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173 related items for PubMed ID: 11356850

  • 1. Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice.
    Furuta M, Zhou A, Webb G, Carroll R, Ravazzola M, Orci L, Steiner DF.
    J Biol Chem; 2001 Jul 20; 276(29):27197-202. PubMed ID: 11356850
    [Abstract] [Full Text] [Related]

  • 2. Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2.
    Furuta M, Carroll R, Martin S, Swift HH, Ravazzola M, Orci L, Steiner DF.
    J Biol Chem; 1998 Feb 06; 273(6):3431-7. PubMed ID: 9452465
    [Abstract] [Full Text] [Related]

  • 3. Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide.
    Rouillé Y, Martin S, Steiner DF.
    J Biol Chem; 1995 Nov 03; 270(44):26488-96. PubMed ID: 7592866
    [Abstract] [Full Text] [Related]

  • 4. Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects.
    Zhu X, Zhou A, Dey A, Norrbom C, Carroll R, Zhang C, Laurent V, Lindberg I, Ugleholdt R, Holst JJ, Steiner DF.
    Proc Natl Acad Sci U S A; 2002 Aug 06; 99(16):10293-8. PubMed ID: 12145326
    [Abstract] [Full Text] [Related]

  • 5. Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
    Rouillé Y, Westermark G, Martin SK, Steiner DF.
    Proc Natl Acad Sci U S A; 1994 Apr 12; 91(8):3242-6. PubMed ID: 8159732
    [Abstract] [Full Text] [Related]

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  • 7. Altered proglucagon processing in an alpha-cell line derived from prohormone convertase 2 null mouse islets.
    Webb GC, Dey A, Wang J, Stein J, Milewski M, Steiner DF.
    J Biol Chem; 2004 Jul 23; 279(30):31068-75. PubMed ID: 15143067
    [Abstract] [Full Text] [Related]

  • 8. Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.
    Furuta M, Yano H, Zhou A, Rouillé Y, Holst JJ, Carroll R, Ravazzola M, Orci L, Furuta H, Steiner DF.
    Proc Natl Acad Sci U S A; 1997 Jun 24; 94(13):6646-51. PubMed ID: 9192619
    [Abstract] [Full Text] [Related]

  • 9. Proglucagon processing in islet and intestinal cell lines.
    Tucker JD, Dhanvantari S, Brubaker PL.
    Regul Pept; 1996 Apr 09; 62(1):29-35. PubMed ID: 8738879
    [Abstract] [Full Text] [Related]

  • 10. Proglucagon processing profile in canine L cells expressing endogenous prohormone convertase 1/3 and prohormone convertase 2.
    Damholt AB, Buchan AM, Holst JJ, Kofod H.
    Endocrinology; 1999 Oct 09; 140(10):4800-8. PubMed ID: 10499540
    [Abstract] [Full Text] [Related]

  • 11. Role of the prohormone convertase PC2 in the processing of proglucagon to glucagon.
    Rouillé Y, Bianchi M, Irminger JC, Halban PA.
    FEBS Lett; 1997 Aug 11; 413(1):119-23. PubMed ID: 9287128
    [Abstract] [Full Text] [Related]

  • 12. Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro.
    Rothenberg ME, Eilertson CD, Klein K, Zhou Y, Lindberg I, McDonald JK, Mackin RB, Noe BD.
    J Biol Chem; 1995 Apr 28; 270(17):10136-46. PubMed ID: 7730317
    [Abstract] [Full Text] [Related]

  • 13. Immunological detection of prohormone convertases in two different proglucagon processing cell lines.
    Blache P, Le-Nguyen D, Boegner-Lemoine C, Cohen-Solal A, Bataille D, Kervran A.
    FEBS Lett; 1994 May 09; 344(1):65-8. PubMed ID: 8181567
    [Abstract] [Full Text] [Related]

  • 14. Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.
    Ugleholdt R, Zhu X, Deacon CF, Ørskov C, Steiner DF, Holst JJ.
    Endocrinology; 2004 Mar 09; 145(3):1349-55. PubMed ID: 14630721
    [Abstract] [Full Text] [Related]

  • 15. The role of prohormone convertases PC1 (PC3) and PC2 in the cell-specific processing of proglucagon.
    Mineo I, Matsumura T, Shingu R, Namba M, Kuwajima M, Matsuzawa Y.
    Biochem Biophys Res Commun; 1995 Feb 15; 207(2):646-51. PubMed ID: 7864855
    [Abstract] [Full Text] [Related]

  • 16. Glucagon replacement via micro-osmotic pump corrects hypoglycemia and alpha-cell hyperplasia in prohormone convertase 2 knockout mice.
    Webb GC, Akbar MS, Zhao C, Swift HH, Steiner DF.
    Diabetes; 2002 Feb 15; 51(2):398-405. PubMed ID: 11812747
    [Abstract] [Full Text] [Related]

  • 17. A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice.
    Wideman RD, Covey SD, Webb GC, Drucker DJ, Kieffer TJ.
    Diabetes; 2007 Nov 15; 56(11):2744-52. PubMed ID: 17698597
    [Abstract] [Full Text] [Related]

  • 18. Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased alpha-cell proliferation, and islet neogenesis.
    Vincent M, Guz Y, Rozenberg M, Webb G, Furuta M, Steiner D, Teitelman G.
    Endocrinology; 2003 Sep 15; 144(9):4061-9. PubMed ID: 12933680
    [Abstract] [Full Text] [Related]

  • 19. Dynamic modulation of prohormone convertase 2 (PC2)-mediated precursor processing by 7B2 protein: preferential effect on glucagon synthesis.
    Helwig M, Lee SN, Hwang JR, Ozawa A, Medrano JF, Lindberg I.
    J Biol Chem; 2011 Dec 09; 286(49):42504-42513. PubMed ID: 22013069
    [Abstract] [Full Text] [Related]

  • 20. Significance of prohormone convertase 2, PC2, mediated initial cleavage at the proglucagon interdomain site, Lys70-Arg71, to generate glucagon.
    Dey A, Lipkind GM, Rouillé Y, Norrbom C, Stein J, Zhang C, Carroll R, Steiner DF.
    Endocrinology; 2005 Feb 09; 146(2):713-27. PubMed ID: 15528303
    [Abstract] [Full Text] [Related]

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