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196 related items for PubMed ID: 11429058

  • 1. Coordinate involvement of cell cycle arrest and apoptosis strengthen the effect of FTY720.
    Nagahara Y, Matsuoka Y, Saito K, Ikekita M, Higuchi S, Shinomiya T.
    Jpn J Cancer Res; 2001 Jun; 92(6):680-7. PubMed ID: 11429058
    [Abstract] [Full Text] [Related]

  • 2. Distinct pathways of apoptosis triggered by FTY720, etoposide, and anti-Fas antibody in human T-lymphoma cell line (Jurkat cells).
    Fujino M, Li XK, Kitazawa Y, Guo L, Kawasaki M, Funeshima N, Amano T, Suzuki S.
    J Pharmacol Exp Ther; 2002 Mar; 300(3):939-45. PubMed ID: 11861801
    [Abstract] [Full Text] [Related]

  • 3. Immunosuppressant FTY720 induces apoptosis by direct induction of permeability transition and release of cytochrome c from mitochondria.
    Nagahara Y, Ikekita M, Shinomiya T.
    J Immunol; 2000 Sep 15; 165(6):3250-9. PubMed ID: 10975841
    [Abstract] [Full Text] [Related]

  • 4. A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells.
    Matsuoka Y, Nagahara Y, Ikekita M, Shinomiya T.
    Br J Pharmacol; 2003 Apr 15; 138(7):1303-12. PubMed ID: 12711631
    [Abstract] [Full Text] [Related]

  • 5. FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation.
    Lee TK, Man K, Ho JW, Sun CK, Ng KT, Wang XH, Wong YC, Ng IO, Xu R, Fan ST.
    Carcinogenesis; 2004 Dec 15; 25(12):2397-405. PubMed ID: 15297371
    [Abstract] [Full Text] [Related]

  • 6. T cell selective apoptosis by a novel immunosuppressant, FTY720, is closely regulated with Bcl-2.
    Nagahara Y, Ikekita M, Shinomiya T.
    Br J Pharmacol; 2002 Dec 15; 137(7):953-62. PubMed ID: 12429567
    [Abstract] [Full Text] [Related]

  • 7. FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma.
    Liu Q, Zhao X, Frissora F, Ma Y, Santhanam R, Jarjoura D, Lehman A, Perrotti D, Chen CS, Dalton JT, Muthusamy N, Byrd JC.
    Blood; 2008 Jan 01; 111(1):275-84. PubMed ID: 17761520
    [Abstract] [Full Text] [Related]

  • 8. PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice.
    Zheng T, Meng X, Wang J, Chen X, Yin D, Liang Y, Song X, Pan S, Jiang H, Liu L.
    J Cell Biochem; 2010 Sep 01; 111(1):218-28. PubMed ID: 20506484
    [Abstract] [Full Text] [Related]

  • 9. FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling.
    Lu Z, Wang J, Zheng T, Liang Y, Yin D, Song R, Pei T, Pan S, Jiang H, Liu L.
    BMC Cancer; 2014 Oct 25; 14():783. PubMed ID: 25344679
    [Abstract] [Full Text] [Related]

  • 10. Altered expression of signaling genes in Jurkat cells upon FTY720 induced apoptosis.
    Wang F, Tan W, Guo D, Zhu X, Qian K, He S.
    Int J Mol Sci; 2010 Sep 02; 11(9):3087-105. PubMed ID: 20957081
    [Abstract] [Full Text] [Related]

  • 11. Induction of apoptosis in human bladder cancer cells in vitro and in vivo caused by FTY720 treatment.
    Azuma H, Takahara S, Horie S, Muto S, Otsuki Y, Katsuoka Y.
    J Urol; 2003 Jun 02; 169(6):2372-7. PubMed ID: 12771800
    [Abstract] [Full Text] [Related]

  • 12. Activation of caspases and mitochondria in FTY720-mediated apoptosis in human T cell line Jurkat.
    Fujino M, Li XK, Guo L, Amano T, Suzuki S.
    Int Immunopharmacol; 2001 Oct 02; 1(11):2011-21. PubMed ID: 11606032
    [Abstract] [Full Text] [Related]

  • 13. Anticarcinogenic effect of FTY720 in human prostate carcinoma DU145 cells: modulation of mitogenic signaling, FAK, cell-cycle entry and apoptosis.
    Permpongkosol S, Wang JD, Takahara S, Matsumiya K, Nonomura N, Nishimura K, Tsujimura A, Kongkanand A, Okuyama A.
    Int J Cancer; 2002 Mar 10; 98(2):167-72. PubMed ID: 11857403
    [Abstract] [Full Text] [Related]

  • 14. Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway.
    Matsuda S, Minowa A, Suzuki S, Koyasu S.
    J Immunol; 1999 Mar 15; 162(6):3321-6. PubMed ID: 10092785
    [Abstract] [Full Text] [Related]

  • 15. FTY720, a novel immunosuppressive agent, induces apoptosis in human glioma cells.
    Sonoda Y, Yamamoto D, Sakurai S, Hasegawa M, Aizu-Yokota E, Momoi T, Kasahara T.
    Biochem Biophys Res Commun; 2001 Feb 23; 281(2):282-8. PubMed ID: 11181042
    [Abstract] [Full Text] [Related]

  • 16. Effects of phosphorylation of immunomodulatory agent FTY720 (fingolimod) on antiproliferative activity against breast and colon cancer cells.
    Nagaoka Y, Otsuki K, Fujita T, Uesato S.
    Biol Pharm Bull; 2008 Jun 23; 31(6):1177-81. PubMed ID: 18520051
    [Abstract] [Full Text] [Related]

  • 17. Elimination of cell-cycle regulators during caspase-3-dependent apoptosis caused by an immunosuppressant, FTY720.
    Lee YS, Nakajima H, Tsuruga M, Magae J.
    Biosci Biotechnol Biochem; 2003 Mar 23; 67(3):467-74. PubMed ID: 12723592
    [Abstract] [Full Text] [Related]

  • 18. Role of extracelluar regulated protein kinases in FTY720-induced apoptosis of leukemia cell lines HL-60 and U937.
    Li D, Zhang Y, Hu X, Cao W, Huang W.
    J Huazhong Univ Sci Technolog Med Sci; 2004 Mar 23; 24(1):45-7. PubMed ID: 15165113
    [Abstract] [Full Text] [Related]

  • 19. A novel immunosuppressant, FTY720, increases the efficiency of a superantigen-induced peripheral T-cell deletion whilst inhibiting negative selection in the thymus.
    Shimizu C, Li X, Kimura M, Hashimoto K, Sugaya K, Kubo M, Suzuki S, Nakayama T.
    Immunology; 1998 Aug 23; 94(4):503-12. PubMed ID: 9767438
    [Abstract] [Full Text] [Related]

  • 20. Selective cancer cell apoptosis induced by FTY720; evidence for a Bcl-dependent pathway and impairment in ERK activity.
    Azuma H, Horie S, Muto S, Otsuki Y, Matsumoto K, Morimoto J, Gotoh R, Okuyama A, Suzuki S, Katsuoka Y, Takahara S.
    Anticancer Res; 2003 Aug 23; 23(4):3183-93. PubMed ID: 12926052
    [Abstract] [Full Text] [Related]

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