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432 related items for PubMed ID: 11439092

  • 1. Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions.
    Leslie NR, Bennett D, Gray A, Pass I, Hoang-Xuan K, Downes CP.
    Biochem J; 2001 Jul 15; 357(Pt 2):427-35. PubMed ID: 11439092
    [Abstract] [Full Text] [Related]

  • 2. Analysis of the cellular functions of PTEN using catalytic domain and C-terminal mutations: differential effects of C-terminal deletion on signalling pathways downstream of phosphoinositide 3-kinase.
    Leslie NR, Gray A, Pass I, Orchiston EA, Downes CP.
    Biochem J; 2000 Mar 15; 346 Pt 3(Pt 3):827-33. PubMed ID: 10698713
    [Abstract] [Full Text] [Related]

  • 3. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
    Ramaswamy S, Nakamura N, Vazquez F, Batt DB, Perera S, Roberts TM, Sellers WR.
    Proc Natl Acad Sci U S A; 1999 Mar 02; 96(5):2110-5. PubMed ID: 10051603
    [Abstract] [Full Text] [Related]

  • 4. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.
    Haas-Kogan D, Shalev N, Wong M, Mills G, Yount G, Stokoe D.
    Curr Biol; 1998 Oct 22; 8(21):1195-8. PubMed ID: 9799739
    [Abstract] [Full Text] [Related]

  • 5. Antagonism of PI 3-kinase-dependent signalling pathways by the tumour suppressor protein, PTEN.
    Downes CP, Bennett D, McConnachie G, Leslie NR, Pass I, MacPhee C, Patel L, Gray A.
    Biochem Soc Trans; 2001 Nov 22; 29(Pt 6):846-51. PubMed ID: 11709086
    [Abstract] [Full Text] [Related]

  • 6. Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors.
    Freeburn RW, Wright KL, Burgess SJ, Astoul E, Cantrell DA, Ward SG.
    J Immunol; 2002 Nov 15; 169(10):5441-50. PubMed ID: 12421919
    [Abstract] [Full Text] [Related]

  • 7. 5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells.
    Taylor V, Wong M, Brandts C, Reilly L, Dean NM, Cowsert LM, Moodie S, Stokoe D.
    Mol Cell Biol; 2000 Sep 15; 20(18):6860-71. PubMed ID: 10958682
    [Abstract] [Full Text] [Related]

  • 8. PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells.
    Li DM, Sun H.
    Proc Natl Acad Sci U S A; 1998 Dec 22; 95(26):15406-11. PubMed ID: 9860981
    [Abstract] [Full Text] [Related]

  • 9. The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway.
    Arico S, Petiot A, Bauvy C, Dubbelhuis PF, Meijer AJ, Codogno P, Ogier-Denis E.
    J Biol Chem; 2001 Sep 21; 276(38):35243-6. PubMed ID: 11477064
    [Abstract] [Full Text] [Related]

  • 10. The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.
    Walker SM, Leslie NR, Perera NM, Batty IH, Downes CP.
    Biochem J; 2004 Apr 15; 379(Pt 2):301-7. PubMed ID: 14711368
    [Abstract] [Full Text] [Related]

  • 11. The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway.
    Wu X, Senechal K, Neshat MS, Whang YE, Sawyers CL.
    Proc Natl Acad Sci U S A; 1998 Dec 22; 95(26):15587-91. PubMed ID: 9861013
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.
    Edwards LA, Thiessen B, Dragowska WH, Daynard T, Bally MB, Dedhar S.
    Oncogene; 2005 May 19; 24(22):3596-605. PubMed ID: 15782140
    [Abstract] [Full Text] [Related]

  • 13. PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.
    Paramio JM, Navarro M, Segrelles C, Gómez-Casero E, Jorcano JL.
    Oncogene; 1999 Dec 09; 18(52):7462-8. PubMed ID: 10602505
    [Abstract] [Full Text] [Related]

  • 14. PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies.
    Dahia PL, Aguiar RC, Alberta J, Kum JB, Caron S, Sill H, Marsh DJ, Ritz J, Freedman A, Stiles C, Eng C.
    Hum Mol Genet; 1999 Feb 09; 8(2):185-93. PubMed ID: 9931326
    [Abstract] [Full Text] [Related]

  • 15. The INPP4B paradox: Like PTEN, but different.
    Hamila SA, Ooms LM, Rodgers SJ, Mitchell CA.
    Adv Biol Regul; 2021 Dec 09; 82():100817. PubMed ID: 34216856
    [Abstract] [Full Text] [Related]

  • 16. PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.
    Weng LP, Smith WM, Dahia PL, Ziebold U, Gil E, Lees JA, Eng C.
    Cancer Res; 1999 Nov 15; 59(22):5808-14. PubMed ID: 10582703
    [Abstract] [Full Text] [Related]

  • 17. The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.
    Vazquez F, Sellers WR.
    Biochim Biophys Acta; 2000 Feb 14; 1470(1):M21-35. PubMed ID: 10656987
    [No Abstract] [Full Text] [Related]

  • 18. Pten signaling in gliomas.
    Knobbe CB, Merlo A, Reifenberger G.
    Neuro Oncol; 2002 Jul 14; 4(3):196-211. PubMed ID: 12084351
    [Abstract] [Full Text] [Related]

  • 19. Enhanced protein kinase B/Akt signalling in pituitary tumours.
    Musat M, Korbonits M, Kola B, Borboli N, Hanson MR, Nanzer AM, Grigson J, Jordan S, Morris DG, Gueorguiev M, Coculescu M, Basu S, Grossman AB.
    Endocr Relat Cancer; 2005 Jun 14; 12(2):423-33. PubMed ID: 15947113
    [Abstract] [Full Text] [Related]

  • 20. Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes.
    Ono H, Katagiri H, Funaki M, Anai M, Inukai K, Fukushima Y, Sakoda H, Ogihara T, Onishi Y, Fujishiro M, Kikuchi M, Oka Y, Asano T.
    Mol Endocrinol; 2001 Aug 14; 15(8):1411-22. PubMed ID: 11463863
    [Abstract] [Full Text] [Related]

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