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528 related items for PubMed ID: 11375493

  • 1. Metabolic regulation of brain Abeta by neprilysin.
    Iwata N, Tsubuki S, Takaki Y, Shirotani K, Lu B, Gerard NP, Gerard C, Hama E, Lee HJ, Saido TC.
    Science; 2001 May 25; 292(5521):1550-2. PubMed ID: 11375493
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of amyloid-beta peptide and Alzheimer's disease.
    Iwata N, Higuchi M, Saido TC.
    Pharmacol Ther; 2005 Nov 25; 108(2):129-48. PubMed ID: 16112736
    [Abstract] [Full Text] [Related]

  • 3. Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation.
    Saito T, Iwata N, Tsubuki S, Takaki Y, Takano J, Huang SM, Suemoto T, Higuchi M, Saido TC.
    Nat Med; 2005 Apr 25; 11(4):434-9. PubMed ID: 15778722
    [Abstract] [Full Text] [Related]

  • 4. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
    Li G, Percontino L, Sun Q, Qazi AS, Frederikse PH.
    Mol Vis; 2003 May 01; 9():179-83. PubMed ID: 12740567
    [Abstract] [Full Text] [Related]

  • 5. Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging.
    Iwata N, Takaki Y, Fukami S, Tsubuki S, Saido TC.
    J Neurosci Res; 2002 Nov 01; 70(3):493-500. PubMed ID: 12391610
    [Abstract] [Full Text] [Related]

  • 6. Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice.
    Lazarov O, Robinson J, Tang YP, Hairston IS, Korade-Mirnics Z, Lee VM, Hersh LB, Sapolsky RM, Mirnics K, Sisodia SS.
    Cell; 2005 Mar 11; 120(5):701-13. PubMed ID: 15766532
    [Abstract] [Full Text] [Related]

  • 7. Neprilysin activity and expression are controlled by nicastrin.
    Pardossi-Piquard R, Dunys J, Yu G, St George-Hyslop P, Alves da Costa C, Checler F.
    J Neurochem; 2006 May 11; 97(4):1052-6. PubMed ID: 16606360
    [Abstract] [Full Text] [Related]

  • 8. Neuronal neprilysin overexpression is associated with attenuation of Abeta-related spatial memory deficit.
    Poirier R, Wolfer DP, Welzl H, Tracy J, Galsworthy MJ, Nitsch RM, Mohajeri MH.
    Neurobiol Dis; 2006 Dec 11; 24(3):475-83. PubMed ID: 17008108
    [Abstract] [Full Text] [Related]

  • 9. Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits.
    Yao J, Petanceska SS, Montine TJ, Holtzman DM, Schmidt SD, Parker CA, Callahan MJ, Lipinski WJ, Bisgaier CL, Turner BA, Nixon RA, Martins RN, Ouimet C, Smith JD, Davies P, Laska E, Ehrlich ME, Walker LC, Mathews PM, Gandy S.
    J Neurochem; 2004 Aug 11; 90(4):1011-8. PubMed ID: 15287908
    [Abstract] [Full Text] [Related]

  • 10. Mice knock out for the histone acetyltransferase p300/CREB binding protein-associated factor develop a resistance to amyloid toxicity.
    Duclot F, Meffre J, Jacquet C, Gongora C, Maurice T.
    Neuroscience; 2010 May 19; 167(3):850-63. PubMed ID: 20219649
    [Abstract] [Full Text] [Related]

  • 11. Anti-amyloid activity of neprilysin in plaque-bearing mouse models of Alzheimer's disease.
    Mohajeri MH, Kuehnle K, Li H, Poirier R, Tracy J, Nitsch RM.
    FEBS Lett; 2004 Mar 26; 562(1-3):16-21. PubMed ID: 15043995
    [Abstract] [Full Text] [Related]

  • 12. Lack of neprilysin suffices to generate murine amyloid-like deposits in the brain and behavioral deficit in vivo.
    Madani R, Poirier R, Wolfer DP, Welzl H, Groscurth P, Lipp HP, Lu B, El Mouedden M, Mercken M, Nitsch RM, Mohajeri MH.
    J Neurosci Res; 2006 Dec 26; 84(8):1871-8. PubMed ID: 16998901
    [Abstract] [Full Text] [Related]

  • 13. Herpes simplex virus RNAi and neprilysin gene transfer vectors reduce accumulation of Alzheimer's disease-related amyloid-beta peptide in vivo.
    Hong CS, Goins WF, Goss JR, Burton EA, Glorioso JC.
    Gene Ther; 2006 Jul 26; 13(14):1068-79. PubMed ID: 16541122
    [Abstract] [Full Text] [Related]

  • 14. Etiology of sporadic Alzheimer's disease: somatostatin, neprilysin, and amyloid beta peptide.
    Hama E, Saido TC.
    Med Hypotheses; 2005 Jul 26; 65(3):498-500. PubMed ID: 15921860
    [Abstract] [Full Text] [Related]

  • 15. Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease.
    Wu ZL, Ciallella JR, Flood DG, O'Kane TM, Bozyczko-Coyne D, Savage MJ.
    Neurobiol Aging; 2006 Mar 26; 27(3):377-86. PubMed ID: 15927307
    [Abstract] [Full Text] [Related]

  • 16. Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders.
    Caccamo A, Oddo S, Sugarman MC, Akbari Y, LaFerla FM.
    Neurobiol Aging; 2005 May 26; 26(5):645-54. PubMed ID: 15708439
    [Abstract] [Full Text] [Related]

  • 17. Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology.
    Vepsäläinen S, Hiltunen M, Helisalmi S, Wang J, van Groen T, Tanila H, Soininen H.
    Neurosci Lett; 2008 Jun 20; 438(2):216-20. PubMed ID: 18455870
    [Abstract] [Full Text] [Related]

  • 18. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T, Kiliaan AJ, Kadish I.
    Neurobiol Dis; 2006 Sep 20; 23(3):653-62. PubMed ID: 16829076
    [Abstract] [Full Text] [Related]

  • 19. Altered expression of Abeta metabolism-associated molecules from D-galactose/AlCl(3) induced mouse brain.
    Luo Y, Niu F, Sun Z, Cao W, Zhang X, Guan D, Lv Z, Zhang B, Xu Y.
    Mech Ageing Dev; 2009 Apr 20; 130(4):248-52. PubMed ID: 19150622
    [Abstract] [Full Text] [Related]

  • 20. Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition.
    Iwata N, Tsubuki S, Takaki Y, Watanabe K, Sekiguchi M, Hosoki E, Kawashima-Morishima M, Lee HJ, Hama E, Sekine-Aizawa Y, Saido TC.
    Nat Med; 2000 Feb 20; 6(2):143-50. PubMed ID: 10655101
    [Abstract] [Full Text] [Related]

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