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Journal Abstract Search

178 related items for PubMed ID: 11408372

  • 21. Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolites.
    Wang WW, Khetani SR, Krzyzewski S, Duignan DB, Obach RS.
    Drug Metab Dispos; 2010 Oct; 38(10):1900-5. PubMed ID: 20595376
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  • 22. Cryopreservation of rat and mouse hepatocytes. II. Assessment of metabolic capacity using testosterone metabolism.
    Swales NJ, Johnson T, Caldwell J.
    Drug Metab Dispos; 1996 Nov; 24(11):1224-30. PubMed ID: 8937857
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  • 23. Comparison of fresh and cryopreserved rat hepatocyte suspensions for the prediction of in vitro intrinsic clearance.
    Griffin SJ, Houston JB.
    Drug Metab Dispos; 2004 May; 32(5):552-8. PubMed ID: 15100178
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  • 24. Altered AZT (3'-azido-3'-deoxythymidine) glucuronidation kinetics in liver microsomes as an explanation for underprediction of in vivo clearance: comparison to hepatocytes and effect of incubation environment.
    Engtrakul JJ, Foti RS, Strelevitz TJ, Fisher MB.
    Drug Metab Dispos; 2005 Nov; 33(11):1621-7. PubMed ID: 16049128
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  • 25. Prediction of human pharmacokinetics from preclinical information: comparative accuracy of quantitative prediction approaches.
    Hosea NA, Collard WT, Cole S, Maurer TS, Fang RX, Jones H, Kakar SM, Nakai Y, Smith BJ, Webster R, Beaumont K.
    J Clin Pharmacol; 2009 May; 49(5):513-33. PubMed ID: 19299532
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  • 27. Evaluation of fresh and cryopreserved hepatocytes as in vitro drug metabolism tools for the prediction of metabolic clearance.
    McGinnity DF, Soars MG, Urbanowicz RA, Riley RJ.
    Drug Metab Dispos; 2004 Nov; 32(11):1247-53. PubMed ID: 15286053
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  • 31. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
    Kalgutkar AS, Hatch HL, Kosea F, Nguyen HT, Choo EF, McClure KF, Taylor TJ, Henne KR, Kuperman AV, Dombroski MA, Letavic MA.
    Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
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  • 33. Cryopreservation of rat and dog hepatocytes for studies of xenobiotic metabolism and activation.
    Powis G, Santone KS, Melder DC, Thomas L, Moore DJ, Wilke TJ.
    Drug Metab Dispos; 1987 Nov; 15(6):826-32. PubMed ID: 2893709
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  • 34. Cryopreserved rat, dog and monkey hepatocytes: measurement of drug metabolizing enzymes in suspensions and cultures.
    Hewitt NJ, Utesch D.
    Hum Exp Toxicol; 2004 Jun; 23(6):307-16. PubMed ID: 15301157
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  • 35. Characterization of two phase I metabolites of bendamustine in human liver microsomes and in cancer patients treated with bendamustine hydrochloride.
    Teichert J, Baumann F, Chao Q, Franklin C, Bailey B, Hennig L, Caca K, Schoppmeyer K, Patzak U, Preiss R.
    Cancer Chemother Pharmacol; 2007 May; 59(6):759-70. PubMed ID: 16957931
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  • 37. Metabolism of capsaicin by cytochrome P450 produces novel dehydrogenated metabolites and decreases cytotoxicity to lung and liver cells.
    Reilly CA, Ehlhardt WJ, Jackson DA, Kulanthaivel P, Mutlib AE, Espina RJ, Moody DE, Crouch DJ, Yost GS.
    Chem Res Toxicol; 2003 Mar; 16(3):336-49. PubMed ID: 12641434
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  • 38. Prediction of in vitro intrinsic clearance from hepatocytes: comparison of suspensions and monolayer cultures.
    Griffin SJ, Houston JB.
    Drug Metab Dispos; 2005 Jan; 33(1):115-20. PubMed ID: 15608354
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  • 39. Metabolism of temelastine (SK&F 93944) in hepatocytes from rat, dog, cynomolgus monkey and man.
    Oldham HG, Standring P, Norman SJ, Blake TJ, Beattie I, Cox PJ, Chenery RJ.
    Drug Metab Dispos; 1990 Jan; 18(2):146-52. PubMed ID: 1971564
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  • 40. Comparative metabolism of SC-42867 and SC-51089, two PGE2 antagonists, in rat and human hepatocyte cultures.
    Lee K, Vandenberghe Y, Herin M, Cavalier R, Beck D, Li A, Verbeke N, Lesne M, Roba J.
    Xenobiotica; 1994 Jan; 24(1):25-36. PubMed ID: 8165819
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