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Journal Abstract Search

263 related items for PubMed ID: 11368333

  • 1. Characterization of cytochrome P450 2A4 and 2A5-catalyzed 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism.
    Felicia ND, Rekha GK, Murphy SE.
    Arch Biochem Biophys; 2000 Dec 15; 384(2):418-24. PubMed ID: 11368333
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  • 2. Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13.
    Jalas JR, Ding X, Murphy SE.
    Drug Metab Dispos; 2003 Oct 15; 31(10):1199-202. PubMed ID: 12975327
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  • 3. Synthesis of stereospecifically deuterated 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) iastereomers and metabolism by A/J mouse lung microsomes and cytochrome p450 2A5.
    Jalas JR, Hecht SS.
    Chem Res Toxicol; 2003 Jun 15; 16(6):782-93. PubMed ID: 12807362
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  • 6. Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
    Patten CJ, Smith TJ, Friesen MJ, Tynes RE, Yang CS, Murphy SE.
    Carcinogenesis; 1997 Aug 15; 18(8):1623-30. PubMed ID: 9276639
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  • 11. Metabolic activation of the tobacco carcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone by cytochrome P450 2A13 in human fetal nasal microsomes.
    Wong HL, Zhang X, Zhang QY, Gu J, Ding X, Hecht SS, Murphy SE.
    Chem Res Toxicol; 2005 Jun 15; 18(6):913-8. PubMed ID: 15962925
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  • 12. Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
    Smith TJ, Stoner GD, Yang CS.
    Cancer Res; 1995 Dec 01; 55(23):5566-73. PubMed ID: 7585636
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  • 13. Analysis of CYP2A contributions to metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human peripheral lung microsomes.
    Brown PJ, Bedard LL, Reid KR, Petsikas D, Massey TE.
    Drug Metab Dispos; 2007 Nov 01; 35(11):2086-94. PubMed ID: 17717079
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  • 14. Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas.
    Miyazaki M, Yamazaki H, Takeuchi H, Saoo K, Yokohira M, Masumura K, Nohmi T, Funae Y, Imaida K, Kamataki T.
    Carcinogenesis; 2005 Nov 01; 26(11):1947-55. PubMed ID: 15958517
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  • 15. Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-butanone metabolism by cytochrome P450 2B6.
    Dicke KE, Skrlin SM, Murphy SE.
    Drug Metab Dispos; 2005 Dec 01; 33(12):1760-4. PubMed ID: 16174803
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  • 18. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
    Smith TJ, Guo Z, Gonzalez FJ, Guengerich FP, Stoner GD, Yang CS.
    Cancer Res; 1992 Apr 01; 52(7):1757-63. PubMed ID: 1312898
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  • 20. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate.
    Smith TJ, Guo Z, Guengerich FP, Yang CS.
    Carcinogenesis; 1996 Apr 01; 17(4):809-13. PubMed ID: 8625495
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