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Journal Abstract Search

99 related items for PubMed ID: 11425524

  • 1. Dibasic inhibitors of human mast cell tryptase. Part 3: identification of a series of potent and selective inhibitors containing the benzamidine functionality.
    Dener JM, Rice KD, Newcomb WS, Wang VR, Young WB, Gangloff AR, Kuo EY, Cregar L, Putnam D, Wong M.
    Bioorg Med Chem Lett; 2001 Jul 09; 11(13):1629-33. PubMed ID: 11425524
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  • 2. Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptase.
    Hopkins CR, Czekaj M, Kaye SS, Gao Z, Pribish J, Pauls H, Liang G, Sides K, Cramer D, Cairns J, Luo Y, Lim HK, Vaz R, Rebello S, Maignan S, Dupuy A, Mathieu M, Levell J.
    Bioorg Med Chem Lett; 2005 Jun 02; 15(11):2734-7. PubMed ID: 15911249
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  • 4. Inhibition of human mast cell tryptase by benzamidine derivatives.
    Stürzebecher J, Prasa D, Sommerhoff CP.
    Biol Chem Hoppe Seyler; 1992 Oct 02; 373(10):1025-30. PubMed ID: 1418674
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  • 5. Potent selective nonpeptidic inhibitors of human lung tryptase.
    Burgess LE, Newhouse BJ, Ibrahim P, Rizzi J, Kashem MA, Hartman A, Brandhuber BJ, Wright CD, Thomson DS, Vigers GP, Koch K.
    Proc Natl Acad Sci U S A; 1999 Jul 20; 96(15):8348-52. PubMed ID: 10411878
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  • 13. Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of betaII tryptase.
    Levell J, Astles P, Eastwood P, Cairns J, Houille O, Aldous S, Merriman G, Whiteley B, Pribish J, Czekaj M, Liang G, Maignan S, Guilloteau JP, Dupuy A, Davidson J, Harrison T, Morley A, Watson S, Fenton G, McCarthy C, Romano J, Mathew R, Engers D, Gardyan M, Sides K, Kwong J, Tsay J, Rebello S, Shen L, Wang J, Luo Y, Giardino O, Lim HK, Smith K, Pauls H.
    Bioorg Med Chem; 2005 Apr 15; 13(8):2859-72. PubMed ID: 15781396
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  • 16. Dibasic inhibitors of human mast cell tryptase. Part 2: structure-activity relationships and requirements for potent activity.
    Rice KD, Wang VR, Gangloff AR, Kuo EY, Dener JM, Newcomb WS, Young WB, Putnam D, Cregar L, Wong M, Simpson PJ.
    Bioorg Med Chem Lett; 2000 Oct 16; 10(20):2361-6. PubMed ID: 11055356
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  • 18. Inhibitors of mast cell tryptase beta as therapeutics for the treatment of asthma and inflammatory disorders.
    Cairns JA.
    Pulm Pharmacol Ther; 2005 Oct 16; 18(1):55-66. PubMed ID: 15607128
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