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71 related items for PubMed ID: 11370669

  • 1. Role of THR501 residue in substrate binding and catalytic activity of cytochrome P4501A1.
    Cvrk T, Strobel HW.
    Arch Biochem Biophys; 2001 May 01; 389(1):31-40. PubMed ID: 11370669
    [Abstract] [Full Text] [Related]

  • 2. Photoaffinity labeling of cytochrome P4501A1 with azidocumene: identification of cumene hydroperoxide binding region.
    Cvrk T, Strobel HW.
    Arch Biochem Biophys; 1998 Jan 01; 349(1):95-104. PubMed ID: 9439587
    [Abstract] [Full Text] [Related]

  • 3. Role of LYS271 and LYS279 residues in the interaction of cytochrome P4501A1 with NADPH-cytochrome P450 reductase.
    Cvrk T, Strobel HW.
    Arch Biochem Biophys; 2001 Jan 15; 385(2):290-300. PubMed ID: 11368010
    [Abstract] [Full Text] [Related]

  • 4. Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450.
    Matsunaga I, Ueda A, Sumimoto T, Ichihara K, Ayata M, Ogura H.
    Arch Biochem Biophys; 2001 Oct 01; 394(1):45-53. PubMed ID: 11566026
    [Abstract] [Full Text] [Related]

  • 5. Propranolol hydroxylation and N-desisopropylation by cytochrome P4502D6: studies using the yeast-expressed enzyme and NADPH/O2 and cumene hydroperoxide-supported reactions.
    Bichara N, Ching MS, Blake CL, Ghabrial H, Smallwood RA.
    Drug Metab Dispos; 1996 Jan 01; 24(1):112-8. PubMed ID: 8825198
    [Abstract] [Full Text] [Related]

  • 6. Cumene hydroperoxide-supported demethylation reactions catalyzed by cytochrome P450 2B4 lacking the NH2-terminal sequence.
    Zhang Y, Pernecky SJ.
    Biochem Biophys Res Commun; 1999 Apr 29; 258(1):32-8. PubMed ID: 10222230
    [Abstract] [Full Text] [Related]

  • 7. Interaction between non-heme iron of lipoxygenases and cumene hydroperoxide: basis for enzyme activation, inactivation, and inhibition.
    Vahedi-Faridi A, Brault PA, Shah P, Kim YW, Dunham WR, Funk MO.
    J Am Chem Soc; 2004 Feb 25; 126(7):2006-15. PubMed ID: 14971933
    [Abstract] [Full Text] [Related]

  • 8. Functional assessment of specific amino acid residues of cytochrome P4501A1 using anti-peptide antibodies.
    Shen S, Strobel HW.
    Arch Biochem Biophys; 1995 Jun 20; 320(1):162-9. PubMed ID: 7793977
    [Abstract] [Full Text] [Related]

  • 9. Comparative homology modeling of human cytochrome P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin O-deethylation by site-directed mutagenesis and enzyme kinetic analysis.
    Lewis BC, Mackenzie PI, Miners JO.
    Arch Biochem Biophys; 2007 Dec 01; 468(1):58-69. PubMed ID: 17959138
    [Abstract] [Full Text] [Related]

  • 10. Alanine scanning mutagenesis of the testosterone binding site of rat 3 alpha-hydroxysteroid dehydrogenase demonstrates contact residues influence the rate-determining step.
    Heredia VV, Cooper WC, Kruger RG, Jin Y, Penning TM.
    Biochemistry; 2004 May 18; 43(19):5832-41. PubMed ID: 15134457
    [Abstract] [Full Text] [Related]

  • 11. The effect of reciprocal active site mutations in human cytochromes P450 1A1 and 1A2 on alkoxyresorufin metabolism.
    Liu J, Ericksen SS, Sivaneri M, Besspiata D, Fisher CW, Szklarz GD.
    Arch Biochem Biophys; 2004 Apr 01; 424(1):33-43. PubMed ID: 15019834
    [Abstract] [Full Text] [Related]

  • 12. Cytochrome b5 reductase: role of the si-face residues, proline 92 and tyrosine 93, in structure and catalysis.
    Marohnic CC, Crowley LJ, Davis CA, Smith ET, Barber MJ.
    Biochemistry; 2005 Feb 22; 44(7):2449-61. PubMed ID: 15709757
    [Abstract] [Full Text] [Related]

  • 13. Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1.
    Zheng YM, Fisher MB, Yokotani N, Fujii-Kuriyama Y, Rettie AE.
    Biochemistry; 1998 Sep 15; 37(37):12847-51. PubMed ID: 9737862
    [Abstract] [Full Text] [Related]

  • 14. Heterologous expression of an endogenous rat cytochrome b(5)/cytochrome b(5) reductase fusion protein: identification of histidines 62 and 85 as the heme axial ligands.
    Davis CA, Dhawan IK, Johnson MK, Barber MJ.
    Arch Biochem Biophys; 2002 Apr 01; 400(1):63-75. PubMed ID: 11913972
    [Abstract] [Full Text] [Related]

  • 15. Role of glutamic acid 216 in cytochrome P450 2D6 substrate binding and catalysis.
    Guengerich FP, Hanna IH, Martin MV, Gillam EM.
    Biochemistry; 2003 Feb 11; 42(5):1245-53. PubMed ID: 12564927
    [Abstract] [Full Text] [Related]

  • 16. Role of the conserved threonine 309 in mechanism of oxidation by cytochrome P450 2D6.
    Keizers PH, Schraven LH, de Graaf C, Hidestrand M, Ingelman-Sundberg M, van Dijk BR, Vermeulen NP, Commandeur JN.
    Biochem Biophys Res Commun; 2005 Dec 16; 338(2):1065-74. PubMed ID: 16269134
    [Abstract] [Full Text] [Related]

  • 17. Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency.
    Huang WC, Westlake AC, Maréchal JD, Joyce MG, Moody PC, Roberts GC.
    J Mol Biol; 2007 Oct 26; 373(3):633-51. PubMed ID: 17868686
    [Abstract] [Full Text] [Related]

  • 18. Formation of a novel reversible cytochrome P450 spectral intermediate: role of threonine 303 in P450 2E1 inactivation.
    Blobaum AL, Lu Y, Kent UM, Wang S, Hollenberg PF.
    Biochemistry; 2004 Sep 28; 43(38):11942-52. PubMed ID: 15379534
    [Abstract] [Full Text] [Related]

  • 19. Role of threonine 101 on the stability of the heme active site of cytochrome P450cam: multiwavelength circular dichroism studies.
    Manna SK, Mazumdar S.
    Biochemistry; 2006 Oct 24; 45(42):12715-22. PubMed ID: 17042489
    [Abstract] [Full Text] [Related]

  • 20. Threonine-205 in the F helix of p450 2B1 contributes to androgen 16 beta-hydroxylation activity and mechanism-based inactivation.
    Lin HL, Zhang H, Waskell L, Hollenberg PF.
    J Pharmacol Exp Ther; 2003 Aug 24; 306(2):744-51. PubMed ID: 12721329
    [Abstract] [Full Text] [Related]


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