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70 related items for PubMed ID: 11343802

  • 1. In vitro activity of MEKK2 and MEKK3 in detergents is a function of a valine to serine difference in the catalytic domain.
    Widmann C, Sather S, Oyer R, Johnson GL, Dreskin SC.
    Biochim Biophys Acta; 2001 May 05; 1547(1):167-73. PubMed ID: 11343802
    [Abstract] [Full Text] [Related]

  • 2. PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway.
    Nakamura K, Johnson GL.
    J Biol Chem; 2003 Sep 26; 278(39):36989-92. PubMed ID: 12912994
    [Abstract] [Full Text] [Related]

  • 3. Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo.
    Deacon K, Blank JL.
    J Biol Chem; 1997 May 30; 272(22):14489-96. PubMed ID: 9162092
    [Abstract] [Full Text] [Related]

  • 4. MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway.
    Sun W, Kesavan K, Schaefer BC, Garrington TP, Ware M, Johnson NL, Gelfand EW, Johnson GL.
    J Biol Chem; 2001 Feb 16; 276(7):5093-100. PubMed ID: 11073940
    [Abstract] [Full Text] [Related]

  • 5. MEK kinase 2 binds and activates protein kinase C-related kinase 2. Bifurcation of kinase regulatory pathways at the level of an MAPK kinase kinase.
    Sun W, Vincent S, Settleman J, Johnson GL.
    J Biol Chem; 2000 Aug 11; 275(32):24421-8. PubMed ID: 10818102
    [Abstract] [Full Text] [Related]

  • 6. Mutations in protein kinase subdomain X differentially affect MEKK2 and MEKK1 activity.
    Huang J, Tu Z, Lee FS.
    Biochem Biophys Res Commun; 2003 Apr 04; 303(2):532-40. PubMed ID: 12659851
    [Abstract] [Full Text] [Related]

  • 7. WNK1 activates ERK5 by an MEKK2/3-dependent mechanism.
    Xu BE, Stippec S, Lenertz L, Lee BH, Zhang W, Lee YK, Cobb MH.
    J Biol Chem; 2004 Feb 27; 279(9):7826-31. PubMed ID: 14681216
    [Abstract] [Full Text] [Related]

  • 8. Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis.
    Hammaker DR, Boyle DL, Chabaud-Riou M, Firestein GS.
    J Immunol; 2004 Feb 01; 172(3):1612-8. PubMed ID: 14734742
    [Abstract] [Full Text] [Related]

  • 9. MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression.
    Su B, Cheng J, Yang J, Guo Z.
    J Biol Chem; 2001 May 04; 276(18):14784-90. PubMed ID: 11278622
    [Abstract] [Full Text] [Related]

  • 10. Phosphorylation of serine 526 is required for MEKK3 activity, and association with 14-3-3 blocks dephosphorylation.
    Fritz A, Brayer KJ, McCormick N, Adams DG, Wadzinski BE, Vaillancourt RR.
    J Biol Chem; 2006 Mar 10; 281(10):6236-45. PubMed ID: 16407301
    [Abstract] [Full Text] [Related]

  • 11. Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways.
    Zhang D, Facchinetti V, Wang X, Huang Q, Qin J, Su B.
    EMBO J; 2006 Jan 11; 25(1):97-107. PubMed ID: 16362041
    [Abstract] [Full Text] [Related]

  • 12. MEKK2 and MEKK3 orchestrate multiple signals to regulate Hippo pathway.
    Lu J, Hu Z, Deng Y, Wu Q, Wu M, Song H.
    J Biol Chem; 2021 Jan 11; 296():100400. PubMed ID: 33571521
    [Abstract] [Full Text] [Related]

  • 13. Homogeneous time-resolved fluorescence resonance energy transfer assay for measurement of Phox/Bem1p (PB1) domain heterodimerization.
    Nakamura K, Zawistowski JS, Hughes MA, Sexton JZ, Yeh LA, Johnson GL, Scott JE.
    J Biomol Screen; 2008 Jun 11; 13(5):396-405. PubMed ID: 18480472
    [Abstract] [Full Text] [Related]

  • 14. MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells.
    Garrington TP, Ishizuka T, Papst PJ, Chayama K, Webb S, Yujiri T, Sun W, Sather S, Russell DM, Gibson SB, Keller G, Gelfand EW, Johnson GL.
    EMBO J; 2000 Oct 16; 19(20):5387-95. PubMed ID: 11032806
    [Abstract] [Full Text] [Related]

  • 15. Restoration of NF-kappaB activation by tumor necrosis factor alpha receptor complex-targeted MEKK3 in receptor-interacting protein-deficient cells.
    Blonska M, You Y, Geleziunas R, Lin X.
    Mol Cell Biol; 2004 Dec 16; 24(24):10757-65. PubMed ID: 15572679
    [Abstract] [Full Text] [Related]

  • 16. MEKK3 interacts with the PA28 gamma regulatory subunit of the proteasome.
    Hagemann C, Patel R, Blank JL.
    Biochem J; 2003 Jul 01; 373(Pt 1):71-9. PubMed ID: 12650640
    [Abstract] [Full Text] [Related]

  • 17. Protein kinase C-associated kinase can activate NFkappaB in both a kinase-dependent and a kinase-independent manner.
    Moran ST, Haider K, Ow Y, Milton P, Chen L, Pillai S.
    J Biol Chem; 2003 Jun 13; 278(24):21526-33. PubMed ID: 12676934
    [Abstract] [Full Text] [Related]

  • 18. 14-3-3 proteins interact with specific MEK kinases.
    Fanger GR, Widmann C, Porter AC, Sather S, Johnson GL, Vaillancourt RR.
    J Biol Chem; 1998 Feb 06; 273(6):3476-83. PubMed ID: 9452471
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of mitogen-activated kinase kinase kinase 3 activity through phosphorylation by the serum- and glucocorticoid-induced kinase 1.
    Chun J, Kwon T, Kim DJ, Park I, Chung G, Lee EJ, Hong SK, Chang SI, Kim HY, Kang SS.
    J Biochem; 2003 Jan 06; 133(1):103-8. PubMed ID: 12761204
    [Abstract] [Full Text] [Related]

  • 20. MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts.
    Kesavan K, Lobel-Rice K, Sun W, Lapadat R, Webb S, Johnson GL, Garrington TP.
    J Cell Physiol; 2004 Apr 06; 199(1):140-8. PubMed ID: 14978743
    [Abstract] [Full Text] [Related]

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