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543 related items for PubMed ID: 11439090

  • 1. Temporal relationships between ceramide production, caspase activation and mitochondrial dysfunction in cell lines with varying sensitivity to anti-Fas-induced apoptosis.
    Rodriguez-Lafrasse C, Alphonse G, Broquet P, Aloy MT, Louisot P, Rousson R.
    Biochem J; 2001 Jul 15; 357(Pt 2):407-16. PubMed ID: 11439090
    [Abstract] [Full Text] [Related]

  • 2. Ceramide induces activation of the mitochondrial/caspases pathway in Jurkat and SCC61 cells sensitive to gamma-radiation but activation of this sequence is defective in radioresistant SQ20B cells.
    Alphonse G, Aloy MT, Broquet P, Gerard JP, Louisot P, Rousson R, Rodriguez-Lafrasse C.
    Int J Radiat Biol; 2002 Sep 15; 78(9):821-35. PubMed ID: 12428923
    [Abstract] [Full Text] [Related]

  • 3. Ceramide-induced apoptosis in fas-resistant Hodgkin's disease cell lines is caspase independent.
    Metkar SS, Anand M, Manna PP, Naresh KN, Nadkarni JJ.
    Exp Cell Res; 2000 Feb 25; 255(1):18-29. PubMed ID: 10666330
    [Abstract] [Full Text] [Related]

  • 4. Caspase independent/dependent regulation of K(+), cell shrinkage, and mitochondrial membrane potential during lymphocyte apoptosis.
    Bortner CD, Cidlowski JA.
    J Biol Chem; 1999 Jul 30; 274(31):21953-62. PubMed ID: 10419518
    [Abstract] [Full Text] [Related]

  • 5. Increase of nuclear ceramide through caspase-3-dependent regulation of the "sphingomyelin cycle" in Fas-induced apoptosis.
    Watanabe M, Kitano T, Kondo T, Yabu T, Taguchi Y, Tashima M, Umehara H, Domae N, Uchiyama T, Okazaki T.
    Cancer Res; 2004 Feb 01; 64(3):1000-7. PubMed ID: 14871831
    [Abstract] [Full Text] [Related]

  • 6. Synthetic 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3, and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in HL-60 cells by a mechanism which involves caspase-2 activation but not Fas signaling.
    Perchellet EM, Wang Y, Weber RL, Sperfslage BJ, Lou K, Crossland J, Hua DH, Perchellet JP.
    Biochem Pharmacol; 2004 Feb 01; 67(3):523-37. PubMed ID: 15037204
    [Abstract] [Full Text] [Related]

  • 7. Redox-sensitive events in Fas-induced apoptosis in human NK cells include ceramide generation and protein tyrosine dephosphorylation.
    Furuke K, Bloom ET.
    Int Immunol; 1998 Sep 01; 10(9):1261-72. PubMed ID: 9786425
    [Abstract] [Full Text] [Related]

  • 8. B cell receptor cross-linking triggers a caspase-8-dependent apoptotic pathway that is independent of the death effector domain of Fas-associated death domain protein.
    Besnault L, Schrantz N, Auffredou MT, Leca G, Bourgeade MF, Vazquez A.
    J Immunol; 2001 Jul 15; 167(2):733-40. PubMed ID: 11441077
    [Abstract] [Full Text] [Related]

  • 9. Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death.
    Miguet C, Monier S, Bettaieb A, Athias A, Besséde G, Laubriet A, Lemaire S, Néel D, Gambert P, Lizard G.
    Cell Death Differ; 2001 Jan 15; 8(1):83-99. PubMed ID: 11313706
    [Abstract] [Full Text] [Related]

  • 10. Partial ATP depletion induces Fas- and caspase-mediated apoptosis in MDCK cells.
    Feldenberg LR, Thevananther S, del Rio M, de Leon M, Devarajan P.
    Am J Physiol; 1999 Jun 15; 276(6):F837-46. PubMed ID: 10362772
    [Abstract] [Full Text] [Related]

  • 11. Elevated extracellular [K+] inhibits death-receptor- and chemical-mediated apoptosis prior to caspase activation and cytochrome c release.
    Thompson GJ, Langlais C, Cain K, Conley EC, Cohen GM.
    Biochem J; 2001 Jul 01; 357(Pt 1):137-45. PubMed ID: 11415444
    [Abstract] [Full Text] [Related]

  • 12. Antitumor triptycene bisquinones induce a caspase-independent release of mitochondrial cytochrome c and a caspase-2-mediated activation of initiator caspase-8 and -9 in HL-60 cells by a mechanism which does not involve Fas signaling.
    Perchellet EM, Wang Y, Weber RL, Lou K, Hua DH, Perchellet JP.
    Anticancer Drugs; 2004 Nov 01; 15(10):929-46. PubMed ID: 15514562
    [Abstract] [Full Text] [Related]

  • 13. Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells.
    Cuvillier O, Edsall L, Spiegel S.
    J Biol Chem; 2000 May 26; 275(21):15691-700. PubMed ID: 10747891
    [Abstract] [Full Text] [Related]

  • 14. Overcoming resistance to gamma-rays in squamous carcinoma cells by poly-drug elevation of ceramide levels.
    Alphonse G, Bionda C, Aloy MT, Ardail D, Rousson R, Rodriguez-Lafrasse C.
    Oncogene; 2004 Apr 08; 23(15):2703-15. PubMed ID: 15048093
    [Abstract] [Full Text] [Related]

  • 15. Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells.
    Gamen S, Anel A, Pérez-Galán P, Lasierra P, Johnson D, Piñeiro A, Naval J.
    Exp Cell Res; 2000 Jul 10; 258(1):223-35. PubMed ID: 10912804
    [Abstract] [Full Text] [Related]

  • 16. B cell receptor-stimulated mitochondrial phospholipase A2 activation and resultant disruption of mitochondrial membrane potential correlate with the induction of apoptosis in WEHI-231 B cells.
    Katz E, Deehan MR, Seatter S, Lord C, Sturrock RD, Harnett MM.
    J Immunol; 2001 Jan 01; 166(1):137-47. PubMed ID: 11123286
    [Abstract] [Full Text] [Related]

  • 17. Resistance to CD95/Fas-induced and ceramide-mediated apoptosis of human melanoma cells is caused by a defective mitochondrial cytochrome c release.
    Raisova M, Bektas M, Wieder T, Daniel P, Eberle J, Orfanos CE, Geilen CC.
    FEBS Lett; 2000 May 04; 473(1):27-32. PubMed ID: 10802053
    [Abstract] [Full Text] [Related]

  • 18. Caspases are the main executioners of Fas-mediated apoptosis, irrespective of the ceramide signalling pathway.
    Gamen S, Anel A, Piñeiro A, Naval J.
    Cell Death Differ; 1998 Mar 04; 5(3):241-9. PubMed ID: 10200470
    [Abstract] [Full Text] [Related]

  • 19. A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.
    Pardo J, Pérez-Galán P, Gamen S, Marzo I, Monleón I, Kaspar AA, Susín SA, Kroemer G, Krensky AM, Naval J, Anel A.
    J Immunol; 2001 Aug 01; 167(3):1222-9. PubMed ID: 11466337
    [Abstract] [Full Text] [Related]

  • 20. CPP32 inhibition prevents Fas-induced ceramide generation and apoptosis in human cells.
    Gamen S, Marzo I, Anel A, Piñeiro A, Naval J.
    FEBS Lett; 1996 Jul 22; 390(2):232-7. PubMed ID: 8706867
    [Abstract] [Full Text] [Related]

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