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650 related items for PubMed ID: 11423913

  • 1. Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity.
    Zhang L, Himi T, Morita I, Murota S.
    Cell Death Differ; 2001 May; 8(5):528-36. PubMed ID: 11423913
    [Abstract] [Full Text] [Related]

  • 2. Role of NF-kappaB and PI 3-kinase/Akt in TNF-alpha-induced cytotoxicity in microvascular endothelial cells.
    Zhou Z, Gengaro P, Wang W, Wang XQ, Li C, Faubel S, Rivard C, Schrier RW.
    Am J Physiol Renal Physiol; 2008 Oct; 295(4):F932-41. PubMed ID: 18632801
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of TNF-alpha-induced neutrophil apoptosis by crystals of calcium pyrophosphate dihydrate is mediated by the extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways up-stream of caspase 3.
    Tudan C, Jackson JK, Blanis L, Pelech SL, Burt HM.
    J Immunol; 2000 Nov 15; 165(10):5798-806. PubMed ID: 11067939
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.
    Uddin S, Hussain AR, Al-Hussein KA, Manogaran PS, Wickrema A, Gutierrez MI, Bhatia KG.
    Clin Cancer Res; 2005 Apr 15; 11(8):3102-8. PubMed ID: 15837766
    [Abstract] [Full Text] [Related]

  • 5. TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways.
    Secchiero P, Gonelli A, Carnevale E, Milani D, Pandolfi A, Zella D, Zauli G.
    Circulation; 2003 May 06; 107(17):2250-6. PubMed ID: 12668516
    [Abstract] [Full Text] [Related]

  • 6. Neuroprotection by transforming growth factor-beta1 involves activation of nuclear factor-kappaB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1,2 signaling pathways.
    Zhu Y, Culmsee C, Klumpp S, Krieglstein J.
    Neuroscience; 2004 May 06; 123(4):897-906. PubMed ID: 14751283
    [Abstract] [Full Text] [Related]

  • 7. A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells.
    Madge LA, Pober JS.
    J Biol Chem; 2000 May 19; 275(20):15458-65. PubMed ID: 10748004
    [Abstract] [Full Text] [Related]

  • 8. Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
    MacKeigan JP, Taxman DJ, Hunter D, Earp HS, Graves LM, Ting JP.
    Clin Cancer Res; 2002 Jul 19; 8(7):2091-9. PubMed ID: 12114408
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of nuclear factor kappaB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor alpha in mice.
    Imose M, Nagaki M, Naiki T, Osawa Y, Brenner DA, Asano T, Hayashi H, Kato T, Moriwaki H.
    Liver Int; 2003 Oct 19; 23(5):386-96. PubMed ID: 14708901
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis.
    Madge LA, Li JH, Choi J, Pober JS.
    J Biol Chem; 2003 Jun 06; 278(23):21295-306. PubMed ID: 12663669
    [Abstract] [Full Text] [Related]

  • 11. Insulin regulates cleavage of procaspase-9 via binding of X chromosome-linked inhibitor of apoptosis protein in HT-29 cells.
    Kim JE, Tannenbaum SR.
    Cancer Res; 2004 Dec 15; 64(24):9070-5. PubMed ID: 15604274
    [Abstract] [Full Text] [Related]

  • 12. Decreased apoptosis in polyamine depleted IEC-6 cells depends on Akt-mediated NF-kappaB activation but not GSK3beta activity.
    Bhattacharya S, Ray RM, Johnson LR.
    Apoptosis; 2005 Aug 15; 10(4):759-76. PubMed ID: 16133867
    [Abstract] [Full Text] [Related]

  • 13. Constitutive NF-kappaB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway.
    Birkenkamp KU, Geugien M, Schepers H, Westra J, Lemmink HH, Vellenga E.
    Leukemia; 2004 Jan 15; 18(1):103-12. PubMed ID: 14574326
    [Abstract] [Full Text] [Related]

  • 14. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
    Yu C, Rahmani M, Dai Y, Conrad D, Krystal G, Dent P, Grant S.
    Cancer Res; 2003 Apr 15; 63(8):1822-33. PubMed ID: 12702569
    [Abstract] [Full Text] [Related]

  • 15. Negative regulatory role of PI3-kinase in TNF-induced tumor necrosis.
    Matschurat S, Blum S, Mitnacht-Kraus R, Dijkman HB, Kanal L, De Waal RM, Clauss M.
    Int J Cancer; 2003 Oct 20; 107(1):30-7. PubMed ID: 12925953
    [Abstract] [Full Text] [Related]

  • 16. Divergence in the anti-apoptotic signalling pathways used by nerve growth factor and basic fibroblast growth factor (bFGF) in PC12 cells: rescue by bFGF involves protein kinase C delta.
    Wert MM, Palfrey HC.
    Biochem J; 2000 Nov 15; 352 Pt 1(Pt 1):175-82. PubMed ID: 11062070
    [Abstract] [Full Text] [Related]

  • 17. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells.
    Panka DJ, Mano T, Suhara T, Walsh K, Mier JW.
    J Biol Chem; 2001 Mar 09; 276(10):6893-6. PubMed ID: 11145953
    [Abstract] [Full Text] [Related]

  • 18. Andrographolide suppresses endothelial cell apoptosis via activation of phosphatidyl inositol-3-kinase/Akt pathway.
    Chen JH, Hsiao G, Lee AR, Wu CC, Yen MH.
    Biochem Pharmacol; 2004 Apr 01; 67(7):1337-45. PubMed ID: 15013849
    [Abstract] [Full Text] [Related]

  • 19. TNF-alpha signal transduction in rat neonatal cardiac myocytes: definition of pathways generating from the TNF-alpha receptor.
    Condorelli G, Morisco C, Latronico MV, Claudio PP, Dent P, Tsichlis P, Condorelli G, Frati G, Drusco A, Croce CM, Napoli C.
    FASEB J; 2002 Nov 01; 16(13):1732-7. PubMed ID: 12409315
    [Abstract] [Full Text] [Related]

  • 20. Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient mice.
    Bedogni B, O'Neill MS, Welford SM, Bouley DM, Giaccia AJ, Denko NC, Powell MB.
    Cancer Res; 2004 Apr 01; 64(7):2552-60. PubMed ID: 15059911
    [Abstract] [Full Text] [Related]

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