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Journal Abstract Search

109 related items for PubMed ID: 11354363

  • 1.
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  • 3. Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity (II): Optimization of the C3 amino substituent.
    Hirst GC, Aquino C, Birkemo L, Croom DK, Dezube M, Dougherty RW, Ervin GN, Grizzle MK, Henke B, James MK, Johnson MF, Momtahen T, Queen KL, Sherrill RG, Szewczyk J, Willson TM, Sugg EE.
    J Med Chem; 1996 Dec 20; 39(26):5236-45. PubMed ID: 8978852
    [Abstract] [Full Text] [Related]

  • 4. ARL 15849: a selective CCK-A agonist with anorectic activity in the rat and dog.
    Simmons RD, Kaiser FC, Pierson ME, Rosamond JR.
    Pharmacol Biochem Behav; 1998 Feb 20; 59(2):439-44. PubMed ID: 9476993
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  • 5. Optimization of 3-(1H-indazol-3-ylmethyl)-1,5-benzodiazepines as potent, orally active CCK-A agonists.
    Henke BR, Aquino CJ, Birkemo LS, Croom DK, Dougherty RW, Ervin GN, Grizzle MK, Hirst GC, James MK, Johnson MF, Queen KL, Sherrill RG, Sugg EE, Suh EM, Szewczyk JW, Unwalla RJ, Yingling J, Willson TM.
    J Med Chem; 1997 Aug 15; 40(17):2706-25. PubMed ID: 9276016
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  • 6. Tifluadom, a kappa-opiate agonist, acts as a peripheral cholecystokinin receptor antagonist.
    Chang RS, Lotti VJ, Chen TB, Keegan ME.
    Neurosci Lett; 1986 Dec 12; 72(2):211-4. PubMed ID: 3027627
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  • 7. CCK peptides with combined features of hexa- and tetrapeptide CCK-A agonists.
    Pierson ME, Comstock JM, Simmons RD, Julien R, Kaiser F, Rosamond JD.
    J Med Chem; 2000 Jun 15; 43(12):2350-5. PubMed ID: 10882360
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  • 8. 3-(1H-indazol-3-ylmethyl)-1,5-benzodiazepines: CCK-A agonists that demonstrate oral activity as satiety agents.
    Henke BR, Willson TM, Sugg EE, Croom DK, Dougherty RW, Queen KL, Birkemo LS, Ervin GN, Grizzle MK, Johnson MF, James MK.
    J Med Chem; 1996 Jul 05; 39(14):2655-8. PubMed ID: 8709093
    [No Abstract] [Full Text] [Related]

  • 9. 3-[2-(N-phenylacetamide)]-1,5-benzodiazepines: orally active, binding selective CCK-A agonists.
    Willson TM, Henke BR, Momtahen TM, Myers PL, Sugg EE, Unwalla RJ, Croom DK, Dougherty RW, Grizzle MK, Johnson MF, Queen KL, Rimele TJ, Yingling JD, James MK.
    J Med Chem; 1996 Jul 19; 39(15):3030-4. PubMed ID: 8709137
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  • 10. Synthesis and biological activity of CCK heptapeptide analogues. Effects of conformational constraints and standard modifications on receptor subtype selectivity, functional activity in vitro, and appetite suppression in vivo.
    Holladay MW, Bennett MJ, Tufano MD, Lin CW, Asin KE, Witte DG, Miller TR, Bianchi BR, Nikkel AL, Bednarz L.
    J Med Chem; 1992 Aug 07; 35(16):2919-28. PubMed ID: 1501220
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of potent, selective, hexapeptide CCK-A agonist anorectic agents.
    Pierson ME, Comstock JM, Simmons RD, Kaiser F, Julien R, Zongrone J, Rosamond JD.
    J Med Chem; 1997 Dec 19; 40(26):4302-7. PubMed ID: 9435899
    [Abstract] [Full Text] [Related]

  • 12. Cholecystokinin antagonists. Synthesis and biological evaluation of 4-substituted 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepines.
    Bock MG, DiPardo RM, Evans BE, Rittle KE, Veber DF, Freidinger RM, Chang RS, Lotti VJ.
    J Med Chem; 1988 Jan 19; 31(1):176-81. PubMed ID: 3336017
    [Abstract] [Full Text] [Related]

  • 13. Biochemical and pharmacological characterization of an extremely potent and selective nonpeptide cholecystokinin antagonist.
    Chang RS, Lotti VJ.
    Proc Natl Acad Sci U S A; 1986 Jul 19; 83(13):4923-6. PubMed ID: 3014520
    [Abstract] [Full Text] [Related]

  • 14. FPL 14294: a novel CCK-8 agonist with potent intranasal anorectic activity in the rat.
    Simmons RD, Blosser JC, Rosamond JR.
    Pharmacol Biochem Behav; 1994 Mar 19; 47(3):701-8. PubMed ID: 8208791
    [Abstract] [Full Text] [Related]

  • 15. Cholecystokinin-A receptor ligands based on the kappa-opioid agonist tifluadom.
    Bock MG, DiPardo RM, Evans BE, Rittle KE, Whitter WL, Veber DF, Freidinger RM, Chang RS, Chen TB, Lotti VJ.
    J Med Chem; 1990 Jan 19; 33(1):450-5. PubMed ID: 2153212
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazepines as cholecystokinin-B receptor antagonists.
    Ursini A, Capelli AM, Carr RA, Cassarà P, Corsi M, Curcuruto O, Curotto G, Dal Cin M, Davalli S, Donati D, Feriani A, Finch H, Finizia G, Gaviraghi G, Marien M, Pentassuglia G, Polinelli S, Ratti E, Reggiani AM, Tarzia G, Tedesco G, Tranquillini ME, Trist DG, Van Amsterdam FT.
    J Med Chem; 2000 Oct 05; 43(20):3596-613. PubMed ID: 11020274
    [Abstract] [Full Text] [Related]

  • 17. Beta-carbolines selectively antagonize the cholecystokinin action in isolated guinea-pig gallbladder muscle.
    Kubota K, Itonaga M.
    Jpn J Pharmacol; 1986 Dec 05; 42(4):501-6. PubMed ID: 3807051
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  • 18. The use of receptor desensitization to analyse CCKA and CCKB/gastrin receptors coupled to contraction in guinea-pig stomach muscle.
    Bishop LA, Gerskowitch VP, Hull RA, Shankley NP, Black JW.
    Br J Pharmacol; 1995 Jan 05; 114(2):339-48. PubMed ID: 7881733
    [Abstract] [Full Text] [Related]

  • 19. Relationship between dihedral angles of N1 and C9 substituents in 1,4-benzodiazepines and dual cholecystokinin-A and -B antagonistic activities.
    Tabuchi S, Nakanishi I, Satoh Y.
    Bioorg Med Chem Lett; 1998 Jun 16; 8(12):1449-54. PubMed ID: 9873368
    [Abstract] [Full Text] [Related]

  • 20. 5-(Piperidin-2-yl)- and 5-(homopiperidin-2-yl)-1,4-benzodiazepines: high-affinity, basic ligands for the cholecystokinin-B receptor.
    Castro JL, Broughton HB, Russell MG, Rathbone D, Watt AP, Ball RG, Chapman KL, Patel S, Smith AJ, Marshall GR, Matassa VG.
    J Med Chem; 1997 Aug 01; 40(16):2491-501. PubMed ID: 9258356
    [Abstract] [Full Text] [Related]

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