] [Full Text] [Related]

  • 3. Prevalence of primary resistance to zidovudine and lamivudine in drug-naive human immunodeficiency virus type-1 infected patients: high proportion of reverse transcriptase codon 215 mutant in circulating lymphocytes and free virus.
    Trabaud MA, Leriche-Guerin K, Regis C, Bordes I, Cotte L, Detmer J, Kolberg J, Ritter J, Trépo C.
    J Med Virol; 2000 Jul 10; 61(3):352-9. PubMed ID: 10861645
    [Abstract] [Full Text] [Related]

  • 4. Identification of insertion mutations in HIV-1 reverse transcriptase causing multiple drug resistance to nucleoside analogue reverse transcriptase inhibitors.
    Sugiura W, Matsuda M, Matsuda Z, Abumi H, Okano A, Oishi T, Moriya K, Yamamoto Y, Fukutake K, Mimaya J, Ajisawa A, Taki M, Yamada K, Nagai Y.
    J Hum Virol; 1999 Jul 10; 2(3):146-53. PubMed ID: 10413366
    [Abstract] [Full Text] [Related]

  • 5. Transmitted human immunodeficiency virus type 1 carrying the D67N or K219Q/E mutation evolves rapidly to zidovudine resistance in vitro and shows a high replicative fitness in the presence of zidovudine.
    García-Lerma JG, MacInnes H, Bennett D, Weinstock H, Heneine W.
    J Virol; 2004 Jul 10; 78(14):7545-52. PubMed ID: 15220429
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  • 7. In vitro characterization of a simian immunodeficiency virus-human immunodeficiency virus (HIV) chimera expressing HIV type 1 reverse transcriptase to study antiviral resistance in pigtail macaques.
    Ambrose Z, Boltz V, Palmer S, Coffin JM, Hughes SH, Kewalramani VN.
    J Virol; 2004 Dec 10; 78(24):13553-61. PubMed ID: 15564466
    [Abstract] [Full Text] [Related]

  • 8. Novel nonnucleoside inhibitors that select nucleoside inhibitor resistance mutations in human immunodeficiency virus type 1 reverse transcriptase.
    Zhang Z, Walker M, Xu W, Shim JH, Girardet JL, Hamatake RK, Hong Z.
    Antimicrob Agents Chemother; 2006 Aug 10; 50(8):2772-81. PubMed ID: 16870771
    [Abstract] [Full Text] [Related]

  • 9. Augmentation of human immunodeficiency virus type 1 subtype E (CRF01_AE) multiple-drug resistance by insertion of a foreign 11-amino-acid fragment into the reverse transcriptase.
    Sato H, Tomita Y, Ebisawa K, Hachiya A, Shibamura K, Shiino T, Yang R, Tatsumi M, Gushi K, Umeyama H, Oka S, Takebe Y, Nagai Y.
    J Virol; 2001 Jun 10; 75(12):5604-13. PubMed ID: 11356968
    [Abstract] [Full Text] [Related]

  • 10. Mechanistic basis of zidovudine hypersusceptibility and lamivudine resistance conferred by the deletion of codon 69 in the HIV-1 reverse transcriptase coding region.
    Kisic M, Mendieta J, Puertas MC, Parera M, Martínez MA, Martinez-Picado J, Menéndez-Arias L.
    J Mol Biol; 2008 Oct 03; 382(2):327-41. PubMed ID: 18662701
    [Abstract] [Full Text] [Related]

  • 11. Use of evolutionary limitations of HIV-1 multidrug resistance to optimize therapy.
    Chow YK, Hirsch MS, Merrill DP, Bechtel LJ, Eron JJ, Kaplan JC, D'Aquila RT.
    Nature; 1993 Feb 18; 361(6413):650-4. PubMed ID: 7679778
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  • 13. Single-step kinetics of HIV-1 reverse transcriptase mutants responsible for virus resistance to nucleoside inhibitors zidovudine and 3-TC.
    Krebs R, Immendörfer U, Thrall SH, Wöhrl BM, Goody RS.
    Biochemistry; 1997 Aug 19; 36(33):10292-300. PubMed ID: 9254628
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  • 14. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
    Kerr SG, Anderson KS.
    Biochemistry; 1997 Nov 18; 36(46):14064-70. PubMed ID: 9369478
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  • 15. Impact of clinical reverse transcriptase sequences on the replication capacity of HIV-1 drug-resistant mutants.
    Dykes C, Fox K, Lloyd A, Chiulli M, Morse E, Demeter LM.
    Virology; 2001 Jul 05; 285(2):193-203. PubMed ID: 11437654
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  • 16. Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase.
    Boyer PL, Sarafianos SG, Arnold E, Hughes SH.
    J Virol; 2001 May 05; 75(10):4832-42. PubMed ID: 11312355
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  • 17. Role of a dipeptide insertion between codons 69 and 70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance.
    Mas A, Parera M, Briones C, Soriano V, Martínez MA, Domingo E, Menéndez-Arias L.
    EMBO J; 2000 Nov 01; 19(21):5752-61. PubMed ID: 11060026
    [Abstract] [Full Text] [Related]

  • 18. Endogenous reverse transcriptase assays reveal synergy between combinations of the M184V and other drug resistance-conferring mutations in interactions with nucleoside analog triphosphates.
    Quan Y, Gu Z, Li X, Liang C, Parniak MA, Wainberg MA.
    J Mol Biol; 1998 Mar 27; 277(2):237-47. PubMed ID: 9514745
    [Abstract] [Full Text] [Related]

  • 19. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.
    Gao HQ, Boyer PL, Sarafianos SG, Arnold E, Hughes SH.
    J Mol Biol; 2000 Jul 07; 300(2):403-18. PubMed ID: 10873473
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  • 20. Mutational patterns in the HIV genome and cross-resistance following nucleoside and nucleotide analogue drug exposure.
    Miller V, Larder BA.
    Antivir Ther; 2001 Jul 07; 6 Suppl 3():25-44. PubMed ID: 11678471
    [Abstract] [Full Text] [Related]

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