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246 related items for PubMed ID: 11350900

  • 1. Expression of DT-diaphorase and cytochrome P450 reductase correlates with mitomycin C activity in human bladder tumors.
    Gan Y, Mo Y, Kalns JE, Lu J, Danenberg K, Danenberg P, Wientjes MG, Au JL.
    Clin Cancer Res; 2001 May; 7(5):1313-9. PubMed ID: 11350900
    [Abstract] [Full Text] [Related]

  • 2. Distribution of DT-diaphorase and reduced nicotinamide adenine dinucleotide phosphate: cytochrome p450 oxidoreductase in bladder tissues and tumors.
    Li D, Gan Y, Wientjes MG, Badalament RA, Au JL.
    J Urol; 2001 Dec; 166(6):2500-5. PubMed ID: 11696818
    [Abstract] [Full Text] [Related]

  • 3. [DT-diaphorase].
    Mikami K, Shirakusa T, Tsuruo T.
    Gan To Kagaku Ryoho; 1997 Sep; 24(11):1606-10. PubMed ID: 9309161
    [Abstract] [Full Text] [Related]

  • 4. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
    Traver RD, Horikoshi T, Danenberg KD, Stadlbauer TH, Danenberg PV, Ross D, Gibson NW.
    Cancer Res; 1992 Feb 15; 52(4):797-802. PubMed ID: 1737339
    [Abstract] [Full Text] [Related]

  • 5. DT-diaphorase as a critical determinant of sensitivity to mitomycin C in human colon and gastric carcinoma cell lines.
    Mikami K, Naito M, Tomida A, Yamada M, Sirakusa T, Tsuruo T.
    Cancer Res; 1996 Jun 15; 56(12):2823-6. PubMed ID: 8665520
    [Abstract] [Full Text] [Related]

  • 6. Predicting tumor responses to mitomycin C on the basis of DT-diaphorase activity or drug metabolism by tumor homogenates: implications for enzyme-directed bioreductive drug development.
    Phillips RM, Burger AM, Loadman PM, Jarrett CM, Swaine DJ, Fiebig HH.
    Cancer Res; 2000 Nov 15; 60(22):6384-90. PubMed ID: 11103802
    [Abstract] [Full Text] [Related]

  • 7. Viral delivery of P450 reductase recapitulates the ability of constitutive overexpression of reductase enzymes to potentiate the activity of mitomycin C in human breast cancer xenografts.
    Cowen RL, Patterson AV, Telfer BA, Airley RE, Hobbs S, Phillips RM, Jaffar M, Stratford IJ, Williams KJ.
    Mol Cancer Ther; 2003 Sep 15; 2(9):901-9. PubMed ID: 14555709
    [Abstract] [Full Text] [Related]

  • 8. DT-diaphorase as a target enzyme for biochemical modulation of mitomycin C.
    Saeki S, Nishiyama M, Toge T.
    Hiroshima J Med Sci; 1995 Sep 15; 44(3):55-63. PubMed ID: 8567314
    [Abstract] [Full Text] [Related]

  • 9. Immunohistochemical analysis of NAD(P)H:quinone oxidoreductase and NADPH cytochrome P450 reductase in human superficial bladder tumours: relationship between tumour enzymology and clinical outcome following intravesical mitomycin C therapy.
    Basu S, Brown JE, Flannigan GM, Gill JH, Loadman PM, Martin SW, Naylor B, Scally AJ, Seargent JM, Shah T, Puri R, Phillips RM.
    Int J Cancer; 2004 May 01; 109(5):703-9. PubMed ID: 14999778
    [Abstract] [Full Text] [Related]

  • 10. Tumor-specific synergistic therapy of mitomycin C: modulation of bioreductive activation.
    Sakamoto N, Toge T, Nishiyama M.
    Hiroshima J Med Sci; 1997 Jun 01; 46(2):67-73. PubMed ID: 9232934
    [Abstract] [Full Text] [Related]

  • 11. Mitomycin C resistance induced by TCF-3 overexpression in gastric cancer cell line MKN28 is associated with DT-diaphorase down-regulation.
    Sagara N, Katoh M.
    Cancer Res; 2000 Nov 01; 60(21):5959-62. PubMed ID: 11085512
    [Abstract] [Full Text] [Related]

  • 12. Expression of the prodrug-activating enzyme DT-diaphorase via Ad5 delivery to human colon carcinoma cells in vitro.
    Misra V, Klamut HJ, Rauth AM.
    Cancer Gene Ther; 2002 Feb 01; 9(2):209-17. PubMed ID: 11857040
    [Abstract] [Full Text] [Related]

  • 13. [Mechanism of resistance to mitomycin C in a human bladder cancer cell line].
    Xu B, Sun Y, Singh SV.
    Zhonghua Zhong Liu Za Zhi; 1995 Sep 01; 17(5):343-6. PubMed ID: 8697971
    [Abstract] [Full Text] [Related]

  • 14. Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase.
    Wang X, Doherty GP, Leith MK, Curphey TJ, Begleiter A.
    Br J Cancer; 1999 Jun 01; 80(8):1223-30. PubMed ID: 10376975
    [Abstract] [Full Text] [Related]

  • 15. Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: relationship to the response of lung tumor xenografts to mitomycin Cł.
    Malkinson AM, Siegel D, Forrest GL, Gazdar AF, Oie HK, Chan DC, Bunn PA, Mabry M, Dykes DJ, Harrison SD.
    Cancer Res; 1992 Sep 01; 52(17):4752-7. PubMed ID: 1324793
    [Abstract] [Full Text] [Related]

  • 16. The importance of DT-diaphorase in mitomycin C resistance in human colon cancer cell lines.
    Lambert PA, Kang Y, Greaves B, Perry RR.
    J Surg Res; 1998 Dec 01; 80(2):177-81. PubMed ID: 9878310
    [Abstract] [Full Text] [Related]

  • 17. Pharmacodynamics of mitomycin C in cultured human bladder tumors.
    Schmittgen TD, Wientjes MG, Badalament RA, Au JL.
    Cancer Res; 1991 Aug 01; 51(15):3849-56. PubMed ID: 1906778
    [Abstract] [Full Text] [Related]

  • 18. Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells.
    Baumann RP, Hodnick WF, Seow HA, Belcourt MF, Rockwell S, Sherman DH, Sartorelli AC.
    Cancer Res; 2001 Nov 01; 61(21):7770-6. PubMed ID: 11691791
    [Abstract] [Full Text] [Related]

  • 19. Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines.
    Beall HD, Murphy AM, Siegel D, Hargreaves RH, Butler J, Ross D.
    Mol Pharmacol; 1995 Sep 01; 48(3):499-504. PubMed ID: 7565631
    [Abstract] [Full Text] [Related]

  • 20. DT-diaphorase: a target for new anticancer drugs.
    Danson S, Ward TH, Butler J, Ranson M.
    Cancer Treat Rev; 2004 Aug 01; 30(5):437-49. PubMed ID: 15245776
    [Abstract] [Full Text] [Related]

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