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558 related items for PubMed ID: 11408609

  • 1. Sequence-dependent potentiation of paclitaxel-mediated apoptosis in human leukemia cells by inhibitors of the mitogen-activated protein kinase kinase/mitogen-activated protein kinase pathway.
    Yu C, Wang S, Dent P, Grant S.
    Mol Pharmacol; 2001 Jul; 60(1):143-54. PubMed ID: 11408609
    [Abstract] [Full Text] [Related]

  • 2. Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells.
    Dai Y, Yu C, Singh V, Tang L, Wang Z, McInistry R, Dent P, Grant S.
    Cancer Res; 2001 Jul 01; 61(13):5106-15. PubMed ID: 11431348
    [Abstract] [Full Text] [Related]

  • 3. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
    Yu C, Krystal G, Varticovksi L, McKinstry R, Rahmani M, Dent P, Grant S.
    Cancer Res; 2002 Jan 01; 62(1):188-99. PubMed ID: 11782377
    [Abstract] [Full Text] [Related]

  • 4. Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
    Vrana JA, Grant S.
    Blood; 2001 Apr 01; 97(7):2105-14. PubMed ID: 11264178
    [Abstract] [Full Text] [Related]

  • 5. [The role of mitogen-activated protein kinase cascades in inhibition of proliferation in human prostate carcinoma cells by raloxifene: an in vitro experiment].
    Zhang YX, Kong CZ.
    Zhonghua Yi Xue Za Zhi; 2008 Jan 22; 88(4):271-5. PubMed ID: 18361842
    [Abstract] [Full Text] [Related]

  • 6. The cyclin-dependent kinase inhibitor (CDKI) flavopiridol disrupts phorbol 12-myristate 13-acetate-induced differentiation and CDKI expression while enhancing apoptosis in human myeloid leukemia cells.
    Cartee L, Wang Z, Decker RH, Chellappan SP, Fusaro G, Hirsch KG, Sankala HM, Dent P, Grant S.
    Cancer Res; 2001 Mar 15; 61(6):2583-91. PubMed ID: 11289135
    [Abstract] [Full Text] [Related]

  • 7. Selective potentiation of paclitaxel (taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines.
    McDaid HM, Horwitz SB.
    Mol Pharmacol; 2001 Aug 15; 60(2):290-301. PubMed ID: 11455016
    [Abstract] [Full Text] [Related]

  • 8. Paclitaxel induces prolonged activation of the Ras/MEK/ERK pathway independently of activating the programmed cell death machinery.
    Okano J, Rustgi AK.
    J Biol Chem; 2001 Jun 01; 276(22):19555-64. PubMed ID: 11278851
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells.
    Stadheim TA, Xiao H, Eastman A.
    Cancer Res; 2001 Feb 15; 61(4):1533-40. PubMed ID: 11245462
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase enhances chemotherapeutic effects on H460 human non-small cell lung cancer cells through activation of apoptosis.
    Hu Y, Bally M, Dragowska WH, Mayer L.
    Mol Cancer Ther; 2003 Jul 15; 2(7):641-9. PubMed ID: 12883037
    [Abstract] [Full Text] [Related]

  • 11. Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.
    Park MT, Choi JA, Kim MJ, Um HD, Bae S, Kang CM, Cho CK, Kang S, Chung HY, Lee YS, Lee SJ.
    J Biol Chem; 2003 Dec 12; 278(50):50624-34. PubMed ID: 14522966
    [Abstract] [Full Text] [Related]

  • 12. Coadministration of UCN-01 with MEK1/2 inhibitors potently induces apoptosis in BCR/ABL+ leukemia cells sensitive and resistant to ST1571.
    Yu C, Dai Y, Dent P, Grant S.
    Cancer Biol Ther; 2002 Dec 12; 1(6):674-82. PubMed ID: 12642693
    [Abstract] [Full Text] [Related]

  • 13. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
    Yu C, Rahmani M, Dai Y, Conrad D, Krystal G, Dent P, Grant S.
    Cancer Res; 2003 Apr 15; 63(8):1822-33. PubMed ID: 12702569
    [Abstract] [Full Text] [Related]

  • 14. Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 Cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells.
    Shiah SG, Chuang SE, Kuo ML.
    Mol Pharmacol; 2001 Feb 15; 59(2):254-62. PubMed ID: 11160861
    [Abstract] [Full Text] [Related]

  • 15. The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells.
    Maggio SC, Rosato RR, Kramer LB, Dai Y, Rahmani M, Paik DS, Czarnik AC, Payne SG, Spiegel S, Grant S.
    Cancer Res; 2004 Apr 01; 64(7):2590-600. PubMed ID: 15059916
    [Abstract] [Full Text] [Related]

  • 16. The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.
    Yu C, Rahmani M, Dent P, Grant S.
    Exp Cell Res; 2004 May 01; 295(2):555-66. PubMed ID: 15093752
    [Abstract] [Full Text] [Related]

  • 17. Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways.
    Hahn M, Li W, Yu C, Rahmani M, Dent P, Grant S.
    Mol Cancer Ther; 2005 Mar 01; 4(3):457-70. PubMed ID: 15767555
    [Abstract] [Full Text] [Related]

  • 18. MEK and p38MAPK inhibitors potentiate TNF-alpha induced apoptosis in U937 cells.
    Nakada S, Kawano T, Saito-akita S, Iwase S, Horiguchi-Yamada J, Ohno T, Yamada H.
    Anticancer Res; 2001 Mar 01; 21(1A):167-71. PubMed ID: 11299730
    [Abstract] [Full Text] [Related]

  • 19. A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation.
    Miyoshi N, Uchida K, Osawa T, Nakamura Y.
    Cancer Res; 2004 Mar 15; 64(6):2134-42. PubMed ID: 15026354
    [Abstract] [Full Text] [Related]

  • 20. Induction of tumor necrosis factor by bryostatin 1 is involved in synergistic interactions with paclitaxel in human myeloid leukemia cells.
    Wang S, Wang Z, Dent P, Grant S.
    Blood; 2003 May 01; 101(9):3648-57. PubMed ID: 12522001
    [Abstract] [Full Text] [Related]

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