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531 related items for PubMed ID: 11378681

  • 1. The suitability of hepatocyte culture models to study various aspects of drug metabolism.
    Nussler AK, Wang A, Neuhaus P, Fischer J, Yuan J, Liu L, Zeilinger K, Gerlach J, Arnold PJ, Albrecht W.
    ALTEX; 2001; 18(2):91-101. PubMed ID: 11378681
    [Abstract] [Full Text] [Related]

  • 2. [Effect evaluation of three cell culture models].
    Wang A, Xia T, Yuan J, Chen X.
    Wei Sheng Yan Jiu; 2003 Nov; 32(6):516-8. PubMed ID: 14963896
    [Abstract] [Full Text] [Related]

  • 3. Extending hepatocyte functionality for drug-testing applications using high-viscosity alginate-encapsulated three-dimensional cultures in bioreactors.
    Miranda JP, Rodrigues A, Tostões RM, Leite S, Zimmerman H, Carrondo MJ, Alves PM.
    Tissue Eng Part C Methods; 2010 Dec; 16(6):1223-32. PubMed ID: 20184401
    [Abstract] [Full Text] [Related]

  • 4. Interspecies difference in liver-specific functions and biotransformation of testosterone of primary rat, porcine and human hepatocyte in an organotypical sandwich culture.
    Langsch A, Giri S, Acikgöz A, Jasmund I, Frericks B, Bader A.
    Toxicol Lett; 2009 Aug 10; 188(3):173-9. PubMed ID: 19428196
    [Abstract] [Full Text] [Related]

  • 5. In-depth physiological characterization of primary human hepatocytes in a 3D hollow-fiber bioreactor.
    Mueller D, Tascher G, Müller-Vieira U, Knobeloch D, Nuessler AK, Zeilinger K, Heinzle E, Noor F.
    J Tissue Eng Regen Med; 2011 Aug 10; 5(8):e207-18. PubMed ID: 21442764
    [Abstract] [Full Text] [Related]

  • 6. Analysis of drug metabolism activities in a miniaturized liver cell bioreactor for use in pharmacological studies.
    Hoffmann SA, Müller-Vieira U, Biemel K, Knobeloch D, Heydel S, Lübberstedt M, Nüssler AK, Andersson TB, Gerlach JC, Zeilinger K.
    Biotechnol Bioeng; 2012 Dec 10; 109(12):3172-81. PubMed ID: 22688505
    [Abstract] [Full Text] [Related]

  • 7. [Liver cell culture in bioreactors for in vitro drug studies as an alternative to animal testing].
    Zeilinger K, Auth S, Unger J, Grebe A, Mao L, Petrik M, Holland G, Appel K, Nüssler A, Neuhaus P, Gerlach J.
    ALTEX; 2000 Dec 10; 17(1):3-10. PubMed ID: 11103107
    [Abstract] [Full Text] [Related]

  • 8. Hepatocytes cultured in alginate microspheres: an optimized technique to study enzyme induction.
    Ringel M, von Mach MA, Santos R, Feilen PJ, Brulport M, Hermes M, Bauer AW, Schormann W, Tanner B, Schön MR, Oesch F, Hengstler JG.
    Toxicology; 2005 Jan 05; 206(1):153-67. PubMed ID: 15590115
    [Abstract] [Full Text] [Related]

  • 9. Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes.
    Mathijs K, Kienhuis AS, Brauers KJ, Jennen DG, Lahoz A, Kleinjans JC, van Delft JH.
    Drug Metab Dispos; 2009 Jun 05; 37(6):1305-11. PubMed ID: 19251822
    [Abstract] [Full Text] [Related]

  • 10. Comparison of coumarin-induced toxicity between sandwich-cultured primary rat hepatocytes and rats in vivo: a toxicogenomics approach.
    Kienhuis AS, Wortelboer HM, Hoflack JC, Moonen EJ, Kleinjans JC, van Ommen B, van Delft JH, Stierum RH.
    Drug Metab Dispos; 2006 Dec 05; 34(12):2083-90. PubMed ID: 16963487
    [Abstract] [Full Text] [Related]

  • 11. Human hepatocyte functions in a crossed hollow fiber membrane bioreactor.
    De Bartolo L, Salerno S, Curcio E, Piscioneri A, Rende M, Morelli S, Tasselli F, Bader A, Drioli E.
    Biomaterials; 2009 May 05; 30(13):2531-43. PubMed ID: 19185912
    [Abstract] [Full Text] [Related]

  • 12. Merging bioreactor technology with 3D hepatocyte-fibroblast culturing approaches: Improved in vitro models for toxicological applications.
    Leite SB, Teixeira AP, Miranda JP, Tostões RM, Clemente JJ, Sousa MF, Carrondo MJ, Alves PM.
    Toxicol In Vitro; 2011 Jun 05; 25(4):825-32. PubMed ID: 21315144
    [Abstract] [Full Text] [Related]

  • 13. Serum-free collagen sandwich cultures of adult rat hepatocytes maintain liver-like properties long term: a valuable model for in vitro toxicity and drug-drug interaction studies.
    Tuschl G, Hrach J, Walter Y, Hewitt PG, Mueller SO.
    Chem Biol Interact; 2009 Sep 14; 181(1):124-37. PubMed ID: 19482013
    [Abstract] [Full Text] [Related]

  • 14. Cultivation of primary porcine hepatocytes in an OXY-HFB for use as a bioartificial liver device.
    Jasmund I, Langsch A, Simmoteit R, Bader A.
    Biotechnol Prog; 2002 Sep 14; 18(4):839-46. PubMed ID: 12153319
    [Abstract] [Full Text] [Related]

  • 15. In vitro evaluation of major in vivo drug metabolic pathways using primary human hepatocytes and HepaRG cells in suspension and a dynamic three-dimensional bioreactor system.
    Darnell M, Ulvestad M, Ellis E, Weidolf L, Andersson TB.
    J Pharmacol Exp Ther; 2012 Oct 14; 343(1):134-44. PubMed ID: 22776955
    [Abstract] [Full Text] [Related]

  • 16. Induction, expression and maintenance of cytochrome P450 isoforms in long-term cultures of primary human hepatocytes.
    Yuan J, Liu L, Shimada M, Wang A, Ruhnke M, Heeckt P, Muller AR, Nussler NC, Neuhaus P, Nussler A.
    ALTEX; 2004 Oct 14; 21 Suppl 3():3-11. PubMed ID: 15057403
    [Abstract] [Full Text] [Related]

  • 17. A dual-functional fibrous scaffold enhances P450 activity of cultured primary rat hepatocytes.
    Chua KN, Tang YN, Quek CH, Ramakrishna S, Leong KW, Mao HQ.
    Acta Biomater; 2007 Sep 14; 3(5):643-50. PubMed ID: 17532276
    [Abstract] [Full Text] [Related]

  • 18. Effects of phenobarbital on metabolism and toxicity of diclofenac sodium in rat hepatocytes in vitro.
    Wang AG, Xia T, Yuan J, Yu RA, Yang KD, Chen XM, Qu W, Waalkes MP.
    Food Chem Toxicol; 2004 Oct 14; 42(10):1647-53. PubMed ID: 15304311
    [Abstract] [Full Text] [Related]

  • 19. Rat primary hepatocytes show enhanced performance and sensitivity to acetaminophen during three-dimensional culture on a polystyrene scaffold designed for routine use.
    Schutte M, Fox B, Baradez MO, Devonshire A, Minguez J, Bokhari M, Przyborski S, Marshall D.
    Assay Drug Dev Technol; 2011 Oct 14; 9(5):475-86. PubMed ID: 21675871
    [Abstract] [Full Text] [Related]

  • 20. Prediction of in vitro intrinsic clearance from hepatocytes: comparison of suspensions and monolayer cultures.
    Griffin SJ, Houston JB.
    Drug Metab Dispos; 2005 Jan 14; 33(1):115-20. PubMed ID: 15608354
    [Abstract] [Full Text] [Related]

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