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Journal Abstract Search

178 related items for PubMed ID: 11408372

  • 1. Studies comparing in vivo:in vitro metabolism of three pharmaceutical compounds in rat, dog, monkey, and human using cryopreserved hepatocytes, microsomes, and collagen gel immobilized hepatocyte cultures.
    Hewitt NJ, Bühring KU, Dasenbrock J, Haunschild J, Ladstetter B, Utesch D.
    Drug Metab Dispos; 2001 Jul; 29(7):1042-50. PubMed ID: 11408372
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  • 2. Metabolism of prazosin in rat, dog, and human liver microsomes and cryopreserved rat and human hepatocytes and characterization of metabolites by liquid chromatography/tandem mass spectrometry.
    Erve JC, Vashishtha SC, DeMaio W, Talaat RE.
    Drug Metab Dispos; 2007 Jun; 35(6):908-16. PubMed ID: 17353349
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  • 3. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA.
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
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  • 4. Metabolism of MK-0524, a prostaglandin D2 receptor 1 antagonist, in microsomes and hepatocytes from preclinical species and humans.
    Dean BJ, Chang S, Silva Elipe MV, Xia YQ, Braun M, Soli E, Zhao Y, Franklin RB, Karanam B.
    Drug Metab Dispos; 2007 Feb; 35(2):283-92. PubMed ID: 17132765
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  • 6. Identification of BVT.2938 metabolites by LC/MS and LC/MS/MS after in vitro incubations with liver microsomes and hepatocytes.
    Edlund PO, Baranczewski P.
    J Pharm Biomed Anal; 2004 Mar 10; 34(5):1079-90. PubMed ID: 15019042
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  • 8. Evaluation of the metabolism of propranolol by linear ion trap technology in mouse, rat, dog, monkey, and human cryopreserved hepatocytes.
    Baughman TM, Talarico CL, Soglia JR.
    Rapid Commun Mass Spectrom; 2009 Jul 10; 23(14):2146-50. PubMed ID: 19517456
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  • 12. Comparative metabolism of flunarizine in rats, dogs and man: an in vitro study with subcellular liver fractions and isolated hepatocytes.
    Lavrijsen K, van Houdt J, van Dyck D, Hendrickx J, Bockx M, Hurkmans R, Meuldermans W, Le Jeune L, Lauwers W, Heykants J.
    Xenobiotica; 1992 Jul 10; 22(7):815-36. PubMed ID: 1455902
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  • 14. Comparison of amphetamine metabolism using isolated hepatocytes from five species including human.
    Green CE, LeValley SE, Tyson CA.
    J Pharmacol Exp Ther; 1986 Jun 10; 237(3):931-6. PubMed ID: 3712286
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  • 15. Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance.
    Brown HS, Griffin M, Houston JB.
    Drug Metab Dispos; 2007 Feb 10; 35(2):293-301. PubMed ID: 17132764
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  • 18. Species differences in the elimination of a peroxisome proliferator-activated receptor agonist highlighted by oxidative metabolism of its acyl glucuronide.
    Kochansky CJ, Xia YQ, Wang S, Cato B, Creighton M, Vincent SH, Franklin RB, Reed JR.
    Drug Metab Dispos; 2005 Dec 10; 33(12):1894-904. PubMed ID: 16183782
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  • 19. Biotransformation of the anti-angiogenic compound SU5416.
    Antonian L, Zhang H, Yang C, Wagner G, Shawver LK, Shet M, Ogilvie B, Madan A, Parkinson A.
    Drug Metab Dispos; 2000 Dec 10; 28(12):1505-12. PubMed ID: 11095590
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  • 20. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
    Yao HT, Wu YS, Chang YW, Hsieh HP, Chen WC, Lan SJ, Chen CT, Chao YS, Chang L, Sun HY, Yeh TK.
    Drug Metab Dispos; 2007 Jul 10; 35(7):1042-9. PubMed ID: 17403915
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