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183 related items for PubMed ID: 11375907

  • 1. Evidence that reduction of hepatocyte growth factor (HGF) is not required for peroxisome proliferator-induced hepatocyte proliferation.
    Kiss A, Ortiz-Aguayo R, Sharp R, Merlino G, Thorgeirsson SS, Gonzalez FJ, Peters JM.
    Carcinogenesis; 2001 Jun; 22(6):975-9. PubMed ID: 11375907
    [Abstract] [Full Text] [Related]

  • 2. Hepatocarcinogenesis by peroxisome proliferators.
    Suga T.
    J Toxicol Sci; 2004 Feb; 29(1):1-12. PubMed ID: 15018150
    [Abstract] [Full Text] [Related]

  • 3.
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  • 4. Involvement of hepatocyte growth factor on hepatocarcinogenesis induced by peroxisome proliferators.
    Suga T, Motoki Y, Tamura H, Watanabe T.
    Cell Biochem Biophys; 2000 Feb; 32 Spring():221-8. PubMed ID: 11330050
    [Abstract] [Full Text] [Related]

  • 5. Wy-14,643, a peroxisome proliferator, inhibits compensative cell proliferation and hepatocyte growth factor mRNA expression in the rat liver.
    Motoki Y, Tamura H, Watanabe T, Suga T.
    Cancer Lett; 1999 Jan 29; 135(2):145-50. PubMed ID: 10096422
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of hepatocarcinogenesis by the deletion of the p50 subunit of NF-kappaB in mice administered the peroxisome proliferator Wy-14,643.
    Glauert HP, Eyigor A, Tharappel JC, Cooper S, Lee EY, Spear BT.
    Toxicol Sci; 2006 Apr 29; 90(2):331-6. PubMed ID: 16434500
    [Abstract] [Full Text] [Related]

  • 7. Peroxisome proliferator-activated receptor alpha is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis.
    Peters JM, Rusyn I, Rose ML, Gonzalez FJ, Thurman RG.
    Carcinogenesis; 2000 Apr 29; 21(4):823-6. PubMed ID: 10753222
    [Abstract] [Full Text] [Related]

  • 8. Epigenetic effects of the continuous exposure to peroxisome proliferator WY-14,643 in mouse liver are dependent upon peroxisome proliferator activated receptor alpha.
    Pogribny IP, Tryndyak VP, Woods CG, Witt SE, Rusyn I.
    Mutat Res; 2007 Dec 01; 625(1-2):62-71. PubMed ID: 17586532
    [Abstract] [Full Text] [Related]

  • 9. Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.
    Rusyn I, Yamashina S, Segal BH, Schoonhoven R, Holland SM, Cattley RC, Swenberg JA, Thurman RG.
    Cancer Res; 2000 Sep 01; 60(17):4798-803. PubMed ID: 10987289
    [Abstract] [Full Text] [Related]

  • 10. Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643.
    Peters JM, Cattley RC, Gonzalez FJ.
    Carcinogenesis; 1997 Nov 01; 18(11):2029-33. PubMed ID: 9395198
    [Abstract] [Full Text] [Related]

  • 11. Mechanisms of extrahepatic tumor induction by peroxisome proliferators in male CD rats.
    Biegel LB, Hurtt ME, Frame SR, O'Connor JC, Cook JC.
    Toxicol Sci; 2001 Mar 01; 60(1):44-55. PubMed ID: 11222872
    [Abstract] [Full Text] [Related]

  • 12. Toxic effects of fumonisin in mouse liver are independent of the peroxisome proliferator-activated receptor alpha.
    Voss KA, Liu J, Anderson SP, Dunn C, Miller JD, Owen JR, Riley RT, Bacon CW, Corton JC.
    Toxicol Sci; 2006 Jan 01; 89(1):108-19. PubMed ID: 16221962
    [Abstract] [Full Text] [Related]

  • 13. WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase.
    Woods CG, Burns AM, Bradford BU, Ross PK, Kosyk O, Swenberg JA, Cunningham ML, Rusyn I.
    Toxicol Sci; 2007 Aug 01; 98(2):366-74. PubMed ID: 17483499
    [Abstract] [Full Text] [Related]

  • 14. Role of peroxisome proliferator-activated receptor alpha in altered cell cycle regulation in mouse liver.
    Peters JM, Aoyama T, Cattley RC, Nobumitsu U, Hashimoto T, Gonzalez FJ.
    Carcinogenesis; 1998 Nov 01; 19(11):1989-94. PubMed ID: 9855014
    [Abstract] [Full Text] [Related]

  • 15. Dietary glycine prevents the development of liver tumors caused by the peroxisome proliferator WY-14,643.
    Rose ML, Cattley RC, Dunn C, Wong V, Li X, Thurman RG.
    Carcinogenesis; 1999 Nov 01; 20(11):2075-81. PubMed ID: 10545408
    [Abstract] [Full Text] [Related]

  • 16. PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators.
    Gonzalez FJ, Shah YM.
    Toxicology; 2008 Apr 03; 246(1):2-8. PubMed ID: 18006136
    [Abstract] [Full Text] [Related]

  • 17. Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha.
    Cheung C, Akiyama TE, Ward JM, Nicol CJ, Feigenbaum L, Vinson C, Gonzalez FJ.
    Cancer Res; 2004 Jun 01; 64(11):3849-54. PubMed ID: 15172993
    [Abstract] [Full Text] [Related]

  • 18. Dietary glycine prevents increases in hepatocyte proliferation caused by the peroxisome proliferator WY-14,643.
    Rose ML, Germolec D, Arteel GE, Schoonhoven R, Thurman RG.
    Chem Res Toxicol; 1997 Oct 01; 10(10):1198-204. PubMed ID: 9348444
    [Abstract] [Full Text] [Related]

  • 19. Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats.
    Marsman DS, Cattley RC, Conway JG, Popp JA.
    Cancer Res; 1988 Dec 01; 48(23):6739-44. PubMed ID: 3180084
    [Abstract] [Full Text] [Related]

  • 20. Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis.
    Gyamfi MA, Wan YJ.
    J Biol Chem; 2009 Apr 03; 284(14):9321-30. PubMed ID: 19176532
    [Abstract] [Full Text] [Related]

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