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331 related items for PubMed ID: 11402328

  • 1. The SV40 small t-antigen prevents mammary gland differentiation and induces breast cancer formation in transgenic mice; truncated large T-antigen molecules harboring the intact p53 and pRb binding region do not have this effect.
    Goetz F, Tzeng YJ, Guhl E, Merker J, Graessmann M, Graessmann A.
    Oncogene; 2001 Apr 26; 20(18):2325-32. PubMed ID: 11402328
    [Abstract] [Full Text] [Related]

  • 2. SV40 T/t-antigen induces premature mammary gland involution by apoptosis and selects for p53 missense mutation in mammary tumors.
    Tzeng YJ, Zimmermann C, Guhl E, Berg B, Avantaggiati ML, Graessmann A.
    Oncogene; 1998 Apr 23; 16(16):2103-14. PubMed ID: 9572491
    [Abstract] [Full Text] [Related]

  • 3. HBX causes cyclin D1 overexpression and development of breast cancer in transgenic animals that are heterozygous for p53.
    Klein A, Guhl E, Tzeng YJ, Fuhrhop J, Levrero M, Graessmann M, Graessmann A.
    Oncogene; 2003 May 15; 22(19):2910-9. PubMed ID: 12771941
    [Abstract] [Full Text] [Related]

  • 4. SV40 T-antigen induces breast cancer formation with a high efficiency in lactating and virgin WAP-SV-T transgenic animals but with a low efficiency in ovariectomized animals.
    Santarelli R, Tzeng YJ, Zimmermann C, Guhl E, Graessmann A.
    Oncogene; 1996 Feb 01; 12(3):495-505. PubMed ID: 8637705
    [Abstract] [Full Text] [Related]

  • 5. Expression of a viral oncoprotein during mammary gland development alters cell fate and function: induction of p53-independent apoptosis is followed by impaired milk protein production in surviving cells.
    Li M, Hu J, Heermeier K, Hennighausen L, Furth PA.
    Cell Growth Differ; 1996 Jan 01; 7(1):3-11. PubMed ID: 8788028
    [Abstract] [Full Text] [Related]

  • 6. Understanding mammary gland development through the imbalanced expression of growth regulators.
    Robinson GW, Smith GH, Gallahan D, Zimmer A, Furth PA, Hennighausen L.
    Dev Dyn; 1996 Jun 01; 206(2):159-68. PubMed ID: 8725283
    [Abstract] [Full Text] [Related]

  • 7. WAP-TAg transgenic mice and the study of dysregulated cell survival, proliferation, and mutation during breast carcinogenesis.
    Li M, Lewis B, Capuco AV, Laucirica R, Furth PA.
    Oncogene; 2000 Feb 21; 19(8):1010-9. PubMed ID: 10713684
    [Abstract] [Full Text] [Related]

  • 8. Apoptosis and remodeling of mammary gland tissue during involution proceeds through p53-independent pathways.
    Li M, Hu J, Heermeier K, Hennighausen L, Furth PA.
    Cell Growth Differ; 1996 Jan 21; 7(1):13-20. PubMed ID: 8788029
    [Abstract] [Full Text] [Related]

  • 9. Functional mammary gland development and oncogene-induced tumor formation are not affected by the absence of the retinoblastoma gene.
    Robinson GW, Wagner KU, Hennighausen L.
    Oncogene; 2001 Oct 25; 20(48):7115-9. PubMed ID: 11704837
    [Abstract] [Full Text] [Related]

  • 10. Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis.
    Gallahan D, Jhappan C, Robinson G, Hennighausen L, Sharp R, Kordon E, Callahan R, Merlino G, Smith GH.
    Cancer Res; 1996 Apr 15; 56(8):1775-85. PubMed ID: 8620493
    [Abstract] [Full Text] [Related]

  • 11. Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway.
    Akli S, Van Pelt CS, Bui T, Multani AS, Chang S, Johnson D, Tucker S, Keyomarsi K.
    Cancer Res; 2007 Aug 01; 67(15):7212-22. PubMed ID: 17671189
    [Abstract] [Full Text] [Related]

  • 12. Transgenic mice with mammary gland targeted expression of human cortactin do not develop (pre-malignant) breast tumors: studies in MMTV-cortactin and MMTV-cortactin/-cyclin D1 bitransgenic mice.
    van Rossum AG, van Bragt MP, Schuuring-Scholtes E, van der Ploeg JC, van Krieken JH, Kluin PM, Schuuring E.
    BMC Cancer; 2006 Mar 14; 6():58. PubMed ID: 16536875
    [Abstract] [Full Text] [Related]

  • 13. Tumors initiated by constitutive Cdk2 activation exhibit transforming growth factor beta resistance and acquire paracrine mitogenic stimulation during progression.
    Corsino P, Davis B, Law M, Chytil A, Forrester E, Nørgaard P, Teoh N, Law B.
    Cancer Res; 2007 Apr 01; 67(7):3135-44. PubMed ID: 17409420
    [Abstract] [Full Text] [Related]

  • 14. Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis.
    Forrester E, Chytil A, Bierie B, Aakre M, Gorska AE, Sharif-Afshar AR, Muller WJ, Moses HL.
    Cancer Res; 2005 Mar 15; 65(6):2296-302. PubMed ID: 15781643
    [Abstract] [Full Text] [Related]

  • 15. Pituitary neoplasia induced by expression of human neurotropic polyomavirus, JCV, early genome in transgenic mice.
    Gordon J, Del Valle L, Otte J, Khalili K.
    Oncogene; 2000 Oct 05; 19(42):4840-6. PubMed ID: 11039901
    [Abstract] [Full Text] [Related]

  • 16. Differential expression of cell cycle regulators in phenotypic variants of transgenically induced bladder tumors: implications for tumor behavior.
    Garcia-España A, Salazar E, Sun TT, Wu XR, Pellicer A.
    Cancer Res; 2005 Feb 15; 65(4):1150-7. PubMed ID: 15734997
    [Abstract] [Full Text] [Related]

  • 17. Role of T antigen interactions with p53 in tumorigenesis.
    Pipas JM, Levine AJ.
    Semin Cancer Biol; 2001 Feb 15; 11(1):23-30. PubMed ID: 11243896
    [Abstract] [Full Text] [Related]

  • 18. Haploid inactivation of the amplified-in-breast cancer 3 coactivator reduces the inhibitory effect of peroxisome proliferator-activated receptor gamma and retinoid X receptor on cell proliferation and accelerates polyoma middle-T antigen-induced mammary tumorigenesis in mice.
    Zhang H, Kuang SQ, Liao L, Zhou S, Xu J.
    Cancer Res; 2004 Oct 01; 64(19):7169-77. PubMed ID: 15466215
    [Abstract] [Full Text] [Related]

  • 19. Notch1-induced mammary tumor development is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors.
    Ling H, Sylvestre JR, Jolicoeur P.
    Oncogene; 2010 Aug 12; 29(32):4543-54. PubMed ID: 20562911
    [Abstract] [Full Text] [Related]

  • 20. Overexpression and forced activation of stat5 in mammary gland of transgenic mice promotes cellular proliferation, enhances differentiation, and delays postlactational apoptosis.
    Iavnilovitch E, Groner B, Barash I.
    Mol Cancer Res; 2002 Nov 12; 1(1):32-47. PubMed ID: 12496367
    [Abstract] [Full Text] [Related]

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