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627 related items for PubMed ID: 11343250

  • 1. Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver.
    Beuers U, Bilzer M, Chittattu A, Kullak-Ublick GA, Keppler D, Paumgartner G, Dombrowski F.
    Hepatology; 2001 May; 33(5):1206-16. PubMed ID: 11343250
    [Abstract] [Full Text] [Related]

  • 2. Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC alpha-/PKA-dependent mechanism in rat liver.
    Wimmer R, Hohenester S, Pusl T, Denk GU, Rust C, Beuers U.
    Gut; 2008 Oct; 57(10):1448-54. PubMed ID: 18583398
    [Abstract] [Full Text] [Related]

  • 3. Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets.
    Beuers U, Denk GU, Soroka CJ, Wimmer R, Rust C, Paumgartner G, Boyer JL.
    J Biol Chem; 2003 May 16; 278(20):17810-8. PubMed ID: 12626520
    [Abstract] [Full Text] [Related]

  • 4. Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver.
    Dombrowski F, Stieger B, Beuers U.
    Lab Invest; 2006 Feb 16; 86(2):166-74. PubMed ID: 16344857
    [Abstract] [Full Text] [Related]

  • 5. TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCalpha-ezrin pathway.
    Baiocchi L, Tisone G, Russo MA, Longhi C, Palmieri G, Volpe A, Almerighi C, Telesca C, Carbone M, Toti L, De Leonardis F, Angelico M.
    Transpl Int; 2008 Aug 16; 21(8):792-800. PubMed ID: 18435680
    [Abstract] [Full Text] [Related]

  • 6. Modulation of protein kinase C by taurolithocholic acid in isolated rat hepatocytes.
    Beuers U, Probst I, Soroka C, Boyer JL, Kullak-Ublick GA, Paumgartner G.
    Hepatology; 1999 Feb 16; 29(2):477-82. PubMed ID: 9918925
    [Abstract] [Full Text] [Related]

  • 7. Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha.
    Alpini G, Baiocchi L, Glaser S, Ueno Y, Marzioni M, Francis H, Phinizy JL, Angelico M, Lesage G.
    Hepatology; 2002 May 16; 35(5):1041-52. PubMed ID: 11981754
    [Abstract] [Full Text] [Related]

  • 8. Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver.
    Denk GU, Maitz S, Wimmer R, Rust C, Invernizzi P, Ferdinandusse S, Kulik W, Fuchsbichler A, Fickert P, Trauner M, Hofmann AF, Beuers U.
    Hepatology; 2010 Nov 16; 52(5):1758-68. PubMed ID: 21038414
    [Abstract] [Full Text] [Related]

  • 9. Retrieval of the mrp2 gene encoded conjugate export pump from the canalicular membrane contributes to cholestasis induced by tert-butyl hydroperoxide and chloro-dinitrobenzene.
    Schmitt M, Kubitz R, Wettstein M, vom Dahl S, Häussinger D.
    Biol Chem; 2000 Nov 16; 381(5-6):487-95. PubMed ID: 10937881
    [Abstract] [Full Text] [Related]

  • 10. Tauroursodeoxycholic acid activates protein kinase C in isolated rat hepatocytes.
    Beuers U, Throckmorton DC, Anderson MS, Isales CM, Thasler W, Kullak-Ublick GA, Sauter G, Koebe HG, Paumgartner G, Boyer JL.
    Gastroenterology; 1996 May 16; 110(5):1553-63. PubMed ID: 8613063
    [Abstract] [Full Text] [Related]

  • 11. Tauroursodeoxycholic acid stimulates hepatocellular exocytosis and mobilizes extracellular Ca++ mechanisms defective in cholestasis.
    Beuers U, Nathanson MH, Isales CM, Boyer JL.
    J Clin Invest; 1993 Dec 16; 92(6):2984-93. PubMed ID: 8254052
    [Abstract] [Full Text] [Related]

  • 12. Prevention of Mrp2 activity impairment in ethinylestradiol-induced cholestasis by ursodeoxycholate in the rat.
    Crocenzi FA, D'Andrea V, Catania VA, Luquita MG, Pellegrino JM, Ochoa JE, Mottino AD, Sánchez Pozzi EJ.
    Drug Metab Dispos; 2005 Jul 16; 33(7):888-91. PubMed ID: 15843489
    [Abstract] [Full Text] [Related]

  • 13. Impaired activity of the bile canalicular organic anion transporter (Mrp2/cmoat) is not the main cause of ethinylestradiol-induced cholestasis in the rat.
    Koopen NR, Wolters H, Havinga R, Vonk RJ, Jansen PL, Müller M, Kuipers F.
    Hepatology; 1998 Feb 16; 27(2):537-45. PubMed ID: 9462655
    [Abstract] [Full Text] [Related]

  • 14. Biliary secretory function in rats chronically intoxicated with aluminum.
    Gonzalez MA, Roma MG, Bernal CA, Alvarez Mde L, Carrillo MC.
    Toxicol Sci; 2004 May 16; 79(1):189-95. PubMed ID: 14976346
    [Abstract] [Full Text] [Related]

  • 15. Role of mitogen-activated protein kinases in tauroursodeoxycholic acid-induced bile formation in cholestatic rat liver.
    Denk GU, Hohenester S, Wimmer R, Böhland C, Rust C, Beuers U.
    Hepatol Res; 2008 Jul 16; 38(7):717-26. PubMed ID: 18328068
    [Abstract] [Full Text] [Related]

  • 16. Changes in the localization of the rat canalicular conjugate export pump Mrp2 in phalloidin-induced cholestasis.
    Rost D, Kartenbeck J, Keppler D.
    Hepatology; 1999 Mar 16; 29(3):814-21. PubMed ID: 10051484
    [Abstract] [Full Text] [Related]

  • 17. Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited.
    Paumgartner G, Beuers U.
    Hepatology; 2002 Sep 16; 36(3):525-31. PubMed ID: 12198643
    [Abstract] [Full Text] [Related]

  • 18. Regulation of rat organic anion transporters in bile salt-induced cholestatic hepatitis: effect of ursodeoxycholate.
    Rost D, Herrmann T, Sauer P, Schmidts HL, Stieger B, Meier PJ, Stremmel W, Stiehl A.
    Hepatology; 2003 Jul 16; 38(1):187-95. PubMed ID: 12830001
    [Abstract] [Full Text] [Related]

  • 19. Tauroursodeoxycholic acid protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways.
    Schoemaker MH, Conde de la Rosa L, Buist-Homan M, Vrenken TE, Havinga R, Poelstra K, Haisma HJ, Jansen PL, Moshage H.
    Hepatology; 2004 Jun 16; 39(6):1563-73. PubMed ID: 15185297
    [Abstract] [Full Text] [Related]

  • 20. Tauroursodeoxycholic acid reduces bile acid-induced apoptosis by modulation of AP-1.
    Pusl T, Vennegeerts T, Wimmer R, Denk GU, Beuers U, Rust C.
    Biochem Biophys Res Commun; 2008 Feb 29; 367(1):208-12. PubMed ID: 18164257
    [Abstract] [Full Text] [Related]

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