These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

155 related items for PubMed ID: 11415994

  • 1. Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity.
    Ho SC, Van Sande J, Lefort A, Vassart G, Costagliola S.
    Endocrinology; 2001 Jul; 142(7):2760-7. PubMed ID: 11415994
    [Abstract] [Full Text] [Related]

  • 2. Effects of mutations involving cysteine residues distal to the S281HCC motif at the C-terminus on the functional characteristics of a truncated ectodomain-only thyrotropin receptor anchored on glycosylphosphatidyl-inositol.
    Ho SC, Goh SS, Li S, Khoo DH, Paterson M.
    Thyroid; 2008 Dec; 18(12):1313-9. PubMed ID: 18976165
    [Abstract] [Full Text] [Related]

  • 3. The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding.
    Gu WX, Du GG, Kopp P, Rentoumis A, Albanese C, Kohn LD, Madison LD, Jameson JL.
    Endocrinology; 1995 Jul; 136(7):3146-53. PubMed ID: 7789342
    [Abstract] [Full Text] [Related]

  • 4. Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
    Kosugi S, Okajima F, Ban T, Hidaka A, Shenker A, Kohn LD.
    Mol Endocrinol; 1993 Aug; 7(8):1009-20. PubMed ID: 7901757
    [Abstract] [Full Text] [Related]

  • 5. Identification and functional characterization of two novel activating thyrotropin receptor mutants in toxic thyroid follicular adenomas.
    Castro I, Lima L, Seoane R, Lado-Abeal J.
    Thyroid; 2009 Jun; 19(6):645-9. PubMed ID: 19499991
    [Abstract] [Full Text] [Related]

  • 6. Cysteine 390 mutation of the TSH receptor modulates its ectodomain as an inverse agonist on the serpentine domain with decrease in basal constitutive activity.
    Ho SC, Goh SS, Su Q, Khoo DH.
    Mol Cell Endocrinol; 2005 Dec 21; 245(1-2):158-68. PubMed ID: 16364538
    [Abstract] [Full Text] [Related]

  • 7. Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist.
    Vlaeminck-Guillem V, Ho SC, Rodien P, Vassart G, Costagliola S.
    Mol Endocrinol; 2002 Apr 21; 16(4):736-46. PubMed ID: 11923470
    [Abstract] [Full Text] [Related]

  • 8. Further studies of amino acids (268-304) in thyrotropin (TSH)--lutropin/chorionic gonadotropin (LH/CG) receptor chimeras: cysteine-301 is important in TSH binding and receptor tertiary structure.
    Akamizu T, Inoue D, Kosugi S, Kohn LD, Mori T.
    Thyroid; 1994 Apr 21; 4(1):43-8. PubMed ID: 8054860
    [Abstract] [Full Text] [Related]

  • 9. Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropin receptors.
    Kosugi S, Ban T, Akamizu T, Kohn LD.
    Mol Endocrinol; 1992 Feb 21; 6(2):168-80. PubMed ID: 1349156
    [Abstract] [Full Text] [Related]

  • 10. Interactions between the extracellular domain and the extracellular loops as well as the 6th transmembrane domain are necessary for TSH receptor activation.
    Neumann S, Claus M, Paschke R.
    Eur J Endocrinol; 2005 Apr 21; 152(4):625-34. PubMed ID: 15817920
    [Abstract] [Full Text] [Related]

  • 11. Evidence that the thyroid-stimulating hormone (TSH) receptor transmembrane domain influences kinetics of TSH binding to the receptor ectodomain.
    Chen CR, McLachlan SM, Rapoport B.
    J Biol Chem; 2011 Feb 25; 286(8):6219-24. PubMed ID: 21190937
    [Abstract] [Full Text] [Related]

  • 12. The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone-receptor interaction and antagonist design.
    Zhang M, Tong KP, Fremont V, Chen J, Narayan P, Puett D, Weintraub BD, Szkudlinski MW.
    Endocrinology; 2000 Sep 25; 141(9):3514-7. PubMed ID: 10965926
    [Abstract] [Full Text] [Related]

  • 13. On the functional importance of thyrotropin receptor intramolecular cleavage.
    Chazenbalk GD, Tanaka K, McLachlan SM, Rapoport B.
    Endocrinology; 1999 Oct 25; 140(10):4516-20. PubMed ID: 10499506
    [Abstract] [Full Text] [Related]

  • 14. Evidence that the C terminus of the A subunit suppresses thyrotropin receptor constitutive activity.
    Chen CR, Chazenbalk GD, McLachlan SM, Rapoport B.
    Endocrinology; 2003 Sep 25; 144(9):3821-7. PubMed ID: 12933653
    [Abstract] [Full Text] [Related]

  • 15. Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain.
    Duprez L, Parma J, Costagliola S, Hermans J, Van Sande J, Dumont JE, Vassart G.
    FEBS Lett; 1997 Jun 16; 409(3):469-74. PubMed ID: 9224711
    [Abstract] [Full Text] [Related]

  • 16. Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia.
    Tonacchera M, Van Sande J, Cetani F, Swillens S, Schvartz C, Winiszewski P, Portmann L, Dumont JE, Vassart G, Parma J.
    J Clin Endocrinol Metab; 1996 Feb 16; 81(2):547-54. PubMed ID: 8636266
    [Abstract] [Full Text] [Related]

  • 17. The hinge region of the TSH receptor stabilizes ligand binding and determines different signaling profiles of human and bovine TSH.
    Jaeschke H, Schaarschmidt J, Günther R, Mueller S.
    Endocrinology; 2011 Oct 16; 152(10):3986-96. PubMed ID: 21846801
    [Abstract] [Full Text] [Related]

  • 18. Constitutive activation of the thyrotropin receptor by deletion of a portion of the extracellular domain.
    Zhang ML, Sugawa H, Kosugi S, Mori T.
    Biochem Biophys Res Commun; 1995 Jun 06; 211(1):205-10. PubMed ID: 7779086
    [Abstract] [Full Text] [Related]

  • 19. Point mutations of the thyrotropin receptor determining structural requirements for its ability to bind thyrotropin and to stimulate adenylate cyclase activity.
    Gustavsson B, Westermark B, Heldin NE.
    Biochem Biophys Res Commun; 1994 Mar 15; 199(2):612-8. PubMed ID: 8135801
    [Abstract] [Full Text] [Related]

  • 20. Role of the carboxyl-terminal half of the extracellular domain of the human thyrotropin receptor in signal transduction.
    Nagayama Y, Rapoport B.
    Endocrinology; 1992 Aug 15; 131(2):548-52. PubMed ID: 1322272
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 8.