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Journal Abstract Search

263 related items for PubMed ID: 11368333

  • 21. Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate.
    Smith TJ, Guo Z, Li C, Ning SM, Thomas PE, Yang CS.
    Cancer Res; 1993 Jul 15; 53(14):3276-82. PubMed ID: 8324738
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  • 22. Preferential metabolic activation of N-nitrosopiperidine as compared to its structural homologue N-nitrosopyrrolidine by rat nasal mucosal microsomes.
    Wong HL, Murphy SE, Hecht SS.
    Chem Res Toxicol; 2003 Oct 15; 16(10):1298-305. PubMed ID: 14565771
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  • 23. Nicotine 5'-oxidation and methyl oxidation by P450 2A enzymes.
    Murphy SE, Raulinaitis V, Brown KM.
    Drug Metab Dispos; 2005 Aug 15; 33(8):1166-73. PubMed ID: 15860657
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  • 24. Development of a Salmonella tester strain sensitive to promutagenic N-nitrosamines: expression of recombinant CYP2A6 and human NADPH-cytochrome P450 reductase in S. typhimurium YG7108.
    Kushida H, Fujita K, Suzuki A, Yamada M, Nohmi T, Kamataki T.
    Mutat Res; 2000 Nov 20; 471(1-2):135-43. PubMed ID: 11080669
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  • 25. Retroviral mediated expression of human cytochrome P450 2A6 in C3H/10T1/2 cells confers transformability by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Tiano HF, Hosokawa M, Chulada PC, Smith PB, Wang RL, Gonzalez FJ, Crespi CL, Langenbach R.
    Carcinogenesis; 1993 Jul 20; 14(7):1421-7. PubMed ID: 8330360
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  • 26. 11Beta-hydroxysteroid dehydrogenase responsible for carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes.
    Maser E.
    Cancer Res; 1998 Jul 15; 58(14):2996-3003. PubMed ID: 9679962
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  • 27. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytochrome P450IIB1 in a reconstituted system.
    Guo Z, Smith TJ, Ishizaki H, Yang CS.
    Carcinogenesis; 1991 Dec 15; 12(12):2277-82. PubMed ID: 1747927
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  • 28. Interaction of aflatoxin B1 with cytochrome P450 2A5 and its mutants: correlation with metabolic activation and toxicity.
    Pelkonen P, Lang MA, Negishi M, Wild CP, Juvonen RO.
    Chem Res Toxicol; 1997 Jan 15; 10(1):85-90. PubMed ID: 9074807
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  • 29. Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.
    Koenigs LL, Peter RM, Thompson SJ, Rettie AE, Trager WF.
    Drug Metab Dispos; 1997 Dec 15; 25(12):1407-15. PubMed ID: 9394031
    [Abstract] [Full Text] [Related]

  • 30. Metabolic effects of CYP2A6 and CYP2A13 on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced gene mutation--a mammalian cell-based mutagenesis approach.
    Chiang HC, Wang CY, Lee HL, Tsou TC.
    Toxicol Appl Pharmacol; 2011 Jun 01; 253(2):145-52. PubMed ID: 21473878
    [Abstract] [Full Text] [Related]

  • 31. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats.
    Guo Z, Smith TJ, Thomas PE, Yang CS.
    Arch Biochem Biophys; 1992 Oct 01; 298(1):279-86. PubMed ID: 1524438
    [Abstract] [Full Text] [Related]

  • 32. Effects of 8-methoxypsoralen on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.
    Feng M, Zhang H, Cao B, Liu S, Mao J, Zhang Q.
    Drug Metab Pharmacokinet; 2015 Aug 01; 30(4):314-20. PubMed ID: 26210672
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  • 33. CYP2A13: variable expression and role in human lung microsomal metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Zhang X, D'Agostino J, Wu H, Zhang QY, von Weymarn L, Murphy SE, Ding X.
    J Pharmacol Exp Ther; 2007 Nov 01; 323(2):570-8. PubMed ID: 17671098
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  • 34. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM, Wester MR, Aramsombatdee E, Raucy JL.
    Arch Biochem Biophys; 1998 May 01; 353(1):16-28. PubMed ID: 9578596
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  • 35. Molecular modelling of CYP2A enzymes: application to metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Jalas JR, Seetharaman M, Hecht SS, Murphy SE.
    Xenobiotica; 2004 Jun 01; 34(6):515-33. PubMed ID: 15277013
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  • 36. Roles of cytochromes P450 1A2, 2A6, and 2C8 in 5-fluorouracil formation from tegafur, an anticancer prodrug, in human liver microsomes.
    Komatsu T, Yamazaki H, Shimada N, Nakajima M, Yokoi T.
    Drug Metab Dispos; 2000 Dec 01; 28(12):1457-63. PubMed ID: 11095583
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  • 37. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
    Yamazaki H, Inui Y, Yun CH, Guengerich FP, Shimada T.
    Carcinogenesis; 1992 Oct 01; 13(10):1789-94. PubMed ID: 1423839
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  • 38. Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and N'- nitrosonornicotine in human hepatic microsomes.
    Staretz ME, Murphy SE, Patten CJ, Nunes MG, Koehl W, Amin S, Koenig LA, Guengerich FP, Hecht SS.
    Drug Metab Dispos; 1997 Feb 01; 25(2):154-62. PubMed ID: 9029045
    [Abstract] [Full Text] [Related]

  • 39. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes.
    Collazo NR, Sultatos LG.
    Biochem Pharmacol; 1995 Nov 27; 50(11):1933-41. PubMed ID: 8615875
    [Abstract] [Full Text] [Related]

  • 40. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen, by rabbit nasal microsomes and cytochrome P450s NMa and NMb.
    Hong JY, Ding X, Smith TJ, Coon MJ, Yang CS.
    Carcinogenesis; 1992 Nov 27; 13(11):2141-4. PubMed ID: 1423886
    [Abstract] [Full Text] [Related]

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