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182 related items for PubMed ID: 11375961

  • 1. The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits Fas apoptosis upstream of bid in rodent hepatocytes.
    Takikawa Y, Miyoshi H, Rust C, Roberts P, Siegel R, Mandal PK, Millikan RE, Gores GJ.
    Gastroenterology; 2001 Jun; 120(7):1810-7. PubMed ID: 11375961
    [Abstract] [Full Text] [Related]

  • 2. Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
    Qiao L, Studer E, Leach K, McKinstry R, Gupta S, Decker R, Kukreja R, Valerie K, Nagarkatti P, El Deiry W, Molkentin J, Schmidt-Ullrich R, Fisher PB, Grant S, Hylemon PB, Dent P.
    Mol Biol Cell; 2001 Sep; 12(9):2629-45. PubMed ID: 11553704
    [Abstract] [Full Text] [Related]

  • 3. Bid antisense attenuates bile acid-induced apoptosis and cholestatic liver injury.
    Higuchi H, Miyoshi H, Bronk SF, Zhang H, Dean N, Gores GJ.
    J Pharmacol Exp Ther; 2001 Dec; 299(3):866-73. PubMed ID: 11714870
    [Abstract] [Full Text] [Related]

  • 4. Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.
    Faubion WA, Guicciardi ME, Miyoshi H, Bronk SF, Roberts PJ, Svingen PA, Kaufmann SH, Gores GJ.
    J Clin Invest; 1999 Jan; 103(1):137-45. PubMed ID: 9884343
    [Abstract] [Full Text] [Related]

  • 5. Relief of extrinsic pathway inhibition by the Bid-dependent mitochondrial release of Smac in Fas-mediated hepatocyte apoptosis.
    Li S, Zhao Y, He X, Kim TH, Kuharsky DK, Rabinowich H, Chen J, Du C, Yin XM.
    J Biol Chem; 2002 Jul 26; 277(30):26912-20. PubMed ID: 12011074
    [Abstract] [Full Text] [Related]

  • 6. TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid.
    Werner AB, de Vries E, Tait SW, Bontjer I, Borst J.
    J Biol Chem; 2002 Oct 25; 277(43):40760-7. PubMed ID: 12196516
    [Abstract] [Full Text] [Related]

  • 7. The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade.
    Rust C, Karnitz LM, Paya CV, Moscat J, Simari RD, Gores GJ.
    J Biol Chem; 2000 Jun 30; 275(26):20210-6. PubMed ID: 10770953
    [Abstract] [Full Text] [Related]

  • 8. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS, Poukkula M, Holmström TH, Heiskanen KM, Eriksson JE.
    J Immunol; 2002 Sep 15; 169(6):2851-60. PubMed ID: 12218097
    [Abstract] [Full Text] [Related]

  • 9. Execution of macrophage apoptosis by Mycobacterium avium through apoptosis signal-regulating kinase 1/p38 mitogen-activated protein kinase signaling and caspase 8 activation.
    Bhattacharyya A, Pathak S, Basak C, Law S, Kundu M, Basu J.
    J Biol Chem; 2003 Jul 18; 278(29):26517-25. PubMed ID: 12724324
    [Abstract] [Full Text] [Related]

  • 10. Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement.
    Zhao Y, Ding WX, Qian T, Watkins S, Lemasters JJ, Yin XM.
    Gastroenterology; 2003 Sep 18; 125(3):854-67. PubMed ID: 12949730
    [Abstract] [Full Text] [Related]

  • 11. Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis.
    Gómez-Angelats M, Cidlowski JA.
    J Biol Chem; 2001 Nov 30; 276(48):44944-52. PubMed ID: 11581255
    [Abstract] [Full Text] [Related]

  • 12. Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP).
    Suhara T, Mano T, Oliveira BE, Walsh K.
    Circ Res; 2001 Jul 06; 89(1):13-9. PubMed ID: 11440972
    [Abstract] [Full Text] [Related]

  • 13. The recruitment of Fas-associated death domain/caspase-8 in Ras-induced apoptosis.
    Chen CY, Juo P, Liou JS, Li CQ, Yu Q, Blenis J, Faller DV.
    Cell Growth Differ; 2001 Jun 06; 12(6):297-306. PubMed ID: 11432804
    [Abstract] [Full Text] [Related]

  • 14. B cell receptor cross-linking triggers a caspase-8-dependent apoptotic pathway that is independent of the death effector domain of Fas-associated death domain protein.
    Besnault L, Schrantz N, Auffredou MT, Leca G, Bourgeade MF, Vazquez A.
    J Immunol; 2001 Jul 15; 167(2):733-40. PubMed ID: 11441077
    [Abstract] [Full Text] [Related]

  • 15. Bile Acid Toxicity and Protein Kinases.
    Engin A.
    Adv Exp Med Biol; 2021 Jul 15; 1275():229-258. PubMed ID: 33539018
    [Abstract] [Full Text] [Related]

  • 16. NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis.
    Hatano E, Bennett BL, Manning AM, Qian T, Lemasters JJ, Brenner DA.
    Gastroenterology; 2001 Apr 15; 120(5):1251-62. PubMed ID: 11266388
    [Abstract] [Full Text] [Related]

  • 17. p38-mediated regulation of an Fas-associated death domain protein-independent pathway leading to caspase-8 activation during TGFbeta-induced apoptosis in human Burkitt lymphoma B cells BL41.
    Schrantz N, Bourgeade MF, Mouhamad S, Leca G, Sharma S, Vazquez A.
    Mol Biol Cell; 2001 Oct 15; 12(10):3139-51. PubMed ID: 11598198
    [Abstract] [Full Text] [Related]

  • 18. Activation of caspase-8 during N-(4-hydroxyphenyl)retinamide-induced apoptosis in Fas-defective hepatoma cells.
    You KR, Shin MN, Park RK, Lee SO, Kim DG.
    Hepatology; 2001 Dec 15; 34(6):1119-27. PubMed ID: 11732001
    [Abstract] [Full Text] [Related]

  • 19. TNF-alpha-mediated lysosomal permeabilization is FAN and caspase 8/Bid dependent.
    Werneburg N, Guicciardi ME, Yin XM, Gores GJ.
    Am J Physiol Gastrointest Liver Physiol; 2004 Aug 15; 287(2):G436-43. PubMed ID: 15075251
    [Abstract] [Full Text] [Related]

  • 20. HLA class II signals sensitize B lymphocytes to apoptosis via Fas/CD95 by increasing FADD recruitment to activated Fas and activation of caspases.
    Blancheteau V, Charron D, Mooney N.
    Hum Immunol; 2002 May 15; 63(5):375-83. PubMed ID: 11975981
    [Abstract] [Full Text] [Related]

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